Search Results - "NISHIMURA, YOSHIHIRO"

Mechanism of Resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors and a Potential Treatment Strategy by Nagano, Tatsuya, Tachihara, Motoko, Nishimura, Yoshihiro

“…Treatment with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) improves the overall survival of patients with -mutated non-small-cell…”
Get full text

Bistable random laser that uses a phase transition of polyethylene glycol by Saito, Mitsunori, Nishimura, Yoshihiro

“…Polyethylene glycol (PEG) is transparent in the liquid phase and turns to a translucent solid through a phase transition at around room temperature. A PEG…”
Get full text

Focusing on Adenosine Receptors as a Potential Targeted Therapy in Human Diseases by Effendi, Wiwin Is, Nagano, Tatsuya, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Adenosine is involved in a range of physiological and pathological effects through membrane-bound receptors linked to G proteins. There are four subtypes of…”
Get full text

Baseline Tumor Size as a Predictive and Prognostic Factor of Immune Checkpoint Inhibitor Therapy for Non-small Cell Lung Cancer by Katsurada, Masahiro, Nagano, Tatsuya, Tachihara, Motoko, Kiriu, Tatsunori, Furukawa, Koichi, Koyama, Kiyoko, Otoshi, Takehiro, Sekiya, Reina, Hazama, Daisuke, Tamura, Daisuke, Nakata, Kyosuke, Katsurada, Naoko, Yamamoto, Masatsugu, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Immune checkpoint inhibitors (ICI) are a novel medication for non-small cell lung cancer (NSCLC). Recent reports indicated that baseline tumor size (BTS)…”
Get full text

A novel automatic cough frequency monitoring system combining a triaxial accelerometer and a stretchable strain sensor by Otoshi, Takehiro, Nagano, Tatsuya, Izumi, Shintaro, Hazama, Daisuke, Katsurada, Naoko, Yamamoto, Masatsugu, Tachihara, Motoko, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Objective evaluations of cough frequency are considered important for assessing the clinical state of patients with respiratory diseases. However, cough…”
Get full text

Novel Multitarget Therapies for Lung Cancer and Respiratory Disease by Yumura, Masako, Nagano, Tatsuya, Nishimura, Yoshihiro

“…In recent years, multitarget drugs for neurological diseases such as Alzheimer's disease have been developed and well researched. Many studies have revealed…”
Get full text

The time-series behavior of neutrophil-to-lymphocyte ratio is useful as a predictive marker in non-small cell lung cancer by Kiriu, Tatsunori, Yamamoto, Masatsugu, Nagano, Tatsuya, Hazama, Daisuke, Sekiya, Reina, Katsurada, Masahiro, Tamura, Daisuke, Tachihara, Motoko, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Nivolumab improves the survival of advanced non-small cell lung cancer (NSCLC), but a significant number of patients still fail to benefit from this treatment…”
Get full text

How should we manage non-small-cell lung cancer “not-otherwise-specified”? by Kim, Young Hak, Nishimura, Yoshihiro, Funada, Yasuhiro

Get full text

Operando Optical Analysis of LiFePO4 Composite Electrodes by Arai, Hajime, Yaguchi, Atsuko, Nishimura, Yoshihiro, Akimoto, Yuya, Ikezawa, Atsunori

“…Elucidating reaction inhomogeneity of composite electrodes is key to improve the performances of batteries such as rate capability and durability. Because the…”
Get full text

Hypersensitivity Pneumonitis Caused by Exposure to a Gray Parrot (Psittacus erithacus) by Enomoto, Takanori, Sekiya, Reina, Sugimoto, Hiroshi, Terashita, Tomomi, Yoshioka, Junya, Nagano, Tatsuya, Nishimura, Yoshihiro, Yano, Erika, Moriyama, Tatsuya, Nakata, Kyosuke

“…A 73-year-old woman complaining of cough and dyspnea was admitted to our hospital. High-resolution computed tomography chest revealed patchy ground-glass…”
Get full text

Multi-Institutional Prospective Cohort Study of Patients With Pulmonary Hypertension Associated With Respiratory Diseases by Tanabe, Nobuhiro, Kumamaru, Hiraku, Tamura, Yuichi, Taniguchi, Hiroyuki, Emoto, Noriaki, Yamada, Yoshihito, Nishiyama, Osamu, Tsujino, Ichizo, Kuraishi, Hiroshi, Nishimura, Yoshihiro, Kimura, Hiroshi, Inoue, Yoshikazu, Morio, Yoshiteru, Nakatsumi, Yasuto, Satoh, Toru, Hanaoka, Masayuki, Kusaka, Kei, Sumitani, Mitsuhiro, Handa, Tomohiro, Sakao, Seiicihiro, Kimura, Tomoki, Kondoh, Yasuhiro, Nakayama, Kazuhiko, Tanaka, Kensuke, Ohira, Hiroshi, Nishimura, Masaharu, Miyata, Hiroaki, Tatsumi, Koichiro, Group, for the JRPHS

“…Background:There is limited evidence for pulmonary arterial hypertension (PAH)-targeted therapy in patients with pulmonary hypertension associated with…”
Get full text

Interaction between Immunotherapy and Antiangiogenic Therapy for Cancer by Furukawa, Koichi, Nagano, Tatsuya, Tachihara, Motoko, Yamamoto, Masatsugu, Nishimura, Yoshihiro

“…Although immunotherapy has led to durable responses in diverse cancers, unfortunately, there has been limited efficacy and clinical response rates due to…”
Get full text

Glucose metabolism‐targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor‐induced drug‐tolerant persisters by Kunimasa, Kei, Nagano, Tatsuya, Shimono, Yohei, Dokuni, Ryota, Kiriu, Tatsunori, Tokunaga, Shuntaro, Tamura, Daisuke, Yamamoto, Masatsugu, Tachihara, Motoko, Kobayashi, Kazuyuki, Satouchi, Miyako, Nishimura, Yoshihiro

“…In pathway‐targeted cancer drug therapies, the relatively rapid emergence of drug‐tolerant persisters (DTPs) substantially limits the overall therapeutic…”
Get full text

Possible Biomarkers for Cancer Immunotherapy by Otoshi, Takehiro, Nagano, Tatsuya, Tachihara, Motoko, Nishimura, Yoshihiro

“…Immune checkpoint inhibitors (ICIs) have drastically changed the clinical care of cancer. Although cancer immunotherapy has shown promise in various types of…”
Get full text

Microbiome as a Target for Cancer Therapy by Suraya, Ratoe, Nagano, Tatsuya, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Recently, the microbiome has been gaining traction as a major player regulating various functions that correlate with many pathological conditions, including…”
Get full text

Diligent Medical Activities of a Publicly Designated Medical Institution for Infectious Diseases Pave the Way for Overcoming COVID-19: A Positive Message to People Working at the Cutting Edge by Nagano, Tatsuya, Arii, Jun, Nishimura, Mitsuhiro, Yoshida, Naofumi, Iida, Keiji, Nishimura, Yoshihiro, Mori, Yasuko

Get full text

Crucial Role of Extracellular Vesicles in Bronchial Asthma by Nagano, Tatsuya, Katsurada, Masahiro, Dokuni, Ryota, Hazama, Daisuke, Kiriu, Tatsunori, Umezawa, Kanoko, Kobayashi, Kazuyuki, Nishimura, Yoshihiro

“…Extracellular vesicles (EVs) are circulating vesicles secreted by various cell types. EVs are classified into three groups according to size, structural…”
Get full text

Value of diffusion-weighted MR imaging using various parameters for assessment and characterization of solitary pulmonary nodules by Koyama, Hisanobu, Ohno, Yoshiharu, Seki, Shinichiro, Nishio, Mizuho, Yoshikawa, Takeshi, Matsumoto, Sumiaki, Maniwa, Yoshimasa, Itoh, Tomoo, Nishimura, Yoshihiro, Sugimura, Kazuro

“…Highlights • Signal–intensity ratio evaluation between lesion and spinal cord is practical method. • Apparent diffusion coefficients may not contribute to the…”
Get full text

Loss of JCAD/KIAA1462 Protects the Lung from Acute and Chronic Consequences of Chronic Obstructive Pulmonary Disease by Suraya, Ratoe, Nagano, Tatsuya, Yumura, Masako, Hara, Tetsuya, Akashi, Masaya, Yamamoto, Masatsugu, Tachihara, Motoko, Nishimura, Yoshihiro, Kobayashi, Kazuyuki

“…Even with recent advances in pathobiology and treatment options, chronic obstructive pulmonary disease (COPD) remains a major contributor to morbidity and…”
Get full text

Randomized crossover trial of a demand oxygen delivery system in nocturnal hypoxemia by Yatani, Atsuhiko, Nagano, Tatsuya, Murakami, Sae, Otoshi, Takehiro, Hazama, Daisuke, Katsurada, Naoko, Yamamoto, Masatsugu, Tachihara, Motoko, Nishimura, Yoshihiro, Kobayashi, Kazuyuki

“…The newly developed portable oxygen concentrator with an auto-demand oxygen delivery system (auto-DODS) automatically switches between 3 sensitivities…”
Get full text