Search Results - "NING CHAN"

Substrate‐binding glycine residues are major determinants for hydrolase and ligase activity of plant legumains by Hemu, Xinya, Chan, Ning‐Yu, Liew, Heng Tai, Hu, Side, Zhang, Xiaohong, Serra, Aida, Lescar, Julien, Liu, Chuan‐Fa, Tam, James P.

“…Summary Peptide asparaginyl ligases (PALs) are useful tools for precision modifications of proteins and live‐cell surfaces by ligating peptides after Asn/Asp…”
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Three‐year outcomes of an optometrist‐led virtual clinic for new glaucoma referrals by Karthikeyan, Anuragini, Lee, Chan Ning, Myneni, Jaya, Harthan, Stephen, Bragg, Kris, Bentley, Sarah, Dubois, Vincent, Bhan, Anna

“…Introduction The purpose of this study was to describe and evaluate the outcomes of an optometrist‐led virtual glaucoma clinic (VGC). Methods New patients…”
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Nγ‐Hydroxyasparagine: A Multifunctional Unnatural Amino Acid That is a Good P1 Substrate of Asparaginyl Peptide Ligases by Xia, Yiyin, To, Janet, Chan, Ning‐Yu, Hu, Side, Liew, Heng Tai, Balamkundu, Seetharamsing, Zhang, Xiaohong, Lescar, Julien, Bhattacharjya, Surajit, Tam, James P., Liu, Chuan‐Fa

“…Peptidyl asparaginyl ligases (PALs) are powerful tools for peptide macrocyclization. Herein, we report that a derivative of Asn, namely Nγ‐hydroxyasparagine or…”
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Asparaginyl Endopeptidase-Mediated Protein C‑Terminal Hydrazinolysis for the Synthesis of Bioconjugates by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Chan, Ning-Yu, Liew, Heng Tai, Lescar, Julien, Tam, James P, Liu, Chuan-Fa

“…Asparaginyl endopeptidases (AEPs) are cysteinyl enzymes naturally catalyzing the hydrolysis and transpeptidation reactions at Asx–Xaa bonds. These reactions go…”
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The legumain McPAL1 from Momordica cochinchinensis is a highly stable Asx-specific splicing enzyme by Liew, Heng Tai, To, Janet, Zhang, Xiaohong, Hemu, Xinya, Chan, Ning-Yu, Serra, Aida, Sze, Siu Kwan, Liu, Chuan-fa, Tam, James P.

“…Legumains, also known as asparaginyl endopeptidases (AEPs), cleave peptide bonds after Asn/Asp (Asx) residues. In plants, certain legumains also have ligase…”
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Inflammatory Myofibroblastic Tumors of the Urinary Bladder: A Systematic Review by Teoh, Jeremy Yuen Chun, Chan, Ning-Hong, Cheung, Ho-Yuen, Hou, Simon See Ming, Ng, Chi-Fai

“…We systemically reviewed the literature on inflammatory myofibroblastic tumors (IMTs) of the urinary bladder and compared between anaplastic lymphoma kinase…”
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Insights from three-dimensional computational fluid dynamics modelling of a scroll vortex intake by Chan, Shu Ning

“…Scroll vortex intakes are commonly used in water supply, drainage and sewerage systems. Water flows into the intake via an eccentric approach channel, forming…”
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Chemotherapy-induced peripheral neuropathy in newly diagnosed breast cancer survivors treated with taxane: a prospective longitudinal study by Wang, Ya-Jung, Chan, Ya-Ning, Jheng, You-Wun, Wu, Chih-Jung, Lin, Ming-Wei, Tseng, Ling-Ming, Tsai, Yi-Fang, Liu, Liang-Chih

“…Purpose This study aimed to prospectively explore severity and prevalence of chemotherapy-induced peripheral neuropathy (CIPN) and examine the correlation…”
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Anti-factor Xa level monitoring of low-molecular-weight heparin for prevention of venous thromboembolism in critically ill patients (AXaLPE): protocol of a randomised, open-label controlled clinical trial by Wang, Chunmei, Ning, Ya-chan, Song, Li-po, Li, Pei-juan, Wang, Feng-hua, Ding, Meng-xi, Jiang, Li, Wang, Meiping, Pei, Qian-Qian, Hu, Shi-min, Wang, Haibo

“…IntroductionWhether and when to monitor the amount of anti-factor Xa (aFXa) activity in critically ill patients with complex diseases to prevent venous…”
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microRNA expression pattern as an ancillary prognostic signature for radiotherapy by Li, An-Lun, Chung, Tao-Sang, Chan, Yao-Ning, Chen, Chien-Lung, Lin, Shih-Chieh, Chiang, Yun-Ru, Lin, Chen-Huan, Chen, Chi-Ching, Ma, Nianhan

“…In view of the limited knowledge of plasma biomarkers relating to cancer resistance to radiotherapy, we have set up screening, training and testing stages to…”
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Use of Video Education Interventions to Increase Racial and Ethnic Diversity in Cancer Clinical Trials: A Systematic Review by Nolan, Timiya S., Bell, Ana’ M., Chan, Ya‐Ning, Leak Bryant, Ashley, Bissram, Jennifer S., Hirschey, Rachel

“…Background Less than 5% of eligible adult cancer survivors participate in cancer clinical trials. Survivors identifying as Black, Indigenous, and people of…”
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Peptide asparaginyl ligases—renegade peptide bond makers by Tam, James P., Chan, Ning-Yu, Liew, Heng Tai, Tan, Shaun J., Chen, Yu

“…Making peptide bonds is tightly controlled by genetic code and machinery which includes cofactors, ATP, and RNAs. In this regard, the stand-alone and…”
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Stereotactic radiotherapy for neovascular age-related macular degeneration (STAR): a pivotal, randomised, double-masked, sham-controlled device trial by Jackson, Timothy L, Desai, Riti, Wafa, Hatem A, Wang, Yanzhong, Peacock, Janet, Peto, Tunde, Chakravarthy, Usha, Dakin, Helen, Wordsworth, Sarah, Lewis, Cornelius, Clinch, Patricia, Ramazzotto, Lisa, Neffendorf, James E, Lee, Chan Ning, O'Sullivan, Joe M, Reeves, Barnaby C, Abugreen, Salwa, Bindra, Mandeep, Burton, Ben, Dias, Indra, Dinah, Christiana, Gandhewar, Ravikiran, Georgas, Athanasios, Goverdhan, Srinivas, Gulrez, Ansari, Haynes, Richard, Hughes, Edward, Jackson (Chief Investigator), Timothy, Jafree, Afsar, Joseph, Sobha, Kashab, Tarek, Membrey, Luke, Menon, Geeta, Misra, Aseema, Narendran, Niro, Newman, Douglas, Patel, Jignesh, Patra, Sudeshna, Petrarca, Robert, Priya, Prakash, Rashi, Arora, Salom, Ramiro, Shah, Paritosh, Shahrnaz, Izadi, Sheen, George, Shiew, Marianne, Tesha, Paul, Vrizidou, Eleni

“…Neovascular age-related macular degeneration (nAMD) is a leading cause of blindness. The first-line therapy is anti-vascular endothelial growth factor…”
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Chemotherapy-Induced Peripheral Neurotoxicity as A Risk Factor for Poor Sleep Quality in Breast Cancer Survivors Treated with Docetaxel by Chan, Ya-Ning, Jheng, You-Wun, Wang, Ya-Jung

“…Objective: The purpose of this study was to explore sleep quality and to determine whether chemotherapy-induced peripheral neurotoxicity is a risk factor for…”
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Patient‐reported motor chemotherapy‐induced peripheral neuropathy impacts function in advanced colorectal cancer survivors receiving chemotherapy: A cross‐sectional study by Hsieh, Chia‐Fen, Chan, Ya‐Ning, Wu, Chih‐Jung, Yen, Li‐Yu, Chang, Yu‐Chi, Wang, Ya‐Jung

“…Aims Chemotherapy‐induced peripheral neuropathy limits cancer survivors' compliance with chemotherapy and impaired function. This study aimed to examine…”
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Vitrectomy, subretinal Tissue plasminogen activator and Intravitreal Gas for submacular haemorrhage secondary to Exudative Age-Related macular degeneration (TIGER): study protocol for a phase 3, pan-European, two-group, non-commercial, active-control, observer-masked, superiority, randomised controlled surgical trial by Jackson, Timothy L, Bunce, Catey, Desai, Riti, Hillenkamp, Jost, Lee, Chan Ning, Lois, Noemi, Peto, Tunde, Reeves, Barnaby C, Steel, David H, Edwards, Rhiannon T, van Meurs, Jan C, Wafa, Hatem, Wang, Yanzhong

“…Neovascular (wet) age-related macular degeneration (AMD) can be associated with large submacular haemorrhage (SMH). The natural history of SMH is very poor,…”
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Rogue Wave Modes for the Long Wave--Short Wave Resonance Model by Chow, Kwok Wing, Chan, Hiu Ning, Kedziora, David Jacob, Grimshaw, Roger Hamilton James

“…The long wave--short wave resonance model arises physically when the phase velocity of a long wave matches the group velocity of a short wave. It is a system…”
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Comparative outcomes of selective laser trabeculoplasty delivered by optometrists compared with ophthalmologists: a UK-based multicentre observational study by Lee, Chan Ning, Delaney, Alexander, Richardson, Jay A L, Freeman, Graham, Gunn, Patrick J G, Harthan, Stephen, Dubois, Vincent, Yau, Kenneth, Hemmerdinger, Christopher, Harper, Robert, Vallabh, Neeru A

“…BackgroundSelective laser trabeculoplasty (SLT), a National Institute for Care and Health Excellence recommended first-line treatment for open-angle glaucoma…”
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Comparison of a Smartphone Otoscope and Conventional Otoscope in the Diagnosis and Management of Acute Otitis Media by Chan, K. Ning, Silverstein, Anna, Bryan, Leah N., McCracken, Courtney E., Little, Wendalyn K., Shane, Andi L.

“…Acute otitis media (AOM) is a leading cause of health encounters and antimicrobial prescriptions in children worldwide. We assessed (1) the rates of…”
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Effects of mussels on nutrient cycling and bioseston in two contrasting tropical freshwater habitats by Zieritz, Alexandra, Mahadzir, Farah Najwa, Chan, Wei Ning, McGowan, Suzanne

“…Freshwater mussels (Unionida) can strongly affect nutrient cycling in temperate ecosystems but data from the tropics is lacking. We quantified the effects of…”
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