Search Results - "NINOMIYA, YOSHIFUMI"

A new model of development of the mammalian ovary and follicles by Hummitzsch, Katja, Irving-Rodgers, Helen F, Hatzirodos, Nicholas, Bonner, Wendy, Sabatier, Laetitia, Reinhardt, Dieter P, Sado, Yoshikazu, Ninomiya, Yoshifumi, Wilhelm, Dagmar, Rodgers, Raymond J

“…Ovarian follicular granulosa cells surround and nurture oocytes, and produce sex steroid hormones. It is believed that during development the ovarian surface…”
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Brevican distinctively assembles extracellular components at the large diameter nodes of Ranvier in the CNS by Bekku, Yoko, Rauch, Uwe, Ninomiya, Yoshifumi, Oohashi, Toshitaka

“…Brevican is known to be an abundant extracellular matrix component in the adult brain and a structural constituent of perineuronal nets. We herein show that…”
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Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development by Pöschl, Ernst, Schlötzer-Schrehardt, Ursula, Brachvogel, Bent, Saito, Kenji, Ninomiya, Yoshifumi, Mayer, Ulrike

“…Basement membranes are specialized extracellular matrices consisting of tissue-specific organizations of multiple matrix molecules and serve as structural…”
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Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis by Kawabata, Tomoko, Nishida, Keiichiro, Takasugi, Koji, Ogawa, Hiroko, Sada, Kenei, Kadota, Yasutaka, Inagaki, Junko, Hirohata, Satoshi, Ninomiya, Yoshifumi, Makino, Hirofumi

“…The purpose of this study was to investigate the profile of histone deacetylase (HDAC) expression in the synovial tissue of rheumatoid arthritis (RA) compared…”
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Bral2 is indispensable for the proper localization of brevican and the structural integrity of the perineuronal net in the brainstem and cerebellum by Bekku, Yoko, Saito, Mai, Moser, Markus, Fuchigami, Maki, Maehara, Ami, Nakayama, Masaru, Kusachi, Shozo, Ninomiya, Yoshifumi, Oohashi, Toshitaka

“…Perineuronal nets (PNNs) are pericellular coats of condensed matrix that enwrap the cell bodies and dendrites of many adult central nervous system (CNS)…”
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Mechanical stretch enhances COL2A1 expression on chromatin by inducing SOX9 nuclear translocalization in inner meniscus cells by Kanazawa, Tomoko, Furumatsu, Takayuki, Hachioji, Motomi, Oohashi, Toshitaka, Ninomiya, Yoshifumi, Ozaki, Toshifumi

“…The meniscus plays an important role in controlling the biomechanics of the knee. However, the mechanical stress‐related response in meniscus cells remains…”
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Bral1: Its Role in Diffusion Barrier Formation and Conduction Velocity in the CNS by Bekku, Yoko, Vargova, Lydia, Goto, Yoshinobu, Vorisek, Ivan, Dmytrenko, Lesia, Narasaki, Masahiro, Ohtsuka, Aiji, Fassler, Reinhard, Ninomiya, Yoshifumi, Sykova, Eva, Oohashi, Toshitaka

“…At the nodes of Ranvier, excitable axon membranes are exposed directly to the extracellular fluid. Cations are accumulated and depleted in the local…”
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Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals by Fox, Michael A., Sanes, Joshua R., Borza, Dorin-Bogdan, Eswarakumar, Veraragavan P., Fässler, Reinhard, Hudson, Billy G., John, Simon W.M., Ninomiya, Yoshifumi, Pedchenko, Vadim, Pfaff, Samuel L., Rheault, Michelle N., Sado, Yoshikazu, Segal, Yoav, Werle, Michael J., Umemori, Hisashi

“…Target-derived factors organize synaptogenesis by promoting differentiation of nerve terminals at synaptic sites. Several candidate organizing molecules have…”
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ADAMTS1, ADAMTS5, ADAMTS9 and aggrecanase-generated proteoglycan fragments are induced following spinal cord injury in mouse by Demircan, Kadir, Yonezawa, Tomoko, Takigawa, Tomoyuki, Topcu, Vehap, Erdogan, Serpil, Ucar, Fatma, Armutcu, Ferah, Yigitoglu, M. Ramazan, Ninomiya, Yoshifumi, Hirohata, Satoshi

“…•Spinal cord injury (SCI) induced ADAMTS expression and proteoglycan fragmentation.•ADAMTS1, 4, 5 and 9, not -8, -15 were expressed in spinal cord tissues in…”
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Compositional Differences between Infant and Adult Human Corneal Basement Membranes by Kabosova, Andrea, Azar, Dimitri T, Bannikov, Gregory A, Campbell, Kevin P, Durbeej, Madeleine, Ghohestani, Reza F, Jones, Jonathan C. R, Kenney, M. Cristina, Koch, Manuel, Ninomiya, Yoshifumi, Patton, Bruce L, Paulsson, Mats, Sado, Yoshikazu, Sage, E. Helene, Sasaki, Takako, Sorokin, Lydia M, Steiner-Champliaud, Marie-France, Sun, Tung-Tien, SundarRaj, Nirmala, Timpl, Rupert, Virtanen, Ismo, Ljubimov, Alexander V

“…Adult human corneal epithelial basement membrane (EBM) and Descemet's membrane (DM) components exhibit heterogeneous distribution. The purpose of the study was…”
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Tumor growth inhibitory effect of ADAMTS1 is accompanied by the inhibition of tumor angiogenesis by Obika, Masanari, Ogawa, Hiroko, Takahashi, Katsuyuki, Li, Jiayi, Hatipoglu, Omer Faruk, Cilek, Mehmet Zeynel, Miyoshi, Toru, Inagaki, Junko, Ohtsuki, Takashi, Kusachi, Shozo, Ninomiya, Yoshifumi, Hirohata, Satoshi

“…Angiogenesis plays an important role in tumor progression. Several reports have demonstrated that a disintegrin and metalloproteinase with thrombospondin…”
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ADAMTS1 Is a Unique Hypoxic Early Response Gene Expressed by Endothelial Cells by Hatipoglu, Omer F., Hirohata, Satoshi, Cilek, M. Zeynel, Ogawa, Hiroko, Miyoshi, Toru, Obika, Masanari, Demircan, Kadir, Shinohata, Ryoko, Kusachi, Shozo, Ninomiya, Yoshifumi

“…ADAMTS1 (adisintegrin and metalloproteinase with thrombospondin motifs 1) is a member of the matrix metalloproteinase family. We have previously reported that…”
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Lack of Collagen XVIII Long Isoforms Affects Kidney Podocytes, whereas the Short Form Is Needed in the Proximal Tubular Basement Membrane by Kinnunen, Aino I., Sormunen, Raija, Elamaa, Harri, Seppinen, Lotta, Miller, R. Tyler, Ninomiya, Yoshifumi, Janmey, Paul A., Pihlajaniemi, Taina

“…Collagen XVIII is characterized by three variant N termini, an interrupted collagenous domain, and a C-terminal antiangiogenic domain known as endostatin. We…”
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Cardio-Ankle Vascular Index is Independently Associated with the Severity of Coronary Atherosclerosis and Left Ventricular Function in Patients with Ischemic Heart Disease by Miyoshi, Toru, Doi, Masayuki, Hirohata, Satoshi, Sakane, Kosuke, Kamikawa, Shigeshi, Kitawaki, Tomoki, Kaji, Youko, Kusano, Kengo Fukushima, Ninomiya, Yoshifumi, Kusachi, Shozo

“…Aim: The cardio-ankle vascular index (CAVI) has been proposed as a new noninvasive marker of arterial stiffness independent of blood pressure. We investigated…”
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Connective tissue growth factor induction in a pressure-overloaded heart ameliorated by the angiotensin II type 1 receptor blocker olmesartan by Iwamoto, Mutsumi, Hirohata, Satoshi, Ogawa, Hiroko, Ohtsuki, Takashi, Shinohata, Ryoko, Miyoshi, Toru, Hatipoglu, Faruk O, Kusachi, Shozo, Yamamoto, Kazuhide, Ninomiya, Yoshifumi

“…Connective tissue growth factor (CTGF) is a secreted protein that regulates fibrosis. We hypothesized that CTGF is induced in a pressure-overloaded (PO) heart…”
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Olmesartan reduces arterial stiffness and serum adipocyte fatty acid-binding protein in hypertensive patients by Miyoshi, Toru, Doi, Masayuki, Hirohata, Satoshi, Kamikawa, Shigeshi, Usui, Shinichi, Ogawa, Hiroko, Sakane, Kosuke, Izumi, Reishi, Ninomiya, Yoshifumi, Kusachi, Shozo

“…Adipocyte fatty acid binding protein (A-FABP) has been reported to be involved in insulin resistance, lipid metabolism, and atherosclerosis; however, little is…”
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Human collagen XV is a prominent histopathological component of sinusoidal capillarization in hepatocellular carcinogenesis by Kimura, Kouji, Nakayama, Masaru, Naito, Ichiro, Komiyama, Takaaki, Ichimura, Kouichi, Asano, Hiroaki, Tsukuda, Kazunori, Ohtsuka, Aiji, Oohashi, Toshitaka, Miyoshi, Shinichiro, Ninomiya, Yoshifumi

“…Background Increased expression of collagen XV has been reported in hepatocellular carcinogenesis in mice. The aim of this study was to confirm the previous…”
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Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice by Irving-Rodgers, Helen F, Hummitzsch, Katja, Murdiyarso, Lydia S, Bonner, Wendy M, Sado, Yoshikazu, Ninomiya, Yoshifumi, Couchman, John R, Sorokin, Lydia M, Rodgers, Raymond J

“…Despite the mouse being an important laboratory species, little is known about changes in its extracellular matrix (ECM) during follicle and corpora lutea…”
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Frequent deletion and down-regulation of ING4, a candidate tumor suppressor gene at 12p13, in head and neck squamous cell carcinomas by Gunduz, Mehmet, Nagatsuka, Hitoshi, Demircan, Kadir, Gunduz, Esra, Cengiz, Beyhan, Ouchida, Mamoru, Tsujigiwa, Hidetsugu, Yamachika, Eiki, Fukushima, Kunihiro, Beder, Levent, Hirohata, Satoshi, Ninomiya, Yoshifumi, Nishizaki, Kazunori, Shimizu, Kenji, Nagai, Noriyuki

“…We previously showed two members of the ING family, ING1 and ING3 as a tumor suppressor gene in head and neck cancer. Progress in human genome sequencing…”
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Light and electron microscopic detection of inflammation-targeting liposomes encapsulating high-density colloidal gold in arthritic mice by Maehara, Ami, Nishida, Keiichiro, Furutani, Masumi, Matsumoto, Emi, Ohtsuka, Aiji, Ninomiya, Yoshifumi, Oohashi, Toshitaka

“…Objective We have previously demonstrated the efficient and time-dependent transvascular localization of Sialyl Lewis X (SLX)-liposomes to inflammatory sites,…”
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