Search Results - "NISHIMORI, TSUKAO"

AT-1015, a Novel Serotonin (5-HT)2 Receptor Antagonist, Blocks Vascular and Platelet 5-HT2A Receptors and Prevents the Laurate-Induced Peripheral Vascular Lesion in Rats by Kihara, Hideaki, Hirose, Ken, Koganei, Hajime, Sasaki, Noriko, Yamamoto, Hiroshi, Kimura, Ayahito, Nishimori, Tsukao, Shoji, Masataka, Yoshimoto, Ryota

“…The serotonin (5-HT2A) antagonistic activities and the protective effect on laurate-induced peripheral vascular lesions of AT-1015, a novel 5-HT2 receptor…”
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Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder by Kaneko, S, Nakano, D, Ohara, M, Nishimori, T

“…Propiverine is a drug for the treatment of incontinence and pollakiuria. The effects of propiverine on isolated rat and dog urinary bladder were investigated…”
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新規頻尿・尿失禁治療剤 (±)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydtoxy-2-phenylacetate monohydrochloride monohydrate (NS-21) の活性代謝物 (RCC-36, NS-21のモノ脱エチル体) のラットにおける単回ならびに13週間反復経口投与毒性試験 by 古川, 茂典, 神山, 八郎, 菊森, 幹人, 谷口, 雄三, 西森, 司雄, 石橋, 成太良, 岩倉, 啓子, 鷲見, 信好

“…NS-21の活性代謝物であるRCC-36について, 0, 400, 600, 900, 1350および2030mg/kgの投与用量でのラット単回経口投与毒性試験ならびに0,3, 30および300mg/kgの投与用量でのラット13週間反復経口投与毒性試験および5週間回復試験を実施して,…”
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Effects of various agents on brain edema using a transcranial cold injury model in dogs by Ikeda, Hironobu, Akashi, Shinobu, Usami, Kazu, Sakonjo, Hiroshi, Ishii, Kenji, Nishimori, Tsukao

“…The brain edema is one of important factors in the acute stage of the apoplexy and elevated intracranial pressure (ICP). In this study the brain edema is…”
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Effect of electro-potential therapy apparatuses on the equivocal symptom in rats by Ishii, Kenji, Ikeda, Hironobu, Tsuchiyama, Michio, Saji, Daisuke, Tsuji, Akio, Yano, Masahiko, Kouyama, Hiroshi, Taguchi, Shigeru, Yago, Nagasumi, Nishimori, Tsukao

“…The aim of this study is to clarify the effects of electro-potential therapy apparatuses on the equivocal symptom. This study performed the influence of…”
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Effects of hyperglycemia on cerebral Ischemia in Wistar rats by Nishimura, Takaharu, Yamamuro, Masako, Yano, Masahiko, Ohhara, Masahiro, Nishimori, Tsukao

“…The effects of hyperglycemia on cerebral ischemia in Wistar rats were studied by measuring cerebral water contents (WC), tissue lactate (LA) and lipid peroxide…”
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MONTIRELIN HYDRATE (NS-3)の生殖・発生毒性試験(第4報) : ラット静脈内投与による周産期および授乳期投与試験 by 守永, 太賀彦, 藤井, 重信, 菊森, 幹人, 西森, 司雄, 渡辺, 正孝, 鷲見, 信好

“…Montirelinの0, 0.02, 1および50 mg/kgをSlc : SD系ラットの周産期および授乳期に静脈内投与し, 母動物および次世代に及ぼす影響を検討し, 以下の成績を得た。1. 母動物では, 1 mg/kg以上の投与群で摂餌量および摂水量の減少が, 50 mg/kg投与群で一過性の振戦,…”
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Effect of prazosin on analysis for the region of urethral pressure profile (UPP) in anesthetized male dogs by Ohhara, Masahiro, Sakonjo, Hiroshi, Ikeda, Hironobu, Fukuda, Yoshizo, Usami, Kazu, Nishimura, Takaharu, Nishimori, Tsukao

“…Effect of prazosin (1, 3, 10μg/kg, i.v. ) on urinary tracts was studied with the UPP in anesthetized male dogs. UPP was recorded by withdrawing the catheter at…”
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Effect of antihypertensive drugs on spinal neuronal activity in cats by Ikeda, Hironobu, Tsuchiyama, Michio, Ueda, Naoki, Morino, Kyuya, Nishimori, Tsukao

“…The relation of spinal neuronal activity (SNA) and blood pressure (BP) was investigated in cat spinal preparations, A spinal preparation (C1-C2 cut) was…”
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Effects of rearing conditions on aging characteristics and pathobiological phenotypes in SAMP10 mice by Mikito Kikumori, Shigenori Furukawa, Takayoshi Nishimura, Isami Kimura, Hironobu Ikeda, Tsukao Nishimori, Atsuyoshi Shimada, Toshio Takeda

“…The purpose of this study was to obtain background data regarding aging characteristics and pathobiological phenotypes in SAMP10//Ta(P10) and SAMR1 (R1) mice…”
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MONTIRELIN HYDRATE (NS-3)のイヌにおける26週間反復静脈内投与毒性試験ならびに9週間回復試験 by 石橋, 成太良, 西澤, 嘉人, 谷口, 雄三, 菊森, 幹人, 西森, 司雄, 岩倉, 啓子, 鷲見, 信好

“…Montirelinの0, 0.02, 0.2, 2および20 mg/kgをBeagle犬に26週間反復静脈内投与し, さらに9週間回復試験を実施して, 以下の成績を得た。1. 一般臨床検査では, 振戦, 流涎および嘔吐が0.2 mg/kg以上の投与群で, 鼻汁が全ての被験物質投与群で,…”
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Effects of cadralazine on the central nervous system by Nishimori, T, Morino, K, Tsuchiyama, M, Ikeda, H, Hasegawa, K, Higashio, T, Akita, S, Yamauchi, T, Nakao, K, Inukai, T

“…The effect of cadralazine, a new antihypertensive agent, were studied on the central nervous systems in experimental animals. Oral administration of 0.5 mg/kg…”
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MONTIRELIN HYDRATE (NS-3)のラットにおける26週間反復静脈内投与毒性試験ならびに9週間回復試験 by 古川, 茂典, 西田, 伊久男, 菊森, 幹人, 谷口, 雄三, 西森, 司雄, 石橋, 成太良, 岩倉, 啓子, 鷲見, 信好

“…Montirelinの0, 0.0004, 0.02, 1および50 mg/kg をSlc : SD系ラットに26週間反復静脈内投与し, さらに0, 1および50 mg/kg投与群については9週間回復試験を実施して, 以下の成績を得た。1. 一般臨床検査では,…”
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Effects of cadralazine on the respiration, circulation, kidney, autonomic nervous system, digestive system, blood and so on by Nishimori, T, Nishimura, T, Kobayashi, F, Nakano, D, Fukuda, Y, Sakonjyo, H, Nakanishi, J, Kimura, A, Tsuji, H, Higashio, T

“…The general pharmacological effects of cadralazine and its major metabolite ISF 2405 were studied by comparing them with those of hydralazine. Cadralazine at…”
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Distribution and excretion of 14C-labeled tazobactam/piperacillin in rats by Komuro, Masahito, Maeda, Toshimatsu, Matsushita, Hitoshi, Nozaki, Osamu, Hirao, Ryuichi, Kobayashi, Fumio, Nakano, Daizaburo, Nishimori, Tsukao

“…Tazobactam/piperacillin (TAZ/PIPC) is a 1:4 weight of combination of a new β-lactamase inhibitor, tazobactam (TAZ) and piperacillin (PIPC). We examined the…”
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Effects of somatostatin related compound SS-1 (des Ala1, Gly2[D-Trp8, D-Asu314]-somatostatin) on central and local gastric secretagogues by Nomura, Masato, Nishimura, Takaharu, Sakonjyo, Hiroshi, Nakanishi, Jun-ichi, Ikeda, Hironobu, Kanda, Shingo, Fujimoto, Rie, Nishimori, Tsukao

“…Effects of somatostatin (SS) and its related compound SS-1 on the rat gastric secretion were examined. SS-1 inhibited the acid secretion induced by bethanechol…”
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General pharmacological study on loracarbef by Saijo, Takashi, Kato, Yuzuru, Ikenaga, Tetsuji, Hattori, Osamu, Hitaka, Tamae, Hashimoto, Tamotsu, Nakanishi, Junichi, Nishimori, Tsukao, Shikuma, Hiroo, Nakazawa, Masao

“…This study was conducted to investigate the general pharmacological properties of loracarbef (LCBF), a novel orally active carbacephem. LCBF at a dose of 1000…”
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General pharmacological effects of tazobactam metabolite M-1 by Nishimori, Tsukao, Kobayashi, Fumio, Tsuchiyama, Michio, Ikeda, Hironobu, Sakonjo, Hiroshi, Nakanishi, Junichi, Fukuda, Yoshizo, Nakano, Daizaburo, Kimura, Ayato, Nishimura, Takaharu, Yamamuro, Masako, Yano, Masahiko, Kanda, Atsuhiro

“…In vivo (i. v. administration) and In vivo studies of the general pharmacological effects of the tazobactam metabolite M-1 were carried out, and the following…”
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General pharmacology of tazobactam/piperacillin (2): Effects on autonomic nervous system, isolated smooth muscles and other systems by Nishimori, Tsukao, Kobayasi, Fumio, Tsuchiyama, Michio, Ikeda, Hironobu, Sakonjo, Hiroshi, Nakanishi, Junichi, Fukuda, Yoshizo, Nakano, Daizaburo, Kimura, Ayato, Nishimura, Takaharu, Yamamuro, Masako, Kanda, Atsuhiro

“…We investigated the effects of tazobactam/piperacillin (TAZ/PIPC) given i. v. or in vitro on the autonomic nervous system, isolated smooth muscles and other…”
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General pharmacology of tazobactam/piperacillin (1): Effects on gross behavior, central nervous system, and respiratory and circulatory systems by Nishimori, Tsukao, Kobayashi, Fumio, Tsuchiyama, Michio, Ikeda, Hironobu, Sakonjo, Hiroshi, Nakanishi, Junichi, Fukuda, Yoshizo, Nakano, Daizaburo, Kimura, Ayato, Nishimura, Takaharu, Yamamuro, Masako, Ajioka, Hirofusa, Kanda, Atsuhiro

“…Tazobactam/piperacillin (TAZ/PIPC) is a 1:4 (weight) combination of tazobactam (TAZ), a new β-lactamase inhibitor, and piperacillin (PIPC). We investigated the…”
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