Search Results - "NILSSON, A"
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The small leucine‐rich repeat proteoglycans in tissue repair and atherosclerosis
Published in Journal of internal medicine (01-11-2015)“…Proteoglycans consist of a protein core with one or more covalently attached glycosaminoglycan (GAG) side chains and have multiple roles in the initiation and…”
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2
RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics
Published in Cancer cell (09-11-2015)“…Tumor-educated blood platelets (TEPs) are implicated as central players in the systemic and local responses to tumor growth, thereby altering their RNA…”
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3
DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity
Published in Immunity (Cambridge, Mass.) (17-02-2015)“…Dysfunction in Ataxia-telangiectasia mutated (ATM), a central component of the DNA repair machinery, results in Ataxia Telangiectasia (AT), a cancer-prone…”
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4
Multi-locus Analyses Reveal Four Giraffe Species Instead of One
Published in Current biology (26-09-2016)“…Traditionally, one giraffe species and up to eleven subspecies have been recognized [1]; however, nine subspecies are commonly accepted [2]. Even after a…”
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Determinants of serum half-lives for linear and branched perfluoroalkyl substances after long-term high exposure—A study in Ronneby, Sweden
Published in Environment international (01-05-2022)“…[Display omitted] •This study provides refined estimates of the half-life of eight PFAS, especially including the branched PFOS-isomers.•The determinants…”
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6
Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types
Published in Nature genetics (01-12-2014)“…Erik Larsson and colleagues present an analysis pipeline for identifying likely transcription-altering noncoding somatic mutations in cancer using publicly…”
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Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial
Published in Journal of internal medicine (01-09-2018)“…Background The importance of the gut microbiome for bone metabolism in mice has recently been demonstrated, but no studies are available in humans…”
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8
Estimating mortality of small passerine birds colliding with wind turbines
Published in Scientific reports (04-12-2023)“…As demand for renewable energy is rising, wind power development is rapidly growing worldwide. In its wake, conflicts arise over land use changes converting…”
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9
Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets
Published in PLoS genetics (01-11-2014)“…Genetic and epigenetic mechanisms may interact and together affect biological processes and disease development. However, most previous studies have…”
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10
Antioxidants accelerate lung cancer progression in mice
Published in Science translational medicine (29-01-2014)“…Antioxidants are widely used to protect cells from damage induced by reactive oxygen species (ROS). The concept that antioxidants can help fight cancer is…”
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Associations of Maternal Diabetes and Body Mass Index With Offspring Birth Weight and Prematurity
Published in JAMA pediatrics (01-04-2019)“…Maternal obesity, pregestational type 1 diabetes, and gestational diabetes have been reported to increase the risks for large birth weight and preterm birth in…”
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The evolutionary history of bears is characterized by gene flow across species
Published in Scientific reports (19-04-2017)“…Bears are iconic mammals with a complex evolutionary history. Natural bear hybrids and studies of few nuclear genes indicate that gene flow among bears may be…”
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13
Tests of standard cosmology in Hořava gravity, Bayesian evidence for a closed universe, and the Hubble tension
Published in The European physical journal. C, Particles and fields (01-10-2022)“…We consider some background tests of standard cosmology in the context of Hořava gravity with different scaling dimensions for space and time, which has been…”
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14
Improved Cortisol Exposure-Time Profile and Outcome in Patients with Adrenal Insufficiency: A Prospective Randomized Trial of a Novel Hydrocortisone Dual-Release Formulation
Published in The journal of clinical endocrinology and metabolism (01-02-2012)“…Context: Patients with treated adrenal insufficiency (AI) have increased morbidity and mortality rate. Our goal was to improve outcome by developing a…”
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15
RNAi delivery by exosome-mimetic nanovesicles – Implications for targeting c-Myc in cancer
Published in Biomaterials (01-09-2016)“…Abstract To develop RNA-based therapeutics, it is crucial to create delivery vectors that transport the RNA molecule into the cell cytoplasm. Naturally…”
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Mast cell-dependent IL-33/ST2 signaling is protective against the development of airway hyperresponsiveness in a house dust mite mouse model of asthma
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2018)“…Interleukin-33 (IL-33) and its receptor ST2 have been influentially associated with the pathophysiology of asthma. Due to the divergent roles of IL-33 in…”
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Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes
Published in Immunity (Cambridge, Mass.) (20-10-2015)“…Pattern-recognition receptors (PRRs) including Toll-like receptors, RIG-I-like receptors, and cytoplasmic DNA receptors are essential for protection against…”
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Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
Published in Nature communications (27-09-2017)“…Immune checkpoint inhibitors and adoptive cell transfer (ACT) of autologous tumor-infiltrating T cells have shown durable responses in patients with melanoma…”
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Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma
Published in Scientific reports (26-06-2017)“…Interleukin 33 (IL-33) represents a potential link between the airway epithelium and induction of Th2-type inflammatory responses associated with the…”
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DECLARE‐TIMI 58: Participants’ baseline characteristics
Published in Diabetes, obesity & metabolism (01-05-2018)“…Aim To describe the baseline characteristics of participants randomized in the Dapagliflozin Effect on CardiovascuLAR Events (DECLARE‐TIMI 58) trial, the…”
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