Search Results - "NISHIZAWA, Kenji"
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Universal glass-forming behavior of in vitro and living cytoplasm
Published in Scientific reports (09-11-2017)“…Physiological processes in cells are performed efficiently without getting jammed although cytoplasm is highly crowded with various macromolecules. Elucidating…”
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A retrospective study of the risk factors for linezolid-induced thrombocytopenia and anemia
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-08-2016)“…Abstract Myelosuppression is major treatment-related adverse events of linezolid therapy and result in treatment termination in some cases. We aimed to…”
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Optimal trough concentration of voriconazole with therapeutic drug monitoring in children: A systematic review and meta-analysis
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-02-2021)“…This systematic review and meta-analysis was designed to determine the optimal trough concentration of voriconazole for children with invasive fungal…”
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Successful laparoscopic management of acute abdominal pain due to spontaneous rupture of subserosal vessels overlying a uterine fibroid: a case report and surgical video
Published in BMC women's health (23-09-2022)“…Background Acute abdomen comprises several emergencies. Hemoperitoneum associated with uterine fibroids, which can present as acute abdominal pain, is rare and…”
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Favorable Effects of Voriconazole Trough Concentrations Exceeding 1 μg/mL on Treatment Success and All-Cause Mortality: A Systematic Review and Meta-Analysis
Published in Journal of fungi (Basel) (16-04-2021)“…This systematic review and meta-analysis examined the optimal trough concentration of voriconazole for adult patients with invasive fungal infections. We used…”
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Feedback-tracking microrheology in living cells
Published in Science advances (01-09-2017)“…Living cells are composed of active materials, in which forces are generated by the energy derived from metabolism. Forces and structures self-organize to…”
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Apoptotic Effects of a Thioether Analog of Vitamin K3 in a Human Leukemia Cell Line
Published in International journal of toxicology (01-12-2021)“…Research suggests that thioether analogs of vitamin K3 (VK3) can act to preserve the phosphorylation of epidermal growth factor receptors by blocking enzymes…”
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Study of the compatibility of oral magnesium oxide preparations sold in Japan with the ICH-Q3D guideline for elemental impurities
Published in Drug Discoveries & Therapeutics (21-11-2021)“…Magnesium oxide has been widely used as an antacid and constipation remedy. Currently in Japan, magnesium oxide preparations manufactured by five medical…”
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A new carbapenem drug dosage metric for carbapenem usage and correlation with carbapenem resistance of Pseudomonas aeruginosa
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-12-2018)“…The emergence and dissemination of antimicrobial resistance is a worldwide problem. Inappropriate antimicrobial use contributes to this resistance, and several…”
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The correlation between plasma aprepitant concentration and antiemetic effect in Japanese gastric or esophageal cancer patients
Published in International journal of clinical oncology (01-06-2015)“…Background Chemotherapy-induced nausea and vomiting (CINV) are significant problems in cancer patients, but a correlation between plasma aprepitant…”
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Rapid, simple, and clinically applicable high-performance liquid chromatography method for clinical determination of plasma colistin concentrations
Published in Journal of pharmaceutical health care and sciences (20-08-2018)“…Since both the antibacterial effects and common adverse effects of colistin are concentration-dependent, determination of the most appropriate dosage regimen…”
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Activity-dependent glassy cell mechanics Ⅰ: Mechanical properties measured with active microrheology
Published in Biophysical journal (16-05-2023)“…Active microrheology was conducted in living cells by applying an optical-trapping force to vigorously fluctuating tracer beads with feedback-tracking…”
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Activity-dependent glassy cell mechanics II: Nonthermal fluctuations under metabolic activity
Published in Biophysical journal (21-11-2023)“…The glassy cytoplasm, crowded with bio-macromolecules, is fluidized in living cells by mechanical energy derived from metabolism. Characterizing the living…”
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Artificial neural network modeling to predict the plasma concentration of aminoglycosides in burn patients
Published in Biomedicine & pharmacotherapy (01-05-2004)“…The goal was to use an artificial neural network model to predict the plasma concentration of aminoglycosides in burn patients and identify patients whose…”
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Two-Point Optical Manipulation of Cell Junctions in the Early Epithelium of the Drosophila Embryo
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Laser manipulation is widely used to study mechanics from the molecular to the tissue scale. We implemented optical tweezers to directly manipulate single…”
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Two-point optical manipulation reveals mechanosensitive remodeling of cell-cell contacts in vivo
Published in Proceedings of the National Academy of Sciences - PNAS (28-03-2023)“…Biological tissues acquire reproducible shapes during development through dynamic cell behaviors. Most of these behaviors involve the remodeling of cell-cell…”
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Evaluation of risk factors for uric acid elevation in COVID-19 patients treated with favipiravir
Published in Diagnostic microbiology and infectious disease (01-04-2022)“…•Favipiravir dosage and age were risk factors for uricemia in COVID-19 patients•Nearly 40% of COVID-19 patients on favipiravir experience uricemia•Median onset…”
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Pharmaceutical cost comparison analysis of antimicrobial use for surgical prophylaxis on gastrectomy patients in a tertiary care hospital
Published in Chemotherapy (Basel) (01-10-2005)“…The present study investigated the clinical effects and therapeutic cost of cefazolin (CEZ) and ampicillin/sulbactam (SBT/ABPC) compared to analyze…”
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