Search Results - "NIMGAONKAR, V"

The complement system: a gateway to gene–environment interactions in schizophrenia pathogenesis by Nimgaonkar, V L, Prasad, K M, Chowdari, K V, Severance, E G, Yolken, R H

“…The pathogenesis of schizophrenia is considered to be multi-factorial, with likely gene–environment interactions (GEI). Genetic and environmental risk factors…”
Get full text

Whole-genome association study of bipolar disorder by Sklar, P, Smoller, J W, Fan, J, Ferreira, M A R, Perlis, R H, Chambert, K, Nimgaonkar, V L, McQueen, M B, Faraone, S V, Kirby, A, de Bakker, P I W, Ogdie, M N, Thase, M E, Sachs, G S, Todd-Brown, K, Gabriel, S B, Sougnez, C, Gates, C, Blumenstiel, B, Defelice, M, Ardlie, K G, Franklin, J, Muir, W J, McGhee, K A, MacIntyre, D J, McLean, A, VanBeck, M, McQuillin, A, Bass, N J, Robinson, M, Lawrence, J, Anjorin, A, Curtis, D, Scolnick, E M, Daly, M J, Blackwood, D H, Gurling, H M, Purcell, S M

“…We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1 disorder, 2008 controls drawn from the Systematic Treatment Enhancement…”
Get full text

Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder by Williams, H J, Norton, N, Dwyer, S, Moskvina, V, Nikolov, I, Carroll, L, Georgieva, L, Williams, N M, Morris, D W, Quinn, E M, Giegling, I, Ikeda, M, Wood, J, Lencz, T, Hultman, C, Lichtenstein, P, Thiselton, D, Maher, B S, Malhotra, A K, Riley, B, Kendler, K S, Gill, M, Sullivan, P, Sklar, P, Purcell, S, Nimgaonkar, V L, Kirov, G, Holmans, P, Corvin, A, Rujescu, D, Craddock, N, Owen, M J, O'Donovan, M C

“…A recent genome-wide association study (GWAS) reported evidence for association between rs1344706 within ZNF804A (encoding zinc-finger protein 804A) and…”
Get full text

Personality and bipolar disorder: dissecting state and trait associations between mood and personality by Barnett, J H, Huang, J, Perlis, R H, Young, M M, Rosenbaum, J F, Nierenberg, A A, Sachs, G, Nimgaonkar, V L, Miklowitz, D J, Smoller, J W

“…Some personality characteristics have previously been associated with an increased risk for psychiatric disorder. Longitudinal studies are required in order to…”
Get more information

Elevated serum measures of lipid peroxidation and abnormal prefrontal white matter in euthymic bipolar adults: toward peripheral biomarkers of bipolar disorder by Versace, A, Andreazza, A C, Young, L T, Fournier, J C, Almeida, J R C, Stiffler, R S, Lockovich, J C, Aslam, H A, Pollock, M H, Park, H, Nimgaonkar, V L, Kupfer, D J, Phillips, M L

“…Diffusion tensor imaging (DTI) studies consistently reported abnormalities in fractional anisotropy (FA) and radial diffusivity (RD), measures of the integrity…”
Get full text

Heritable anisotropy associated with cognitive impairments among patients with schizophrenia and their non-psychotic relatives in multiplex families by Prasad, K M, Gertler, J, Tollefson, S, Wood, J A, Roalf, D, Gur, R C, Gur, R E, Almasy, L, Pogue-Geile, M F, Nimgaonkar, V L

“…To test the functional implications of impaired white matter (WM) connectivity among patients with schizophrenia and their relatives, we examined the…”
Get more information

All the world’s a (clinical) stage: rethinking bipolar disorder from a longitudinal perspective by Frank, E, Nimgaonkar, V L, Phillips, M L, Kupfer, D J

“…Psychiatric disorders have traditionally been classified using a static, categorical approach. However, this approach falls short in facilitating understanding…”
Get full text

Possible role of rare variants in Trace amine associated receptor 1 in schizophrenia by John, Jibin, Kukshal, Prachi, Bhatia, Triptish, Chowdari, K.V, Nimgaonkar, V.L, Deshpande, S.N, Thelma, B.K

“…Abstract Schizophrenia (SZ) is a chronic mental illness with behavioral abnormalities. Recent common variant based genome wide association studies and rare…”
Get full text

Multiple rare inherited variants in a four generation schizophrenia family offer leads for complex mode of disease inheritance by John, Jibin, Bhattacharyya, Upasana, Yadav, Navneesh, Kukshal, Prachi, Bhatia, Triptish, Nimgaonkar, V.L., Deshpande, Smita N., Thelma, B.K.

“…Schizophrenia is a clinically and genetically heterogeneous neuropsychiatric disorder, with a polygenic basis but identification of the specific determinants…”
Get full text

Rare variants in Protein tyrosine phosphatase, receptor type A (PTPRA) in schizophrenia: Evidence from a family based study by John, Jibin, Kukshal, Prachi, Sharma, Aditya, Bhatia, Triptish, Nimgaonkar, V.L., Deshpande, S.N., Thelma, B.K.

“…The contribution of both common and rare risk variants to the genetic architecture of schizophrenia (SZ) has been documented in genome-wide association…”
Get full text

Rare variant based evidence for oligogenic contribution of neurodevelopmental pathway genes to schizophrenia by John, Jibin, Kukshal, Prachi, Bhatia, Triptish, Nimgaonkar, V.L., Deshpande, S.N., Thelma, B.K.

Get full text

Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia by Mansour, H. A., Wood, J., Logue, T., Chowdari, K. V., Dayal, M., Kupfer, D. J., Monk, T. H., Devlin, B., Nimgaonkar, V. L.

“…We hypothesize that circadian dysfunction could underlie, at least partially, the liability for bipolar 1 disorder (BD1). Our hypothesis motivated tests for…”
Get full text

Meta-analysis of 32 genome-wide linkage studies of schizophrenia by Ng, M Y M, Levinson, D F, Faraone, S V, Suarez, B K, DeLisi, L E, Arinami, T, Riley, B, Paunio, T, Pulver, A E, Irmansyah, Holmans, P A, Escamilla, M, Wildenauer, D B, Williams, N M, Laurent, C, Mowry, B J, Brzustowicz, L M, Maziade, M, Sklar, P, Garver, D L, Abecasis, G R, Lerer, B, Fallin, M D, Gurling, H M D, Gejman, P V, Lindholm, E, Moises, H W, Byerley, W, Wijsman, E M, Forabosco, P, Tsuang, M T, Hwu, H-G, Okazaki, Y, Kendler, K S, Wormley, B, Fanous, A, Walsh, D, O'Neill, F A, Peltonen, L, Nestadt, G, Lasseter, V K, Liang, K Y, Papadimitriou, G M, Dikeos, D G, Schwab, S G, Owen, M J, O'Donovan, M C, Norton, N, Hare, E, Raventos, H, Nicolini, H, Albus, M, Maier, W, Nimgaonkar, V L, Terenius, L, Mallet, J, Jay, M, Godard, S, Nertney, D, Alexander, M, Crowe, R R, Silverman, J M, Bassett, A S, Roy, M-A, Mérette, C, Pato, C N, Pato, M T, Roos, J Louw, Kohn, Y, Amann-Zalcenstein, D, Kalsi, G, McQuillin, A, Curtis, D, Brynjolfson, J, Sigmundsson, T, Petursson, H, Sanders, A R, Duan, J, Jazin, E, Myles-Worsley, M, Karayiorgou, M, Lewis, C M

“…A genome scan meta-a nalysis (GSMA) was carried out on 32 independent genome-wide linkage scan analyses that included 3255 pedigrees with 7413 genotyped cases…”
Get full text

Persistent infection with neurotropic herpes viruses and cognitive impairment by Watson, A M M, Prasad, K M, Klei, L, Wood, J A, Yolken, R H, Gur, R C, Bradford, L D, Calkins, M E, Richard, J, Edwards, N, Savage, R M, Allen, T B, Kwentus, J, McEvoy, J P, Santos, A B, Wiener, H W, Go, R C P, Perry, R T, Nasrallah, H A, Gur, R E, Devlin, B, Nimgaonkar, V L

“…Herpes virus infections can cause cognitive impairment during and after acute encephalitis. Although chronic, latent/persistent infection is considered to be…”
Get more information

Antipsychotic pharmacogenomics in first episode psychosis: a role for glutamate genes by Stevenson, J M, Reilly, J L, Harris, M S H, Patel, S R, Weiden, P J, Prasad, K M, Badner, J A, Nimgaonkar, V L, Keshavan, M S, Sweeney, J A, Bishop, J R

“…Genetic factors may underlie beneficial and adverse responses to antipsychotic treatment. These relationships may be easier to identify among patients early in…”
Get full text

Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients by PRASAD, K. M. R, CHOWDARI, K. V, NIMGAONKAR, V. L, TALKOWSKI, M. E, LEWIS, D. A, KESHAVAN, M. S

“…Polymorphisms of the gene encoding the regulator of G-protein signaling subtype 4 (RGS4) may confer risk for schizophrenia.(1) DNA microarray studies of…”
Get full text

Imprinting in the schizophrenia candidate gene GABRB2 encoding GABA(A) receptor β(2) subunit by Pun, F W, Zhao, C, Lo, W-S, Ng, S-K, Tsang, S-Y, Nimgaonkar, V, Chung, W S, Ungvari, G S, Xue, H

“…Schizophrenia is a complex genetic disorder, the inheritance pattern of which is likely complicated by epigenetic factors yet to be elucidated. In this study,…”
Get full text

Correlates of hallucinations in schizophrenia: A cross‐cultural evaluation by Thomas, P, Mathur, P, Gottesman, I.I, Nagpal, R, Nimgaonkar, V.L, Deshpande, S.N

“…Abstract Introduction Demographic, clinical and familial factors may plausibly influence the manifestation of hallucinations. It is unclear if the pattern of…”
Get full text

Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia by PRASAD, K. M. R, SHIRTS, B. H, YOLKEN, R. H, KESHAVAN, M. S, NIMGAONKAR, V. L

“…Infectious agents have been proposed as one of the risk factors for schizophrenia. However, the data on the association of infectious agents with in vivo brain…”
Get full text

Combined Analysis from Eleven Linkage Studies of Bipolar Disorder Provides Strong Evidence of Susceptibility Loci on Chromosomes 6q and 8q by McQueen, Matthew B., Devlin, B., Faraone, Stephen V., Nimgaonkar, Vishwajit L., Sklar, Pamela, Smoller, Jordan W., Abou Jamra, Rami, Albus, Margot, Bacanu, Silviu-Alin, Baron, Miron, Barrett, Thomas B., Berrettini, Wade, Blacker, Deborah, Byerley, William, Cichon, Sven, Coryell, Willam, Craddock, Nick, Daly, Mark J., DePaulo, J. Raymond, Edenberg, Howard J., Foroud, Tatiana, Gill, Michael, Gilliam, T. Conrad, Hamshere, Marian, Jones, Ian, Jones, Lisa, Juo, Suh-Hang, Kelsoe, John R., Lambert, David, Lange, Christoph, Lerer, Bernard, Liu, Jianjun, Maier, Wolfgang, MacKinnon, James D., McInnis, Melvin G., McMahon, Francis J., Murphy, Dennis L., Nöthen, Markus M., Nurnberger, John I., Pato, Carlos N., Pato, Michele T., Potash, James B., Propping, Peter, Pulver, Ann E., Rice, John P., Rietschel, Marcella, Scheftner, William, Schumacher, Johannes, Segurado, Ricardo, Van Steen, Kristel, Xie, Weiting, Zandi, Peter P., Laird, Nan M.

“…Several independent studies and meta-analyses aimed at identifying genomic regions linked to bipolar disorder (BP) have failed to find clear and consistent…”
Get full text