Search Results - "NOBLE, M. I. M"

What is the mechanism of flow-mediated arterial dilatation by Markos, Farouk, Ruane O'Hora, Therese, Noble, Mark IM

“…Summary The present review attempts to explain the controversies concerning the mechanism of shear stress‐mediated arterial dilatation, commonly called…”
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Hypothesis: arterial glycocalyx dysfunction is the first step in the atherothrombotic process by Noble, M.I.M., Drake-Holland, A.J., Vink, H.

“…We present evidence that the 0.5 µm thick gel layer, lining the inner wall of healthy blood vessels, the glycocalyx, is the first line of defence against…”
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Differential inhibition by hyperglycaemia of shear stress- but not acetylcholine-mediated dilatation in the iliac artery of the anaesthetized pig by Kelly, R., Ruane‐O'Hora, T., Noble, M. I. M., Drake‐Holland, A. J., Snow, H. M.

“…Clinical hyperglycaemia affects vascular endothelial function, but the effect on shear stress-induced arterial dilatation has not yet been established. We…”
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Dependence of smooth muscle tone upon pulsatility in the iliac artery of the anaesthetised pig by Markos, F., Ruane O’Hora, T., Wainwright, C. L., Noble, M. I. M.

“…The aim of the study was to examine features of the myogenic response of a conduit artery to the presence and absence of pulsatile pressure. The iliac arteries…”
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Effect of plasma homocysteine concentration on early and late events in patients with acute coronary syndromes by STUBBS, P. J, AL-OBAIDI, M. K, CONROY, R. M, COLLINSON, P. O, GRAHAM, I. M, NOBLE, M. I. M

“…Although a raised plasma homocysteine is a risk factor for vascular disease, it is not known whether it is associated with an adverse cardiac outcome in…”
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Dilatation in the femoral vascular bed does not cause retrograde relaxation of the iliac artery in the anaesthetized pig by Halcox, Julian P.J

“…We tested the hypothesis that dilatation of a feeding artery may be elicited by transmission of a signal through the tissue of the arterial wall from a…”
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Myocardial contractility is not constant during spontaneous atrial fibrillation in patients by BROOKES, C. I. O, WHITE, P. A, STAPLES, M, OLDERSHAW, P. J, REDINGTON, A. N, COLLINS, P. D, NOBLE, M. I. M

“…The variation in stroke volume and pulse pressure characteristic of atrial fibrillation is usually ascribed to time-dependent ventricular filling, implying a…”
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A potassium ion myth? Musings on Nernst, normal and pathological electrics and all causes of cell death by Noble, Mark I M

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Acute and convalescent changes in plasma homocysteine concentrations in acute coronary syndromes by Al-Obaidi, M K, Stubbs, P J, Amersey, R, Noble, M I M

“…BACKGROUND Raised plasma homocysteine is a risk factor for coronary artery disease. Patients with myocardial infarction or unstable angina show greater…”
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Regional sympathetic denervation affects the relation between canine local myocardial blood flow and oxygen consumption by Alders, David J. C., Cornelussen, Richard N., Prinzen, Frits W., Specht, Patricia A. C., Noble, Mark I. M., Drake‐Holland, Angela J., De Kanter, Frans J. J., Van Beek, Johannes H. G. M.

“…Myocardial blood flow and oxygen consumption are heterogeneously distributed. Perfusion and myocardial oxygen consumption are closely correlated in the normal…”
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Responses of iliac conduit artery and hindlimb resistance vessels to luminal hyperfructosemia in the anaesthetized pig by Ruane-O'Hora, T., Edge, D., Shortt, C. M., Markos, F., Noble, M. I. M.

“…Aims High fructose levels are found in diabetes mellitus, associated with high corn syrup diets, and have been claimed to cause hypertension. As the direct…”
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Intraluminal hyperglycaemia causes conduit and resistance artery dilatation and inhibits vascular autoregulation in the anaesthetised pig by Ruane-O'Hora, Therese, Shortt, Christine M, Edge, Deirdre, Markos, Farouk, Noble, Mark I M

“…The effect of intraluminal hyperglycaemia was investigated in the iliac artery of 11 anaesthetised pigs. Following isolation of a test segment, hyperglycaemic…”
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Comparison between the Sarcomere Length-Force Relations of Intact and Skinned Trabeculae from Rat Right Ventricle: Influence of Calcium Concentrations on These Relations by Kentish, Jonathan C, ter Keurs, Henk E.D.J, Ricciardi, Lucio, Bucx, Jeroen J.J, Noble, Mark I.M

“…To investigate the extent to which the properties of the cardiac myofibrils contribute to the length-force relation of cardiac muscle, we determined the…”
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Rediscovery of Otto Frank's contribution to science by Kuhtz-Buschbeck, Johann P., Drake-Holland, Angela, Noble, Mark I.M., Lohff, Brigitte, Schaefer, Jochen

“…In the late 19th century, German physiologist Otto Frank (1865–1944) embarked on a near life-long research program of laying down the mathematical,…”
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Electro‐physics‐iology revised by Noble, Mark I. M.

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Response to Eisner and Miller by Noble, Mark I. M.

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Platelet 5-hydroxytryptamine is decreased in a preliminary group of depressed patients receiving the 5-hydroxytryptamine re-uptake inhibiting drug fluoxetine by Menys, V C, Smith, C C, Lewins, P, Farmer, R D, Noble, M I

“…1. In view of the importance of 5-hydroxytryptamine in coronary thrombosis, we wanted to know whether a potentially protective decrease in platelet…”
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Should we now abandon the low-salt diet? by Drake-Holland, A.J., Noble, M.I.M.

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Significance of an index of insulin resistance on admission in non-diabetic patients with acute coronary syndromes by Stubbs, P J, Alaghband-Zadeh, J, Laycock, J F, Collinson, P O, Carter, G D, Noble, M I M

“…BACKGROUND Insulin resistance is associated with ischaemic heart disease and has been proposed as a risk factor for subsequent myocardial infarction. AIM To…”
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Increased urinary albumin and retinol-binding protein in type I diabetes. A study of identical twins by DUBREY, S. W, BEETHAM, R, MILES, J, NOBLE, M. I. M, ROWE, R, LESLIE, R. D. G

“…Increased urinary albumin and retinol-binding protein in type I diabetes. A study of identical twins. S W Dubrey , R Beetham , J Miles , M I Noble , R Rowe and…”
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