Search Results - "NISHINAKA, Yumiko"
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Novel cystine transporter in renal proximal tubule identified as a missing partner of cystinuria-related plasma membrane protein rBAT/SLC3A1
Published in Proceedings of the National Academy of Sciences - PNAS (19-01-2016)“…Heterodimeric amino acid transporters play crucial roles in epithelial transport, as well as in cellular nutrition. Among them, the heterodimer of a membrane…”
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Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With α-Alkyl Moieties
Published in Journal of Pharmacological Sciences (2012)“…System L is a major transport system for cellular uptake of neutral amino acids. Among system L transporters, L-type amino acid transporter 1 (LAT1) is…”
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Importin α1 (Rch1) Mediates Nuclear Translocation of Thioredoxin-binding Protein-2/Vitamin D3-up-regulated Protein 1
Published in The Journal of biological chemistry (03-09-2004)“…Thioredoxin-binding protein-2 (TBP-2)/vitamin D3 up-regulated protein 1 is an endogenous molecule interacting with thioredoxin (TRX), negatively regulating TRX…”
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Circulating Thioredoxin Suppresses Lipopolysaccharide-Induced Neutrophil Chemotaxis
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2001)“…Thioredoxin (Trx), a redox enzyme with a conserved active site (Cys-32-Gly-Pro-Cys-35), is induced and secreted into circulation in response to inflammation…”
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Redox Regulation by Thioredoxin and Thioredoxin‐Binding Proteins
Published in IUBMB life (01-07-2001)“…Recent works have shown the importance of reduction/oxidation (redox) regulation in various biological phenomena. Thioredoxin is a 12‐kDa protein with…”
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Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis
Published in Laboratory investigation (01-06-2005)“…Thioredoxin is a major component of thiol-reducing system. Recently, we identified thioredoxin-binding protein-2 (TBP-2) as a negative regulator of…”
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Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice
Published in Free radical biology & medicine (15-03-2005)“…To understand the role of oxidative stress and mitochondrial defects in the development of neurodegeneration, we examined the age-related pathological changes…”
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Regulation of Human Osteoclast Differentiation by Thioredoxin Binding Protein‐2 and Redox‐Sensitive Signaling
Published in Journal of bone and mineral research (01-12-2004)“…Differential expression of TBP‐2 and Trx‐1 occurs during osteoclastogenesis. Adenoviral overexpression of TBP‐2 in osteoclast precursors inhibits Trx‐1…”
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TMX, a human transmembrane oxidoreductase of the thioredoxin family: the possible role in disulfide-linked protein folding in the endoplasmic reticulum
Published in Archives of biochemistry and biophysics (01-03-2004)“…Various proteins sharing thioredoxin (Trx)-like active site sequences (Cys–Xxx–Xxx–Cys) have been found and classified in the Trx superfamily. Among them,…”
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Structural and Immunochemical Characterization of aNeisseria gonorrhoeae Epitope Defined by a Monoclonal Antibody 2C7; the Antibody Recognizes a Conserved Epitope on Specific Lipo-oligosaccharides in Spite of the Presence of Human Carbohydrate Epitopes
Published in The Journal of biological chemistry (01-12-1999)“…Lipo-oligosaccharides (LOS) produced by Neisseria gonorrhoeae are important antigenic and immunogenic components of the outer membrane complex. Previously, we…”
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Redox-Sensing Release of Human Thioredoxin from T Lymphocytes with Negative Feedback Loops
Published in The Journal of immunology (1950) (01-01-2004)“…Thioredoxin (TRX) is released from various types of mammalian cells despite no typical secretory signal sequence. We show here that a redox-active site in TRX…”
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Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: Implications for adult T-cell leukemia leukemogenesis
Published in Cancer research (Chicago, Ill.) (15-02-2004)“…Human T-cell leukemia virus type I (HTLV-I) is the causative agent of adult T-cell leukemia (ATL). However, the low incidence of ATL among HTLV-I-infected…”
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Special issue of molecular immunology: oxidative stress signal and redox regulation
Published in Molecular immunology (2002)Get full text
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IgM Anti-Ganglioside Antibodies Induced by Melanoma Cell Vaccine Correlate with Survival of Melanoma Patients
Published in Journal of investigative dermatology (01-02-1999)“…Melanoma cells express ganglioside antigens GM3, GD3, GM2, and GD2 on their surface. This study examined whether immunization with a melanoma cell vaccine…”
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Thioredoxin cytokine action
Published in Methods in enzymology (2002)Get more information
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Importin α1 (Rch1) Mediates Nuclear Translocation of Thioredoxin-binding Protein-2/Vitamin D3-up-regulated Protein 1
Published in The Journal of biological chemistry (03-09-2004)“…Thioredoxin-binding protein-2 (TBP-2)/vitamin D 3 up-regulated protein 1 is an endogenous molecule interacting with thioredoxin (TRX), negatively regulating…”
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Importin alpha1 (Rch1) mediates nuclear translocation of thioredoxin-binding protein-2/vitamin D(3)-up-regulated protein 1
Published in The Journal of biological chemistry (03-09-2004)“…Thioredoxin-binding protein-2 (TBP-2)/vitamin D(3) up-regulated protein 1 is an endogenous molecule interacting with thioredoxin (TRX), negatively regulating…”
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Structural and immunochemical characterization of a Neisseria gonorrhoeae epitope defined by a monoclonal antibody 2C7; the antibody recognizes a conserved epitope on specific lipo-oligosaccharides in spite of the presence of human carbohydrate epitopes
Published in The Journal of biological chemistry (17-12-1999)“…Lipo-oligosaccharides (LOS) produced by Neisseria gonorrhoeae are important antigenic and immunogenic components of the outer membrane complex. Previously, we…”
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Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation
Published in Cancer research (Chicago, Ill.) (15-02-2004)“…Abstract Human T-cell leukemia virus type I (HTLV-I) is the causative agent of adult T-cell leukemia (ATL). However, the low incidence of ATL among…”
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