Search Results - "NILSEN, JON"

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease by Yao, Jia, Irwin, Ronald W, Zhao, Liqin, Nilsen, Jon, Hamilton, Ryan T, Brinton, Roberta Diaz

“…Mitochondrial dysfunction has been proposed to play a pivotal role in neurodegenerative diseases, including Alzheimer's disease (AD). To address whether…”
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Impact of Progestins on Estrogen-Induced Neuroprotection: Synergy by Progesterone and 19-Norprogesterone and Antagonism by Medroxyprogesterone Acetate by Nilsen, Jon, Brinton, Roberta Diaz

“…Estrogen replacement therapy is associated with improvement of cognitive deficits and reduced incidence of Alzheimer’s disease. To compare the impact of…”
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Progesterone and Estrogen Regulate Oxidative Metabolism in Brain Mitochondria by Irwin, Ronald W, Yao, Jia, Hamilton, Ryan T, Cadenas, Enrique, Brinton, Roberta Diaz, Nilsen, Jon

“…The ovarian hormones progesterone and estrogen have well-established neurotrophic and neuroprotective effects supporting both reproductive function and…”
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Divergent Impact of Progesterone and Medroxyprogesterone Acetate (Provera) on Nuclear Mitogen-Activated Protein Kinase Signaling by Nilsen, Jon, Brinton, Roberta Diaz

“…The impact of progestins on estrogen-inducible mechanisms of neuroprotection was investigated. Previously, we showed that estrogen and progesterone are…”
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Efficacy and safety of the glycine transporter type-1 inhibitor AMG 747 for the treatment of negative symptoms associated with schizophrenia by Dunayevich, Eduardo, MD, Buchanan, Robert W, MD, Chen, Chao-Yin, PhD, Yang, Jun, PhD, Nilsen, Jon, PhD, Dietrich, Julie M, MS, Sun, Hong, MD, PhD, Marder, Stephen, MD

“…Abstract Objective To determine the safety and efficacy of AMG 747, an oral inhibitor of glycine transporter type-1 (GlyT1), as an add-on to antipsychotic…”
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Progesterone Increases Rat Neural Progenitor Cell Cycle Gene Expression and Proliferation Via Extracellularly Regulated Kinase and Progesterone Receptor Membrane Components 1 and 2 by Liu, Lifei, Wang, Junming, Zhao, Liqin, Nilsen, Jon, McClure, Kelsey, Wong, Karren, Brinton, Roberta Diaz

“…Progesterone receptor (PR) expression and regulation of neural progenitor cell (NPC) proliferation was investigated using NPC derived from adult rat brain…”
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Mechanism of Estrogen-Mediated Neuroprotection: Regulation of Mitochondrial Calcium and Bcl-2 Expression by Nilsen, Jon, Brinton, Roberta Diaz

“…Estrogens are neuroprotective against glutamate excitotoxicity caused by an excessive rise in intracellular calcium ([ Ca2+]i). In this study, we demonstrate…”
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Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function by Nilsen, Jon, Chen, Shuhua, Irwin, Ronald W, Iwamoto, Sean, Brinton, Roberta Diaz

“…Neurodegeneration in Alzheimer's disease is associated with increased apoptosis and parallels increased levels of amyloid beta, which can induce neuronal…”
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LDL protein nitration: Implication for LDL protein unfolding by Hamilton, Ryan T., Asatryan, Liana, Nilsen, Jon T., Isas, Jose M., Gallaher, Timothy K., Sawamura, Tatsuya, Hsiai, Tzung K.

“…Oxidatively- or enzymatically-modified low-density lipoprotein (LDL) is intimately involved in the initiation and progression of atherosclerosis. The in vivo…”
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Estradiol Prevents Neural Tau Hyperphosphorylation Characteristic of Alzheimer's Disease by ALVAREZ-DE-LA-ROSA, MARGARITA, SILVA, IVALDO, NILSEN, JON, PÉREZ, M. M., GARCÍA-SEGURA, LUIS MIGUEL, ÁVILA, JESÚS, NAFTOLIN, FREDERICK

“…: Alzheimer's disease (AD) is three times more prevalent in women than men, and epidemiological studies have shown that estrogen replacement in aging women…”
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Dual action of estrogen on glutamate-induced calcium signaling: mechanisms requiring interaction between estrogen receptors and src/mitogen activated protein kinase pathway by Nilsen, Jon, Chen, Shuhua, Brinton, Roberta Diaz

“…Conjugated equine estrogens (CEE) is the most widely prescribed pharmaceutical estrogen replacement therapy (ERT) for postmenopausal women in the United States…”
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Changes in cerebral cortex size are governed by fibroblast growth factor during embryogenesis by Vaccarino, Flora M, Schwartz, Michael L, Raballo, Rossana, Nilsen, Jon, Rhee, Julianne, Zhou, Ming, Doetschman, Thomas, Coffin, J. Douglas, Wyland, Jason J, Hung, Yu-Ting E

“…We show that fibroblast growth factor 2 (FGF2) and FGF receptors are transiently expressed by cells of the pseudostratified ventricular epithelium (PVE) during…”
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FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: Evidence for the existence of an immunological brain barrier by Bechmann, Ingo, Mor, Gil, Nilsen, Jon, Eliza, Mariel, Nitsch, Robert, Naftolin, Frederick

“…Despite the mechanical blood‐brain barrier, activated T‐cells can cross brain vessels. Thus, the CNS is routinely surveyed by immune competent cells; yet the…”
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Gravimetric Method for in Vitro Calibration of Skin Hydration Measurements by Martinsen, Ørjan G., Grimnes, Sverre, Nilsen, Jon K., Tronstad, Christian, Jang, Wooyoung, Kim, Hongsig, Shin, Kunsoo, Naderi, Majid, Thielmann, Frank

“…A novel method for in vitro calibration of skin hydration measurements is presented. The method combines gravimetric and electrical measurements and reveals an…”
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Learning how to lead police investigations by Nilsen, Jon-Andre, Aaserud, Terje, Filstad, Cathrine

“…The aim of this article was to investigate how police investigation leaders learn leadership and whether the facilitation of learning activities and learning…”
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Estradiol and neurodegenerative oxidative stress by Nilsen, Jon

“…Abstract Estradiol is a potent preventative against neurodegenerative disease, in part, by activating antioxidant defense systems scavenging reactive oxygen…”
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Erenumab in chronic migraine with medication overuse: Subgroup analysis of a randomized trial by Tepper, Stewart J, Diener, Hans-Christoph, Ashina, Messoud, Brandes, Jan Lewis, Friedman, Deborah I, Reuter, Uwe, Cheng, Sunfa, Nilsen, Jon, Leonardi, Dean K, Lenz, Robert A, Mikol, Daniel D

“…OBJECTIVETo determine the effect of erenumab, a human anti-calcitonin gene-related peptide receptor monoclonal antibody, in patients with chronic migraine and…”
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ARC-CE: updates and plans by Smirnova, Oxana, Kónya, Balázs, Cameron, David, Nilsen, Jon Kerr, Filipčič, Andrej

“…ARC Compute Element is becoming more popular in WLCG and EGI infrastructures, being used not only in the Grid context, but also as an interface to HPC and…”
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Erenumab in chronic migraine: Patient-reported outcomes in a randomized double-blind study by Lipton, Richard B, Tepper, Stewart J, Reuter, Uwe, Silberstein, Stephen, Stewart, Walter F, Nilsen, Jon, Leonardi, Dean K, Desai, Pooja, Cheng, Sunfa, Mikol, Daniel D, Lenz, Robert

“…OBJECTIVETo determine the effect of erenumab, a human monoclonal antibody targeting the calcitonin gene-related peptide receptor, on health-related quality of…”
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Estradiol In Vivo Regulation of Brain Mitochondrial Proteome by Nilsen, Jon, Irwin, Ronald W, Gallaher, Timothy K, Brinton, Roberta Diaz

“…We used a combined proteomic and functional biochemical approach to determine the overall impact of 17beta-estradiol (E2) on mitochondrial protein expression…”
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