Search Results - "NOON, George P"

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart by Sharma, Saumya, Adrogue, Julia V., Golfman, Leonard, Uray, Ivan, Lemm, John, Youker, Keith, Noon, George P., Frazier, O. H., Taegtmeyer, Heinrich

“…ABSTRACT In animal models of lipotoxicity, accumulation of triglycerides within cardiomyocytes is associated with contractile dysfunction. However, whether…”
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Reversal of secondary pulmonary hypertension by axial and pulsatile mechanical circulatory support by Torre-Amione, Guillermo, MD, PhD, Southard, Robert E., MD, Loebe, Matthias M., MD, PhD, Youker, Keith A., PhD, Bruckner, Brian, MD, Estep, Jerry D., MD, Tierney, Megan, BS, Noon, George P., MD

“…Background Pulmonary hypertension associated with chronic congestive heart failure posses a significant risk of morbidity and death after heart…”
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Comparison of Hemodynamics in the Ascending Aorta Between Pulsatile and Continuous Flow Left Ventricular Assist Devices Using Computational Fluid Dynamics Based on Computed Tomography Images by Karmonik, Christof, Partovi, Sasan, Schmack, Bastian, Weymann, Alexander, Loebe, Matthias, Noon, George P., Piontek, Patrizia, Karck, Matthias, Lumsden, Alan B., Ruhparwar, Arjang

“…This study aims to investigate differences in hemodynamic conditions in the thoracic aorta for pulsatile and continuous‐flow left ventricular assist devices…”
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Regression of fibrosis and hypertrophy in failing myocardium following mechanical circulatory support by Bruckner, B A, Stetson, S J, Perez-Verdia, A, Youker, K A, Radovancevic, B, Connelly, J H, Koerner, M M, Entman, M E, Frazier, O H, Noon, G P, Torre-Amione, G

“…The cellular and structural changes that occur during long-term ventricular unloading leading to cardiac recovery are poorly understood. However, we have…”
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Increased Expression of Stem Cell Factor and Its Receptor After Left Ventricular Assist Device Support: A Potential Novel Target for Therapeutic Interventions in Heart Failure by Jahanyar, Jama, MD, PhD, Youker, Keith A., PhD, Torre-Amione, Guillermo, MD, PhD, Koerner, Michael M., MD, PhD, Bruckner, Brian, MD, Noon, George P., MD, Loebe, Matthias, MD, PhD

“…Background Left ventricular assist devices (LVADs) cause an influx of mast cells into the failing heart, but the underlying mechanism is unknown. This study…”
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Decorin-mediated Transforming Growth Factor-β Inhibition Ameliorates Adverse Cardiac Remodeling by Jahanyar, Jama, MD, PhD, Joyce, David L., MD, Southard, Robert E., MD, Loebe, Matthias, MD, PhD, Noon, George P., MD, Koerner, Michael M., MD, PhD, Torre-Amione, Guillermo, MD, PhD, Youker, Keith A., PhD

“…Background Implantation of a left ventricular assist device (LVAD) has been shown to induce regression of fibrosis in patients with congestive heart failure…”
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Somatic Chromosome Abnormalities in the Lungs of Patients with Pulmonary Arterial Hypertension by ALDRED, Micheala A, COMHAIR, Suzy A, COLDREN, Christopher D, VARELLA-GARCIA, Marileila, ASOSINGH, Kewal, WEILING XU, NOONS, George P, THISTLETHWAITE, Patricia A, TUDER, Rubin M, ERZURUM, Serpil C, GERACI, Mark W

“…Vascular remodeling in pulmonary arterial hypertension (PAH) involves proliferation and migration of endothelial and smooth muscle cells, leading to…”
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Mast Cell-Derived Cathepsin g: A Possible Role in The Adverse Remodeling of The Failing Human Heart by Jahanyar, Jama, M.D., Ph.D, Youker, Keith A., Ph.D, Loebe, Matthias, M.D., Ph.D, Assad-Kottner, Christian, M.D, Koerner, Michael M., M.D., Ph.D, Torre-Amione, Guillermo, M.D., Ph.D, Noon, George P., M.D

“…Background The role of cardiac mast cells (MCs) in the progression to heart failure has recently become increasingly evident. Cathepsin g is a neutrophil- and…”
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Recurrent Device Thrombi During Mechanical Circulatory Support With an Axial-flow Pump Is a Treatable Condition and Does Not Preclude Successful Long-term Support by Jahanyar, Jama, MD, PhD, Noon, George P., MD, Koerner, Michael M., MD, PhD, Youker, Keith A., PhD, Malaisrie, S. Chris, MD, Ngo, Uy Q., PA-C, Torre-Amione, Guillermo, MD, PhD, Loebe, Matthias, MD, PhD

“…The formation of pump thrombus after implantation of axial-flow ventricular assist devices has been described previously. We report a case of recurrent pump…”
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Alterations in coagulation after implantation of a pulsatile Novacor LVAD and the axial flow micromed DeBakey LVAD by Koster, Andreas, Loebe, Matthias, Hansen, Roland, Potapov, Evgenij V, Noon, George P, Kuppe, Hermann, Hetzer, Roland

“…Background. The MicroMed DeBakey left ventricular assist device (LVAD) is a chamber and valveless axial flow blood pump. We investigated parameters of the…”
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Inflammatory Response after Implantation of a Left Ventricular Assist Device: Comparison between the Axial Flow MicroMed DeBakey VAD and the Pulsatile Novacor Device by Loebe, Matthias, Koster, Andreas, Sänger, Stefan, Potapov, Evgenij V, Kuppe, Hermann, Noon, George P, Hetzer, Roland

“…The implantation of a ventricular assist device (VAD) is associated with a stimulation of the inflammatory system. We compared changes in the inflammatory…”
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Influence of LVAD Cannula Outflow Tract Location on Hemodynamics in the Ascending Aorta: A Patient-Specific Computational Fluid Dynamics Approach by Karmonik, Christof, Partovi, Sasan, Loebe, Matthias, Schmack, Bastian, Ghodsizad, Ali, Robbin, Mark R, Noon, George P, Kallenbach, Klaus, Karck, Matthias, Davies, Mark G, Lumsden, Alan B, Ruhparwar, Arjang

“…To develop a better understanding of the hemodynamic alterations in the ascending aorta, induced by variation of the cannula outflow position of the left…”
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Aprotinin for Primary Coronary Artery Bypass Grafting: A Multicenter Trial of Three Dose Regimens by Lemmer, John H., Dilling, Emery W., Morton, Jeremy R., Rich, Jeffrey B., Robicsek, Francis, Bricker, Donald L., Hantler, Charles B., Copeland, Jack G., Ochsner, John L., Daily, Pat O., Whitten, Charles W., Noon, George P., Maddi, Rosemarie

“…Background. High-dose aprotinin reduces transfusion requirements in patients undergoing coronary artery bypass grafting, but the safety and effectiveness of…”
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Integration of the computational fluid dynamics technique with MRI in aortic dissections by Karmonik, Christof, Partovi, Sasan, Davies, Mark G., Bismuth, Jean, Shah, Dipan J., Bilecen, Deniz, Staub, Daniel, Noon, George P., Loebe, Matthias, Bongartz, Georg, Lumsden, Alan B.

“…Short‐term and long‐term prognosis and their determining factors of Type III/Stanford B aortic dissections (TB‐AD), which separate the aorta distal at the…”
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Development and clinical application of the MicroMed DeBakey VAD by Noon, George P, Morley, Deborah, Irwin, Suellen, Benkowski, Robert

“…A miniaturized axial flow pump to provide left ventricular assistance has been developed. Such a device has the potential to address limitations of the larger…”
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Respect the History and Foresee the Future: Milestones of the International Society for Rotary Blood Pumps With Artificial Organs by Noon, George P., Loebe, Matthias, Motomura, Tadashi

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Current status of the MicroMed DeBakey Noon Ventricular Assist Device by Noon, George P, Loebe, Matthias

“…The HeartAttendant programs the controller and sets pump rpm and alarm thresholds. It collects and stores pump parameters when connected to the controller and…”
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Molecular remodelling of dystrophin in patients with end-stage cardiomyopathies and reversal in patients on assistance-device therapy by Vatta, Matteo, Stetson, Sonny J, Perez-Verdia, Alejandro, Entman, Mark L, Noon, George P, Torre-Amione, Guillermo, Bowles, Neil E, Towbin, Jeffrey A

“…Mutations that lead to disruption of cytoskeletal proteins have been recorded in patients with familial dilated cardiomyopathy. We postulated that changes in…”
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Contrast-enhanced Duplex surveillance after endovascular abdominal aortic aneurysm repair: Improved efficacy using a continuous infusion technique by Henao, Esteban A., Hodge, Megan D., Felkai, Deborah D., McCollum, Charles H., Noon, George P., Lin, Peter H., Lumsden, Alan B., Bush, Ruth L.

“…Currently, postoperative endoleak surveillance after endovascular aortic aneurysm repair (EVAR) is primarily done by computed tomography (CT). The purpose of…”
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Heterotopic heart transplantation: the United States experience by Jahanyar, Jama, Koerner, Michael M, Ghodsizad, Ali, Loebe, Matthias, Noon, George P

“…More than 3 decades have passed since the first heterotopic heart transplantation (HHT) was reported. Nowadays, this surgical technique is used rarely, and…”
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