Search Results - "NONAKA, Takahiro"

Analgesic characteristics of a newly developed α2δ ligand, mirogabalin, on inflammatory pain by Komatsu, Shuji, Nakamura, Shingo, Nonaka, Takahiro, Yamada, Toshihiko, Yamamoto, Tatsuo

“…Mirogabalin is a novel α2δ ligand approved in Japan for the treatment of peripheral neuropathic pain. However, the sites of action of α2δ ligands to produce…”
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Analysis and enhancement of risk management for ethnic differences in antineoplastic drugs in Japan by Uzu, Shinobu, Sato, Jun, Wakao, Rika, Nonaka, Takahiro

“…Background Risk management in the post-marketing phase is crucial to minimize health problems caused by drugs. Because ethnic factors may affect drug safety,…”
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Thoracoscopic Stand-Alone Left Atrial Appendectomy for Thromboembolism Prevention in Nonvalvular Atrial Fibrillation by Ohtsuka, Toshiya, MD, Ninomiya, Mikio, MD, Nonaka, Takahiro, MD, Hisagi, Motoyuki, MD, Ota, Takahiro, MD, Mizutani, Toru, MD

“…Objectives This study sought to evaluate thoracoscopic stand-alone left atrial appendectomy for thromboembolism prevention in nonvalvular atrial fibrillation…”
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Neuropeptide W, an endogenous NPBW1 and NPBW2 ligand, produced an analgesic effect via activation of the descending pain modulatory system during a rat formalin test by Nakamura, Shingo, Nonaka, Takahiro, Yoshida, Koji, Yamada, Toshihiko, Yamamoto, Tatsuo

“…Neuropeptide W (NPW) messenger ribonucleic acid (mRNA) and NPBW1 and/or NPBW2 mRNA are expressed in the descending pain inhibitory system. In the present…”
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Designation Products: Boron Neutron Capture Therapy for Head and Neck Carcinoma by Kanno, Hitoshi, Nagata, Hironori, Ishiguro, Akihiro, Tsuzuranuki, Satoshi, Nakano, Shintaro, Nonaka, Takahiro, Kiyohara, Koushin, Kimura, Toshinari, Sugawara, Akihiko, Okazaki, Yuzuru, Takae, Shinichi, Nakabayashi, Tetsuo, Arai, Hiroyuki, Suzuki, Hiroshi

“…The Japanese Ministry of Health, Labour and Welfare approved a drug called borofalan (10B), a treatment system, and a dose calculation program for boron…”
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Oral acetaminophen-induced spinal 5-hydroxytriyptamine release produces analgesic effects in the rat formalin test by Nakamura, Shingo, Nonaka, Takahiro, Komatsu, Shuji, Yamada, Toshihiko, Yamamoto, Tatsuo

“…The mechanism by which acetaminophen produces its analgesic effects is not fully understood. One possible mechanism is the activation of the spinal…”
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Structure and Function of Gli123 Involved in Mycoplasma mobile Gliding by Matsuike, Daiki, Tahara, Yuhei O, Nonaka, Takahiro, Wu, Heng Ning, Hamaguchi, Tasuku, Kudo, Hisashi, Hayashi, Yuuki, Arai, Munehito, Miyata, Makoto

“…Mycoplasma mobile is a fish pathogen that glides on solid surfaces by means of its own gliding machinery composed of internal and surface structures. In the…”
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Thoracoscopic stapler-and-loop technique for left atrial appendage closure in nonvalvular atrial fibrillation: Mid-term outcomes in 201 patients by Ohtsuka, Toshiya, Nonaka, Takahiro, Hisagi, Motoyuki, Ninomiya, Mikio, Masukawa, Ai, Ota, Takahiro

“…Left atrial appendage (LAA) closure can be an alternative to oral anticoagulation to prevent cardiogenic thromboembolisms in patients with nonvalvular atrial…”
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Risk of neutropenia in psoriasis patients prescribed anti-IL-23 antibody in comparison with anti-IL-17 antibody or adalimumab based on real-world data from the MID-NET ® in Japan by Okada, Yusuke, Kajiyama, Kazuhiro, Ishiguro, Chieko, Nonaka, Takahiro, Komaki, Tomomi, Kuga, Wataru, Komiyama, Noriyuki, Iguchi, Toyotaka, Horiuchi, Naoya, Uyama, Yoshiaki

“…To evaluate the risk of neutropenia during treatment with anti-IL-23 antibodies in patients with psoriasis. We conducted an observational study with cohort…”
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Descriptive Analysis for the Trend of Pharmacovigilance Planning in Risk Management Plans on New Drugs Approved During 2016-2019 by Kohama, Mei, Nonaka, Takahiro, Uyama, Yoshiaki, Ishiguro, Chieko

“…Japanese pharmaceutical authorities have conducted regulatory renovations of pharmacovigilance planning (PVP) since implementing new procedures for developing…”
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Transcatheter aortic valve implantation under lower activated clotting time in a patient with hemorrhagic gastric cancer: a case report by Mitsuta, Yuki, Oyoshi, Takafumi, Nonaka, Takahiro, Hirata, Naoyuki

“…Background Perioperative management of transcatheter aortic valve implantation (TAVI) in patients with a high risk of bleeding requires careful consideration…”
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Guidelines for clinical evaluation of anti‐cancer drugs by Minami, Hironobu, Kiyota, Naomi, Kimbara, Shiro, Ando, Yuichi, Shimokata, Tomoya, Ohtsu, Atsushi, Fuse, Nozomu, Kuboki, Yasutoshi, Shimizu, Toshio, Yamamoto, Noboru, Nishio, Kazuto, Kawakami, Yutaka, Nihira, Shin‐ichi, Sase, Kazuhiro, Nonaka, Takahiro, Takahashi, Hideaki, Komori, Yukiko, Kiyohara, Koshin

“…Clinical studies intended for regulatory approval must demonstrate the clinical benefits of the drug in a target population. Clinical development of a drug…”
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Garcin Syndrome Due to Meningeal Carcinomatosis from Gastric Cancer by Terasaki, Kei, Mizuno, Chiemi, Fujiishi, Shinsaku, Amioka, Shohei, Nonaka, Takahiro, Itani, Junichiro, Takahashi, Yusuke, Miura, Takahiro, Yasufuku, Tomoko, Oya, Hirohisa, Katayama, Takayuki, Okuda, Kotaro, Matsumoto, Junko, Mitsumoto, Yasuhide, Sawai, Naoki, Mizuno, Masayuki, Shima, Toshihide, Okanoue, Takeshi

“…A 58-year-old woman presented to our hospital with complaints of dysphagia. Esophagogastroduodenoscopy showed an esophagogastric junction tumor with multiple…”
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Increased risk of hypocalcemia with decreased kidney function in patients prescribed bisphosphonates based on real-world data from the MID-NET ® in Japan: a new-user cohort study by Hasegawa, Tomoaki, Komamine, Maki, Ishiguro, Chieko, Motomura, Haruka, Kajiyama, Kazuhiro, Nonaka, Takahiro, Nakazato, Yuki, Kimura, Ryota, Maniwa, Harumi, Iguchi, Toyotaka, Horiuchi, Naoya, Uyama, Yoshiaki

“…In the post-marketing stage, cases of hypocalcemia associated with bisphosphonate preparations (BPs) have been reported in patients with decreased kidney…”
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Assessing the Risk of Decrease in Kidney Function in Patients Prescribed Direct-Acting Antivirals for Hepatitis C Utilizing the MID-NET ® Medical Information Database Network in Japan by Hasegawa, Tomoaki, Sawada, Sono, Ishiguro, Chieko, Ando, Takashi, Kobayashi, Kanae, Komiyama, Noriyuki, Iguchi, Toyotaka, Nonaka, Takahiro, Uyama, Yoshiaki

“…An association between kidney disease and direct-acting antivirals against hepatitis C (DAAs) has been suggested, however the warning on the package insert…”
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Statistical testing strategies for assessing treatment efficacy and marker accuracy in phase III trials by Nonaka, Takahiro, Igeta, Masataka, Matsui, Shigeyuki

“…Summary When a candidate predictive marker is available, but evidence on its predictive ability is not sufficiently reliable, all‐comers trials with marker…”
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A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA by Nonaka, Takahiro, Yamada, Toshihiko, Ishimura, Tatsuhiro, Zuo, Daiying, Moffett, John R, Neale, Joseph H, Yamamoto, Tatsuo

“…N-acetylaspartylglutamate (NAAG) is the third most prevalent and widely distributed neurotransmitter in the mammalian nervous system. NAAG activates a group II…”
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A Mass Filling the Right Atrium: Primary Cardiac Rhabdomyosarcoma by Kimura, Akihisa, Tsuji, Masaki, Isogai, Toshiaki, Nagata, Kenichiro, Kato, Ken, Hisagi, Motoyuki, Nonaka, Takahiro, Ninomiya, Mikio, Kiriu, Takahiro, Tanaka, Hiroyuki, Tejima, Tamotsu

“…A 43-year-old woman presented with worsening shortness of breath and lower-extremity edema. Echocardiography and computed tomography showed obstruction of…”
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Thoracoscopic infrared ablation to create a box lesion as a treatment for atrial fibrillation by Kubota, Hiroshi, Ohtsuka, Toshiya, Ninomiya, Mikio, Nonaka, Takahiro, Hisagi, Motoyuki, Endo, Hidehito, Minegishi, Sachito, Tsuchiya, Hiroshi, Inaba, Yusuke

“…Creating a box lesion in the posterior wall of the left atrium from the epicardial side of the beating heart remains a challenge. Although a transmural lesion…”
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Triskelion Structure of the Gli521 Protein, Involved in the Gliding Mechanism of Mycoplasma mobile by NONAKA, Takahiro, ADAN-KUBO, Jun, MIYATA, Makoto

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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