Search Results - "NOLAN, P. M"

Social jetlag, obesity and metabolic disorder: investigation in a cohort study by Parsons, M J, Moffitt, T E, Gregory, A M, Goldman-Mellor, S, Nolan, P M, Poulton, R, Caspi, A

“…Background: Obesity is one of the leading causes of preventable death worldwide. Circadian rhythms are known to control both sleep timing and energy…”
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Carotenoid Accumulation Strategies for Becoming a Colourful House Finch: Analyses of Plasma and Liver Pigments in Wild Moulting Birds by McGraw, K. J., Nolan, P. M., Crino, O. L.

“…1. Male House Finches (Carpodacus mexicanus) colour their sexually selected plumage with carotenoid pigments, and there has been much interest in the factors…”
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Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway by Killick, R, Ribe, E M, Al-Shawi, R, Malik, B, Hooper, C, Fernandes, C, Dobson, R, Nolan, P M, Lourdusamy, A, Furney, S, Lin, K, Breen, G, Wroe, R, To, A W M, Leroy, K, Causevic, M, Usardi, A, Robinson, M, Noble, W, Williamson, R, Lunnon, K, Kellie, S, Reynolds, C H, Bazenet, C, Hodges, A, Brion, J-P, Stephenson, J, Paul Simons, J, Lovestone, Simon

“…Although the mechanism of Aβ action in the pathogenesis of Alzheimer’s disease (AD) has remained elusive, it is known to increase the expression of the…”
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A retroviral Gene Trap Insertion into the Histone 3.3A Gene Causes Partial Neonatal Lethality, Stunted Growth, Neuromuscular Deficits and Male Sub-fertility in Transgenic Mice by Couldrey, Christine, Carlton, Mark B.L., Nolan, Patrick M., Colledge, William H., Evans, Martin J.

“…Spermatogenesis is a complex developmental process involving cell division and differentiation. Approximately half of all sterile males have defects in…”
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Reaching and grasping phenotypes in the mouse ( Mus musculus ): A characterization of inbred strains and mutant lines by Tucci, V, Achilli, F, Blanco, G, Lad, H.V, Wells, S, Godinho, S, Nolan, P.M

“…Abstract Skilled movements, such as reaching and grasping, have classically been considered as originating in the primate lineage. For this reason, the use of…”
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Genetic and molecular analysis of the central and peripheral circadian clockwork of mice by Maywood, E S, O'Neill, J S, Reddy, A B, Chesham, J E, Prosser, H M, Kyriacou, C P, Godinho, S I H, Nolan, P M, Hastings, M H

“…A hierarchy of interacting, tissue-based clocks controls circadian physiology and behavior in mammals. Preeminent are the suprachiasmatic nuclei (SCN): central…”
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A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies by Banks, G, Lassi, G, Hoerder-Suabedissen, A, Tinarelli, F, Simon, M M, Wilcox, A, Lau, P, Lawson, T N, Johnson, S, Rutman, A, Sweeting, M, Chesham, J E, Barnard, A R, Horner, N, Westerberg, H, Smith, L B, Molnár, Z, Hastings, M H, Hirst, R A, Tucci, V, Nolan, P M

“…Microtubule severing enzymes implement a diverse range of tissue-specific molecular functions throughout development and into adulthood. Although microtubule…”
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Screening for novel ENU‐induced rhythm, entrainment and activity mutants by Bacon, Y., Ooi, A., Kerr, S., Shaw‐Andrews, L., Winchester, L., Breeds, S., Tymoska‐Lalanne, Z., Clay, J., Greenfield, A. G., Nolan, P. M.

“…Chemical mutagenesis has provided an opportunity to develop and expand the repertoire of behavioural mutants for gene function studies. With this in mind, we…”
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Intraventricular infusions of anti-neural cell adhesion molecules in a discrete posttraining period impair consolidation of a passive avoidance response in the rat by Doyle, E, Nolan, P M, Bell, R, Regan, C M

“…Intraventricular infusions of anti-neural cell adhesion molecule (anti-NCAM) are demonstrated to inhibit consolidation of a passive avoidance response when…”
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Mouse Mutagenesis—Systematic Studies of Mammalian Gene Function by Brown, Steve D. M., Nolan, Patrick M.

“…The mouse will play a pivotal role in mammalian gene function studies as we enter the post-genomics era. The challenge is to develop systematic, genome-wide…”
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Sex, size, and plumage redness predict house finch survival in an epidemic by Nolan, Paul M., Hill, Geoffrey E., Stoehr, Andrew M.

“…is a well–known disease of poultry but until 1994 had not been observed in passerine birds. From 1994 to 1996, tens of millions of house finches (…”
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Hippocampal NCAM180 transiently increases sialylation during the acquisition and consolidation of a passive avoidance response in the adult rat by Doyle, E, Nolan, P M, Bell, R, Regan, C M

“…Synaptic connectivity change is a consistent anatomical feature of memory formation and the possibility that this is mediated by a replay of neurodevelopmental…”
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Sleep‐like behavior and 24‐h rhythm disruption in the Tc1 mouse model of Down syndrome by Heise, I., Fisher, S. P., Banks, G. T., Wells, S., Peirson, S. N., Foster, R. G., Nolan, P. M.

“…Down syndrome is a common disorder associated with intellectual disability in humans. Among a variety of severe health problems, patients with Down syndrome…”
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Random Mutagenesis Screen for Dominant Behavioral Mutations in Mice by Nolan, P.M., Kapfhamer, D., Bućan, M.

“…Large-scale mutagenesis and screening for altered phenotypes have been used effectively in many (lower) model organisms to identify mutations in genes that…”
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Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy by ISAACS, A. M, DAVIES, K. E, FISHER, E. M. C, BOUZYK, M. M, POTTER, A, MASIH, M, WALSH, F. S, SIMS, M. A, DONCASTER, K. E, PARSONS, C. A, MARTIN, J, BROWN, S. D. M, HUNTER, A. J, RASTAN, S, SPURR, N. K, GRAY, L. C, NOLAN, P. M, VIZOR, L, PETERS, J, GALE, D. G, KELSELL, D. P, LATHAM, I. D, CHASE, J. M

“…Mouse mutants have a key role in discerning mammalian gene function and modelling human disease; however, at present mutants exist for only 1-2% of all mouse…”
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Towards new models of disease and physiology in the neurosciences: the role of induced and naturally occurring mutations by HUNTER, A. J, NOLAN, P. M, BROWN, S. D. M

“…There is a dearth of good mouse models for central nervous system (CNS) disorders. However, the development of gene-targeted technology and the recognition of…”
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Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse by Curtin, John A., Quint, Elizabeth, Tsipouri, Vicky, Arkell, Ruth M., Cattanach, Bruce, Copp, Andrew J., Henderson, Deborah J., Spurr, Nigel, Stanier, Philip, Fisher, Elizabeth M., Nolan, Patrick M., Steel, Karen P., Brown, Steve D.M., Gray, Ian C., Murdoch, Jennifer N.

“…We identified two novel mouse mutants with abnormal head-shaking behavior and neural tube defects during the course of independent ENU mutagenesis experiments…”
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Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19 by Gåfvels, M E, Paavola, L G, Boyd, C O, Nolan, P M, Wittmaack, F, Chawla, A, Lazar, M A, Bucan, M, Angelin, B O, Strauss, 3rd, J F

“…We report the cloning of a complementary DNA for the mouse homolog of the very low density lipoprotein (VLDL)/apolipoprotein-E receptor (VLDLR), the deduced…”
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Heterozygosity Mapping of Partially Congenic Lines: Mapping of a Semidominant Neurological Mutation, Wheels (Whl), on Mouse Chromosome 4 by Nolan, P. M, Sollars, P. J, Bohne, B. A, Ewens, W. J, Pickard, G. E, Bucan, M

“…We identified a semidominant, chemically induced, mouse mutation with a complex array of abnormal behaviors including bidirectional circling and hyperactivity,…”
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Characterization of Mycoplasma gallisepticum infection in captive house finches (Carpodacus mexicanus) in 1998 by Roberts, S.R, Nolan, P.M, Hill, G.E

“…Since 1995, the epidemic of mycoplasmal conjunctivitis in eastern house finches has affected the Auburn, AL, house finch population. To better characterize the…”
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