Search Results - "NOOTHALAPATI, Hemanth"
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Non-invasive diagnosis of colorectal cancer by Raman spectroscopy: Recent developments in liquid biopsy and endoscopy approaches
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-09-2021)“…[Display omitted] •CRC is one of the leading causes of cancer deaths around the globe.•Screening people >45 leads to early diagnosis and can save lives…”
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Microfluidics and surface-enhanced Raman spectroscopy, a win-win combination?
Published in Lab on a chip (15-02-2022)“…With the continuous development in nanoscience and nanotechnology, analytical techniques like surface-enhanced Raman spectroscopy (SERS) render structural and…”
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Exploring Metabolic Pathways in Vivo by a Combined Approach of Mixed Stable Isotope-Labeled Raman Microspectroscopy and Multivariate Curve Resolution Analysis
Published in Analytical chemistry (Washington) (05-08-2014)“…Understanding cellular metabolism is a major challenge in current systems biology and has triggered extensive metabolomics research, which in most cases…”
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Biological and Medical Applications of Multivariate Curve Resolution Assisted Raman Spectroscopy
Published in Analytical Sciences (01-01-2017)“…Biological specimens such as cells, tissues and biofluids (urine, blood) contain mixtures of many different biomolecules, all of which contribute to a Raman…”
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Label-free Chemical Imaging of Fungal Spore Walls by Raman Microscopy and Multivariate Curve Resolution Analysis
Published in Scientific reports (09-06-2016)“…Fungal cell walls are medically important since they represent a drug target site for antifungal medication. So far there is no method to directly visualize…”
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Fibril formation and therapeutic targeting of amyloid-like structures in a yeast model of adenine accumulation
Published in Nature communications (08-01-2019)“…The extension of the amyloid hypothesis to include non-protein metabolite assemblies invokes a paradigm for the pathology of inborn error of metabolism…”
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Identification of Molecular Basis for Objective Discrimination of Breast Cancer Cells (MCF-7) from Normal Human Mammary Epithelial Cells by Raman Microspectroscopy and Multivariate Curve Resolution Analysis
Published in International journal of molecular sciences (14-01-2021)“…Raman spectroscopy (RS), a non-invasive and label-free method, has been suggested to improve accuracy of cytological and even histopathological diagnosis. To…”
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Salivary Raman spectroscopy: Understanding alterations in saliva of tobacco habitués and oral cancer subjects
Published in Vibrational spectroscopy (01-09-2022)“…Saliva a non-invasive biofluid, offers diagnostic potential due to its vicinity with tumour along with systemic pooling of biomarkers. The present study…”
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Curcumin Targeted Drug Delivery Using Iron Oxide Nanoparticle Incorporated Magnetic Responsive Carboxymethyl Cellulose Hydrogel
Published in Polymer science. Series B (01-04-2024)“…In recent years, magnetic-responsive hydrogels, alongside other smart hydrogel materials, have emerged as a focal point of research owing to their exceptional…”
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Imaging phospholipid conformational disorder and packing in giant multilamellar liposome by confocal Raman microspectroscopy
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-12-2017)“…Liposomes are closed phospholipid bilayer systems that have profound applications in fundamental cell biology, pharmaceutics and medicine. Depending on the…”
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Importance of weak interactions and conformational equilibrium in N-butyl-N-methylpiperidinium bis(trifluromethanesulfonyl) imide room temperature ionic liquids: Vibrational and theoretical studies
Published in Vibrational spectroscopy (01-11-2014)“…•Combined vibrational spectroscopic and DFT studies of piperidinium cation based ionic liquids is presented.•Variation in number and strength of H-bondings…”
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Development of In-situ Raman Diagnosis Technique of Eosinophil Esophagitis
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (15-01-2023)“…[Display omitted] •The viability of Raman spectroscopy for the live tissue with blood flow measured with 785 nm-excitation light showed a very weak signal due…”
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Co-ingestion with γ-cyclodextrin improves bioavailability of α-linolenic acid in Perilla frutescens seed oil
Published in Food hydrocolloids for health (01-12-2023)“…•Rat plasma 18:3n-3 was increased by co-ingestion of perilla oil with γ-CD.•Lipolysis in vitro revealed relatively strong resistance of perilla oil to…”
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Removal of hemolysis interference in serum Raman spectroscopy by multivariate curve resolution analysis for accurate classification of oral cancers
Published in Sensors & diagnostics (17-03-2023)“…Serum is an important biofluid that accurately reflects pathology and is used for early diagnosis of a wide range of diseases. Like most serological assays,…”
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Leucine pools in Escherichia coli biofilm discovered by Raman imaging
Published in Journal of Raman spectroscopy (15-11-2011)“…In structured communities of bacteria known as biofilms, a variety of biomolecules have been shown to play a unique role as signals and/or regulators in…”
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DNA Fingerprint Analysis of Raman Spectra Captures Global Genomic Alterations in Imatinib-Resistant Chronic Myeloid Leukemia: A Potential Single Assay for Screening Imatinib Resistance
Published in Cells (Basel, Switzerland) (22-09-2021)“…Monitoring the development of resistance to the tyrosine kinase inhibitor (TKI) imatinib in chronic myeloid leukemia (CML) patients in the initial chronic…”
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Visualizing wax ester fermentation in single Euglena gracilis cells by Raman microspectroscopy and multivariate curve resolution analysis
Published in Biotechnology for biofuels (22-05-2019)“…Global demand for energy is on the rise at a time when limited natural resources are fast depleting. To address this issue, microalgal biofuels are being…”
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Stable Isotope-Labeled Raman Imaging Reveals Dynamic Proteome Localization to Lipid Droplets in Single Fission Yeast Cells
Published in Chemistry & biology (21-11-2012)“…Lipid droplets have been hypothesized to be intimately associated with intracellular proteins. However, there is little direct evidence for both spatiotemporal…”
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Direct Visualization of Structurally Similar Polysaccharides in Single Yeast Cells in Vivo by Multivariate Analysis Assisted Raman Microspectroscopy
Published in The journal of physical chemistry. B (15-06-2023)“…The demand for functional food ingredients like β-glucan has risen enormously in recent times owing to its use in many fields including the food and beverage,…”
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Ag nanoparticle-embedded fish scales as SERS substrates for sensitive detection of forever chemical in real samples
Published in Applied surface science (15-11-2024)“…[Display omitted] •A flexible and cost-effective SERS sensor is created utilizing fish scales as a template.•The resulting SERS substrate exhibits notable…”
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