Search Results - "NODA, Yukihiro"
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Phencyclidine animal models of schizophrenia: Approaches from abnormality of glutamatergic neurotransmission and neurodevelopment
Published in Neurochemistry international (01-07-2007)“…In humans, phencyclidine (PCP), a non-competitive N-methyl- d-aspartate (NMDA) receptor antagonist, reproduces a schizophrenia-like psychosis including…”
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A Reactive Metabolite of Clozapine Induces Hematopoietic Toxicity in HL-60 Cells Undergoing Granulocytic Differentiation through Its Effect on Glutathione Metabolism
Published in Biological & pharmaceutical bulletin (01-09-2022)“…Clozapine is an atypical antipsychotic with several advantages over conventional antipsychotics, in addition to its well-known efficacy in treatment-resistant…”
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Memantine ameliorates the impairment of social behaviors induced by a single social defeat stress as juveniles
Published in Neuropharmacology (01-10-2022)“…Clinically, juveniles are more sensitive to stress than adults, and exposure to stress as juveniles prolongs psychiatric symptoms and causes treatment…”
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Behavioral Phenotypes in Schizophrenic Animal Models With Multiple Combinations of Genetic and Environmental Factors
Published in Journal of Pharmacological Sciences (2013)“…Schizophrenia is a multifactorial psychiatric disorder in which both genetic and environmental factors play a role. Genetic [e.g., Disrupted-in-schizophrenia 1…”
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Unexpected cosolvency of water on poly(propylene glycol) in hydrophobic ionic liquid
Published in Colloid and polymer science (01-10-2019)“…By addition of small amount of water, lower critical solution temperature (LCST)–type cloud point (CP) of poly(propylene glycol) (PPG) in hydrophobic ionic…”
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Multiple nicotinic acetylcholine receptor subtypes regulate social or cognitive behaviors in mice repeatedly administered phencyclidine
Published in Behavioural brain research (25-06-2021)“…•Repeated PCP administration induces some psychobehavioral impairments in mice.•PCP also induces changes in the expression of nAChR subunits in the PFC or…”
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Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits
Published in Neuron (Cambridge, Mass.) (25-02-2010)“…Adult brain function and behavior are influenced by neuronal network formation during development. Genetic susceptibility factors for adult psychiatric…”
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Blonanserin ameliorates social deficit through dopamine-D3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia
Published in Neurochemistry international (01-09-2019)“…Blonanserin differs from other antipsychotic drugs, such as risperidone and olanzapine, and exhibits a higher affinity for dopamine-D2/3 receptors than for…”
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Involvement of PKCβI-SERT activity in stress vulnerability of mice exposed to twice-swim stress
Published in Neuroscience research (01-10-2021)“…•Mice exposed to twice-swim stress had impaired social behaviors.•PKC activator ameliorated the impairment of social behaviors in twice-stressed mice.•PKCβI…”
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MAGE-D1 regulates expression of depression-like behavior through serotonin transporter ubiquitylation
Published in The Journal of neuroscience (28-03-2012)“…The ubiquitin-proteasome system (UPS) controls the stability of most cellular proteins. The polymorphism of UPS-related genes is associated with major…”
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Adolescent stress leads to glutamatergic disturbance through dopaminergic abnormalities in the prefrontal cortex of genetically vulnerable mice
Published in Psychopharmacology (01-10-2017)“…Background Stress during the adolescent period influences postnatal maturation and behavioral patterns in adulthood. Adolescent stress-induced molecular and…”
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Thoracic endovascular aortic repair of a ruptured acute type B aortic dissection presenting with right hemothorax: a case report and review of the literature
Published in General thoracic and cardiovascular surgery (01-10-2021)“…Ruptured acute type B aortic dissection is a life-threatening condition with a high mortality rate. Right hemothorax secondary to this condition is extremely…”
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Involvement of Allosteric Effect and KCa Channels in Crosstalk between β2-Adrenergic and Muscarinic M2 Receptors in Airway Smooth Muscle
Published in International journal of molecular sciences (09-07-2018)“…To advance the development of bronchodilators for asthma and chronic obstructive pulmonary disease (COPD), this study was designed to investigate the mechanism…”
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Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood
Published in Neuroscience research (01-07-2009)“…It has been reported that viral infection in the first and second trimesters of pregnancy in humans increases the risk of subsequently developing…”
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Early postnatal inhibition of GLAST causes abnormalities of psychobehaviors and neuronal morphology in adult mice
Published in Neurochemistry international (01-11-2021)“…The importance of glutamate transporters in learning, memory, and emotion remains poorly understood; hence, in the present study, we investigated whether…”
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Involvement of nicotinic acetylcholine receptors in behavioral abnormalities and psychological dependence in schizophrenia-like model mice
Published in European neuropsychopharmacology (01-12-2020)“…•Repeated PCP administration induces some psychobehavioral impairments in mice.•PCP also induces similar changes in expression of α7 nAChR subunit as seen in…”
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Differential effects of physical activity and sleep duration on cognitive function in young adults
Published in Journal of sport and health science (01-04-2018)“…Although exercise and sleep duration habits are associated with cognitive function, their beneficial effects on cognitive function remain unclear. We aimed to…”
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The involvement of brain-derived neurotrophic factor in 3,4-methylenedioxymethamphetamine-induced place preference and behavioral sensitization
Published in Behavioural brain research (30-06-2017)“…3,4-Methylenedioxymethamphetamine (MDMA) is known to induce dependence and psychosis in humans. Brain-derived neurotrophic factor (BDNF) is involved in the…”
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Promoting Appropriate Use of Medications by “Lectures and Practices Regarding Medicine” for the Regional Community Residents
Published in YAKUGAKU ZASSHI (01-01-2023)“…We held lectures and practices for the regional community residents with the aim of promoting appropriate use of medications. To evaluate the usefulness of our…”
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Mice deficient in protein tyrosine phosphatase receptor type Z (PTPRZ) show reduced responsivity to methamphetamine despite an enhanced response to novelty
Published in PloS one (20-08-2019)“…Methamphetamine (METH), a commonly abused drug, elevates extracellular dopamine (DA) levels by inducing DA efflux through the DA transporter (DAT). Emerging…”
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