Search Results - "NISHISHITA, Toshihide"

Inhibition of B16 melanoma growth and metastasis in C57BL mice by vaccination with a syngeneic endothelial cell line by Yoshiura, Kenta, Nishishita, Toshihide, Nakaoka, Takashi, Yamashita, Naohide, Yamashita, Naomi

“…Key role of angiogenesis in tumor growth and metastasis based on accumulating evidence and recent progress of immunotherapy have led us to investigate vaccine…”
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Calcitonin targets extracellular signal-regulated kinase signaling pathway in human cancers by Nakamura, Misa, Han, Bo, Nishishita, Toshihide, Bai, Yanhua, Kakudo, Kennichi

“…The mitogen-activated protein kinases (MAPKs) signaling pathway is a potential target in cancer therapy. Constitutive phosphorylated extracellular…”
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Carbonic Anhydrase II Is a Tumor Vessel Endothelium–Associated Antigen Targeted by Dendritic Cell Therapy by YOSHIURA, Kenta, NAKAOKA, Takashi, IMAJOH-OHMI, Shinobu, OYAIZU, Naoki, YAMASHITA, Naohide, NISHISHITA, Toshihide, SATO, Katsuaki, YAMAMOTO, Akifumi, SHIMADA, Shinji, SAIDA, Toshiaki, KAWAKAMI, Yutaka, TAKAHASHI, Tsuneo A, FUKUDA, Hiroyuki

“…Tumor-associated antigens are promising candidates as target molecules for immunotherapy and a wide variety of tumor-associated antigens have been discovered…”
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Results of a phase I clinical study using dendritic cell vaccinations for thyroid cancer by Kuwabara, Koichiro, Nishishita, Toshihide, Morishita, Mariko, Oyaizu, Naoki, Yamashita, Shunichi, Kanematsu, Takashi, Obara, Takao, Mimura, Yoshikazu, Inoue, Yusuke, Kaminishi, Michio, Kaga, Kimitaka, Amino, Nobuyuki, Kitaoka, Masafumi, Ito, Koichi, Miyauchi, Akira, Noguchi, Shiro, Uchimaru, Kaoru, Akagawa, Eiji, Watanabe, Nobukazu, Takahashi, Tsuneo A, Sato, Kaori, Inazawa, Takeshi, Nakaoka, Takashi, Yamashita, Naohide

“…We assessed the feasibility and efficacy of dendritic cell (DC) therapy for advanced thyroid papillary and follicular cancer. Six Japanese patients (2 men and…”
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A Negative Vitamin D Response DNA Element in the Human Parathyroid Hormone-related Peptide Gene Binds to Vitamin D Receptor Along with Ku Antigen to Mediate Negative Gene Regulation by Vitamin D by Nishishita, Toshihide, Okazaki, Tomoki, Ishikawa, Toshio, Igarashi, Tetsuya, Hata, Keishi, Ogata, Etsuro, Fujita, Toshiro

“…We found that the human parathyroid hormone-related peptide (hPTHrP) gene contained a DNA element (nVDREhPTHrP) homologous to a negative vitamin D response…”
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The Interaction between Ku Antigen and REF1 Protein Mediates Negative Gene Regulation by Extracellular Calcium (∗) by Chung, Ung-il, Igarashi, Tetsuya, Nishishita, Toshihide, Iwanari, Hiroko, Iwamatsu, Akihiro, Suwa, Akira, Mimori, Tsuneyo, Hata, Keishi, Ebisu, Shogo, Ogata, Etsuro, Fujita, Toshiro, Okazaki, Tomoki

“…Through the specific binding of a negative calcium-responsive element to its binding protein in response to extracellular Ca (Ca▪▪), negative…”
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Efficient Adeno-Associated Virus-Mediated Gene Expression in Human Placenta-Derived Mesenchymal Cells by Zhang, Xiaohong, Nakaoka, Takashi, Nishishita, Toshihide, Watanabe, Nobukazu, Igura, Koichi, Shinomiya, Ken-ichi, Takahashi, Tsuneo A., Yamashita, Naohide

“…Mesenchymal cells from various sources are pluripotent and are attractive sources for cell transplantation. In this study, we analyzed recombinant…”
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Inhibition of AT1 Receptor Internalization by Concanavalin A Blocks Angiotensin II-induced ERK Activation in Vascular Smooth Muscle Cells by Tang, Hua, Nishishita, Toshihide, Fitzgerald, Trinita, Landon, Erwin J., Inagami, Tadashi

“…Recent studies of β2-adrenergic receptor suggest that agonist-promoted receptor internalization may play an important role in extracellular signal-regulated…”
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A Patient with Protein-Losing Enteropathy Associated with Systemic Lupus Erythematosus by CHUNG, Ung-il, OKA, Masashi, NAKAGAWA, Yasushi, NISHISHITA, Toshihide, SEKINE, Nobuo, TANAKA, Yuji, HARADA, Shun-ichi, IGARASHI, Tetsuya, OGATA, Etsuro

“…A 46-year-old woman previously diagnosed as having systemic lupus erythematosus presented with severe hypoalbuminemia and anasarca. She was demonstrated to…”
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Differential Regulation of Cell Migration and Proliferation through Proline-Rich Tyrosine Kinase 2 in Endothelial Cells by Kuwabara, Koichiro, Nakaoka, Takashi, Sato, Kaori, Nishishita, Toshihide, Sasaki, Terukatsu, Yamashita, Naohide

“…Proline-rich tyrosine kinase 2 (Pyk2), a member of the focal adhesion kinase family, is thought to act as a key component in vasculogenesis and angiogenesis…”
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A potential pro-angiogenic cell therapy with human placenta-derived mesenchymal cells by Nishishita, Toshihide, Ouchi, Kunie, Zhang, Xiaohong, Inoue, Mariko, Inazawa, Takeshi, Yoshiura, Kenta, Kuwabara, Koichiro, Nakaoka, Takashi, Watanabe, Nobukazu, Igura, Koichi, Takahashi, Tsuneo A., Yamashita, Naohide

“…Recently several strategies to treat ischemic diseases have been proposed but the ideal way has to be determined. We explored whether human placenta-derived…”
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A redox factor protein, ref1, is involved in negative gene regulation by extracellular calcium by Okazaki, T, Chung, U, Nishishita, T, Ebisu, S, Usuda, S, Mishiro, S, Xanthoudakis, S, Igarashi, T, Ogata, E

“…A rise in extracellular calcium (Ca2+e) suppresses not only secretion of parathyroid hormone (PTH) but also expression of the PTH gene to ensure constant…”
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Inhibition of AT1 receptor internalization by concanavalin A blocks angiotensin II-induced ERK activation in vascular smooth muscle cells. Involvement of epidermal growth factor receptor proteolysis but not AT1 receptor internalization by Tang, H, Nishishita, T, Fitzgerald, T, Landon, E J, Inagami, T

“…Recent studies of beta(2)-adrenergic receptor suggest that agonist-promoted receptor internalization may play an important role in extracellular…”
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Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor α–induced angiogenesis in rheumatoid arthritis by DeBusk, Laura M., Chen, Ying, Nishishita, Toshihide, Chen, Jin, Thomas, James W., Lin, Pengnain Charles

“…Objective Rheumatoid arthritis (RA) is an inflammatory disease and an angiogenic disease. However, the molecular mechanisms promoting angiogenesis in RA are…”
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