Search Results - "NOH, YUN HEE"
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Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate
Published in Developmental dynamics (01-11-2002)“…Early during development, one of the first indications that lymphangiogenesis has begun is the polarized expression of the homeobox gene Prox1 in a…”
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2
Assessment of the safety and efficacy of an attenuated live vaccine based on highly virulent genotype 2b porcine epidemic diarrhea virus in nursing piglets
Published in Veterinary microbiology (01-04-2019)“…•Attenuated G2b PEDV strain S DEL5/ORF3 was pioneered to develop an MLV vaccine.•S DEL5/ORF3 did not revert to virulence after successive back passages in…”
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3
Comparison of the pathogenicity of porcine reproductive and respiratory syndrome virus (PRRSV)-1 and PRRSV-2 in pregnant sows
Published in Archives of virology (01-02-2022)“…To date, few studies related to the evaluation of the pathogenicity of different PRRSV isolates using a reproductive model have been undertaken, and the main…”
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4
Molecular characteristics and pathogenic assessment of porcine epidemic diarrhoea virus isolates from the 2018 endemic outbreaks on Jeju Island, South Korea
Published in Transboundary and emerging diseases (01-09-2019)“…Since the 2013–2014 incursion of the virulent G2b porcine epidemic diarrhoea virus (PEDV) pandemic strains in South Korea, frequent moderate‐scale regional…”
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5
Role of the Mixed-Lineage Protein Kinase Pathway in the Metabolic Stress Response to Obesity
Published in Cell reports (Cambridge) (29-08-2013)“…Saturated free fatty acid (FFA) is implicated in the metabolic response to obesity. In vitro studies indicate that FFA signaling may be mediated by the…”
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6
Generation and protective efficacy of a cold-adapted attenuated genotype 2b porcine epidemic diarrhea virus
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-07-2019)“…The recent emergence and re-emergence of porcine epidemic diarrhea virus (PEDV) underscore the urgent need for the development of novel, safe, and effective…”
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7
Evaluation of the Cross-Protective Efficacy of a Chimeric PRRSV Vaccine against Two Genetically Diverse PRRSV2 Field Strains in a Reproductive Model
Published in Vaccines (Basel) (31-10-2021)“…Despite the routine use of porcine reproductive and respiratory syndrome (PRRS)-modified live vaccines, serious concerns are currently being raised due to…”
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8
Phenotypic and genotypic analyses of an attenuated porcine reproductive and respiratory syndrome virus strain after serial passages in cultured porcine alveolar macrophages
Published in Journal of veterinary science (Suwŏn-si, Korea) (01-05-2018)“…Porcine reproductive and respiratory syndrome virus (PRRSV) is a globally ubiquitous swine viral pathogen that causes major economic losses worldwide. We…”
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9
Improvement of β-cell function after achievement of optimal glycaemic control via long-term continuous subcutaneous insulin infusion therapy in non-newly diagnosed type 2 diabetic patients with suboptimal glycaemic control
Published in Diabetes/metabolism research and reviews (01-09-2013)“…Background Achieving euglycaemia by continuous subcutaneous insulin infusion (CSII) therapy alone has been shown to restore β‐cell function in patients with…”
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10
Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats
Published in Journal of hypertension (01-04-2007)“…In deoxycorticosterone acetate (DOCA)-salt hypertensive rats, altered reactivity of blood vessels to vasoactive agonists is frequently associated with an…”
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11
Heterogeneity in liver histopathology is associated with GSK-3β activity and mitochondrial dysfunction in end-stage diabetic rats on differential diets
Published in BMB reports (28-02-2020)“…While liver histopathology is heterogeneous in diabetes, the underlying mechanisms remain unclear. We investigated whether glycemic variation resulting from…”
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12
Euglycemia in Diabetic Rats Leads to Reduced Liver Weight via Increased Autophagy and Apoptosis through Increased AMPK and Caspase-3 and Decreased mTOR Activities
Published in Journal of diabetes research (01-01-2015)“…Euglycemia is the ultimate goal in diabetes care to prevent complications. However, the benefits of euglycemia in type 2 diabetes are controversial because…”
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13
Genetic characteristics, pathogenicity, and immunogenicity associated with cell adaptation of a virulent genotype 2b porcine epidemic diarrhea virus
Published in Veterinary microbiology (01-08-2017)“…•A virulent G2b PEDV strain KNU-141112 was subjected to Vero cell culture passage.•Deletions (DEL) in S and ORF3 of KNU-141112 at high passage levels were…”
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14
Differential gene expression in retinoic acid-induced differentiation of acute promyelocytic leukemia cells, NB4 and HL-60 cells
Published in Biochemical and biophysical research communications (06-09-2002)“…Acute promyelocytic leukemia (APL) is characterized by a specific chromosome translocation t(15;17), which results in the fusion of the promyelocytic leukemia…”
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15
Integrative Meta-Analysis of Multiple Gene Expression Profiles in Acquired Gemcitabine-Resistant Cancer Cell Lines to Identify Novel Therapeutic Biomarkers
Published in Asian Pacific journal of cancer prevention : APJCP (2015)“…In molecular-targeted cancer therapy, acquired resistance to gemcitabine is a major clinical problem that reduces its effectiveness, resulting in recurrence…”
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16
An N-Terminal 80 kDa Recombinant Fragment of Human Thrombospondin-2 Inhibits Vascular Endothelial Growth Factor Induced Endothelial Cell Migration In Vitro and Tumor Growth and Angiogenesis In Vivo
Published in Journal of investigative dermatology (01-12-2003)“…We have previously shown that stable overexpression of the thrombospondin-2 (TSP-2) gene inhibited the tumor growth and angiogenesis of human squamous cell…”
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17
Improvement of cardiovascular risk factors in patients with type 2 diabetes after long-term continuous subcutaneous insulin infusion
Published in Diabetes/metabolism research and reviews (01-07-2008)“…Background The effects of long‐term continuous subcutaneous insulin infusion (CSII) on cardiovascular risk factors such as hyperglycaemia, dyslipidaemia, and…”
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18
Efficacy of Porcine Epidemic Diarrhea Vaccines: A Systematic Review and Meta-Analysis
Published in Vaccines (Basel) (02-11-2020)“…Porcine epidemic diarrhea (PED) is a devastating disease that causes considerable economic damage to the global pig industry. Although the causative agent, the…”
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Pathological Evaluation of Porcine Circovirus 2d (PCV2d) Strain and Comparative Evaluation of PCV2d and PCV2b Inactivated Vaccines against PCV2d Infection in a Specific Pathogen-Free (SPF) Yucatan Miniature Pig Model
Published in Vaccines (Basel) (05-09-2022)“…Porcine circovirus type 2 (PCV2) is an economically important swine pathogen that causes porcine circovirus-associated diseases (PCVADs). The objective of this…”
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20
Effects of hydrogen peroxide on voltage-dependent K + currents in human cardiac fibroblasts through protein kinase pathways
Published in The Korean journal of physiology & pharmacology (01-01-2016)“…Human cardiac fibroblasts (HCFs) have various voltage-dependent $K^+$ channels (VDKCs) that can induce apoptosis. Hydrogen peroxide ($H_2O_2$) modulates VDKCs…”
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