Search Results - "NISHIHARA, KAZUYO"

Overexpression of Trigger Factor Prevents Aggregation of Recombinant Proteins in Escherichia coli by NISHIHARA, K, KANEMORI, M, YANAGI, H, YURA, T

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Altered expression and function of P-glycoprotein in dextran sodium sulfate-induced colitis in mice by Iizasa, Hisashi, Genda, Naomi, Kitano, Tomohide, Tomita, Mikio, Nishihara, Kazuyo, Hayashi, Masahiro, Nakamura, Kayako, Kobayashi, Shizuko, Nakashima, Emi

“…P-glycoprotein (P-gp), the product of the multiple drug resistance (mdr) gene, can actively pump toxic drugs out of cells, but its pathophysiologic role is not…”
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Antiarrhythmic agents by Nishihara, Kazuyo

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Bronchodilator: theophylline by Nishihara, Kazuyo

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Improvement of productivity of active horseradish peroxidase in Escherichia coli by coexpression of Dsb proteins by Kondo, Akihiko, Kohda, Jiro, Endo, Yasunori, Shiromizu, Tokuhisa, Kurokawa, Yoichi, Nishihara, Kazuyo, Yanagi, Hideki, Yura, Takashi, Fukuda, Hideki

“…Coexpression of two classes of folding accessory proteins, molecular chaperones and foldases, can be expected to improve the productivity of soluble and active…”
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Simultaneous Assessment of the In Vivo Amount of CYP1A2 and CYP3A2 by the PKCYP-test Using Theophylline in Rats by Matsunaga, Noriko, Hayashi, Miyoko, Yamamoto, Keiko, Nishijima, Taeko, Kizu, Junko, Nishihara, Kazuyo, Takanaka, Akira, Morikawa, Akinobu, Nakashima, Emi

“…Recently, we developed a method for assessing in vivo drug metabolism capacity by pharmacokinetic estimation of the quantity of cytochrome P450 (CYP) in vivo…”
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Chaperone coexpression plasmids: differential and synergistic roles of DnaK-DnaJ-GrpE and GroEL-GroES in assisting folding of an allergen of Japanese cedar pollen, Cryj2, in Escherichia coli by Nishihara, K. (HSP Research Institute, Japan.), Kanemori, M, Kitagawa, M, Yanagi, H, Yura, T

“…Plasmids that can be used for controlled expression of the DnaK-DnaJ-GrpE and/or GroEL-GroES chaperone team were constructed in order to facilitate assessment…”
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Solvent Flush Method for Determination of Valproic Acid in Plasma by Gas Chromatography by KOHDA, YUKINAO, MATSUI, MASAMI, YAMAMOTO, KOUJIROU, NISHIHARA, KAZUYO, SAITOH, YUKIYA

“…A simple method for the determination of valproic acid (VPA) by gas chromatography, which can be applied to the direct analysis of VPA in plasma without…”
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Estimation of plasma unbound phenobarbital concentration by using mixed saliva by Nishihara, K, Uchino, K, Saitoh, Y, Honda, Y, Nakagawa, F, Tamura, Z

“…Relationships among plasma total (Ct), plasma protein unbound (Cf) and mixed salivary (Cs) concentrations of phenobarbital (PB) were studied in 29 epileptic…”
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Determination of Sultopride in Serum and Saliva by High-Performance Liquid Chromatography by NISHIHARA, KAZUYO, KOHDA, YUKINAO, TAMURA, ZENZO

“…A high-performance liquid chromatographic (HPLC) method for the determination of sultopride in serum and saliva was developed. The limit of detection of…”
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Development of an Optimum Dosage Regimen for Pentobarbital in Patients with Severe Head Injury by NISHIHARA, Kazuyo, KOHDA, Yukinao, TSUTSUMI, Haruhiko, SASAKI, Masaru, ARUGA, Tohru, TOYOOKA, Hidenori, MII, Koji

“…We attempted to determine the optimum dosage regimen for pentobarbital (PTB) in patients with head injury by using the pharmacokinetic profile obtained by…”
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Improved microdetermination for diphenylhydantoin in blood by UV spectrophotometry by Saito, Y, Nishihara, K, Nakagawa, F, Suzuki, T

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Kinetics of Diphenylhydantoin Disposition in Man by SUZUKI, TOKUJI, SAITOH, YUKIYA, NISHIHARA, KAZUYO

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Simple Method for Repetitive Blood Sampling in a Self-Controlled Design in the Rat by NISHIHARA, KAZUYO, NAKAMURA, HITOSHI, SAITOH, YUKIYA, SUZUKI, TOKUJI

“…A simple and reliable method was devised for investigating the effect of another drug on pharmacokinetic parameters of a drug in the rat. This consists of the…”
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Chaperone Coexpression Plasmids: Differential and Synergistic Roles of DnaK-DnaJ-GrpE and GroEL-GroES in Assisting Folding of an Allergen of Japanese Cedar Pollen, Cryj2, inEscherichia coli by Kazuyo Nishihara, Masaaki Kanemori, Masanari Kitagawa, Hideki Yanagi, Takashi Yura

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Synergistic roles of Hs1VU and other ATP-dependent proteases in controlling in vivo turnover of sigma32 and abnormal proteins in Escherichia coli by Kanemori, Masaaki, Nishihara, Kazuyo, Yanagi, Hideki, Yura, Takashi

“…Kanemori et al report that a multicopy plasmid carrying the hs1VU operon encoding a novel ATP-dependent protease inhibits the heat shock response induced by…”
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Improvement of productivity of active form of glutamate racemase in Escherichia coli by coexpression of folding accessory proteins by Kohda, Jiro, Endo, Yasunori, Okumura, Naotake, Kurokawa, Yoichi, Nishihara, Kazuyo, Yanagi, Hideki, Yura, Takashi, Fukuda, Hideki, Kondo, Akihiko

“…Since two classes of folding accessory proteins, molecular chaperones and foldases, prevent the misfolding of newly synthesized polypeptides in the cell, their…”
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CO-OVEREXPRESSION OF FOLDING MODULATORS IMPROVES THE SOLUBILITY OF THE RECOMBINANT GUINEA PIG LIVER TRANSGLUTAMINASE EXPRESSED IN ESCHERICHIA COLI by Ikura, Koji, Kokubu, Tsuyoshi, Natsuka, Shunji, Ichikawa, Akira, Adachi, Motoyasu, Nishihara, Kazuyo, Yanagi, Hideki, Utsumi, Shigeru

“…Transglutaminases (EC 2.3.2.13) catalyze the formation of ε -( γ -glutamyl)lysine cross-links and the substitution of primary amines for the γ -carboxamide…”
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Bioavailability of phenytoin on single and multiple oral doses of two dosage forms in normal subjects by Kohda, Y, Nishihara, K, Isozaki, S, Saitoh, Y, Nakagawa, F, Tamura, Z

“…The extent and rate of absorption of phenytoin (PHT) from tablet and powder were studied in four healthy adult volunteers. It was demonstrated by urinary and…”
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Effect of itraconazole on the pharmacokinetics of digoxin in guinea pigs by Nishihara, Kazuyo, Hibino, Junko, Kotaki, Hajime, Sawada, Yasufumi, Iga, Tatsuji

“…The effect of itraconazole (ITZ) on the pharmacokinetics of digoxin (DGX) was investigated in guinea pigs. The plasma concentrations of DGX in guinea pigs…”
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