Search Results - "NIKKILÄ, Janne"

Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms by Jalanka-Tuovinen, J, Vos, W.M. de

“…While our knowledge of the intestinal microbiota during disease is accumulating, basic information of the microbiota in healthy subjects is still scarce. The…”
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Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine by Wacklin, Pirjo, Mäkivuokko, Harri, Alakulppi, Noora, Nikkilä, Janne, Tenkanen, Heli, Räbinä, Jarkko, Partanen, Jukka, Aranko, Kari, Mättö, Jaana

“…Intestinal microbiota plays an important role in human health, and its composition is determined by several factors, such as diet and host genotype. However,…”
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Faecal microbiota composition in adults is associated with the FUT2 gene determining the secretor status by Wacklin, Pirjo, Tuimala, Jarno, Nikkilä, Janne, Sebastian Tims, Mäkivuokko, Harri, Alakulppi, Noora, Laine, Pia, Rajilic-Stojanovic, Mirjana, Paulin, Lars, de Vos, Willem M, Mättö, Jaana

“…The human intestine is colonised with highly diverse and individually defined microbiota, which likely has an impact on the host well-being. Drivers of the…”
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Comparative metaproteomics and diversity analysis of human intestinal microbiota testifies for its temporal stability and expression of core functions by Kolmeder, Carolin A, de Been, Mark, Nikkilä, Janne, Ritamo, Ilja, Mättö, Jaana, Valmu, Leena, Salojärvi, Jarkko, Palva, Airi, Salonen, Anne, de Vos, Willem M

“…The human intestinal tract is colonized by microbial communities that show a subject-specific composition and a high-level temporal stability in healthy…”
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Microarray analysis reveals marked intestinal microbiota aberrancy in infants having eczema compared to healthy children in at-risk for atopic disease by Nylund, Lotta, Satokari, Reetta, Nikkilä, Janne, Rajilić-Stojanović, Mirjana, Kalliomäki, Marko, Isolauri, Erika, Salminen, Seppo, de Vos, Willem M

“…Deviations in composition and diversity of intestinal microbiota in infancy have been associated with both the development and recurrence of atopic eczema…”
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Comparative analysis of fecal DNA extraction methods with phylogenetic microarray: Effective recovery of bacterial and archaeal DNA using mechanical cell lysis by Salonen, Anne, Nikkilä, Janne, Jalanka-Tuovinen, Jonna, Immonen, Outi, Rajilić-Stojanović, Mirjana, Kekkonen, Riina A., Palva, Airi, de Vos, Willem M.

“…Several different protocols are used for fecal DNA extraction, which is an integral step in all phylogenetic and metagenomic approaches to characterize the…”
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Comparative analysis of pyrosequencing and a phylogenetic microarray for exploring microbial community structures in the human distal intestine by Claesson, M.J, O'Sullivan, O, Wang, Q, Nikkilä, J, Marchesi, J.R, Smidt, H, Vos, W.M. de, Ross, R.P, O'Toole, P.W

“…Variations in the composition of the human intestinal microbiota are linked to diverse health conditions. High-throughput molecular technologies have recently…”
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Association between the ABO blood group and the human intestinal microbiota composition by Mäkivuokko, Harri, Lahtinen, Sampo J, Wacklin, Pirjo, Tuovinen, Elina, Tenkanen, Heli, Nikkilä, Janne, Björklund, Marika, Aranko, Kari, Ouwehand, Arthur C, Mättö, Jaana

“…The mucus layer covering the human intestinal epithelium forms a dynamic surface for host-microbial interactions. In addition to the environmental factors…”
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Cytokine response of human mononuclear cells induced by intestinal Clostridium species by Tuovinen, Elina, Keto, Joni, Nikkilä, Janne, Mättö, Jaana, Lähteenmäki, Kaarina

“…Altered composition of intestinal microbiota has been associated with various immunological disorders such as inflammatory bowel disease. Although Clostridium…”
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Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality[S] by Kilpinen, Lotta, Tigistu-Sahle, Feven, Oja, Sofia, Greco, Dario, Parmar, Amarjit, Saavalainen, Päivi, Nikkilä, Janne, Korhonen, Matti, Lehenkari, Petri, Käkelä, Reijo, Laitinen, Saara

“…Human mesenchymal stem/stromal cells (hMSC) are increasingly used in advanced cellular therapies. The clinical use of hMSCs demands sequential cell expansions…”
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Metabolic regulation in progression to autoimmune diabetes by Sysi-Aho, Marko, Ermolov, Andrey, Gopalacharyulu, Peddinti V, Tripathi, Abhishek, Seppänen-Laakso, Tuulikki, Maukonen, Johanna, Mattila, Ismo, Ruohonen, Suvi T, Vähätalo, Laura, Yetukuri, Laxman, Härkönen, Taina, Lindfors, Erno, Nikkilä, Janne, Ilonen, Jorma, Simell, Olli, Saarela, Maria, Knip, Mikael, Kaski, Samuel, Savontaus, Eriika, Orešič, Matej

“…Recent evidence from serum metabolomics indicates that specific metabolic disturbances precede β-cell autoimmunity in humans and can be used to identify those…”
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Effect of a multispecies probiotic supplement on quantity of irritable bowel syndrome-related intestinal microbial phylotypes by Lyra, Anna, Krogius-Kurikka, Lotta, Nikkilä, Janne, Malinen, Erja, Kajander, Kajsa, Kurikka, Kyösti, Korpela, Riitta, Palva, Airi

“…Probiotics can alleviate the symptoms of irritable bowel syndrome (IBS), possibly by stabilizing the intestinal microbiota. Our aim was to determine whether…”
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Transient Proteolytic Modification of Mesenchymal Stromal Cells Increases Lung Clearance Rate and Targeting to Injured Tissue by Kerkelä, Erja, Hakkarainen, Tanja, Mäkelä, Tuomas, Raki, Mari, Kambur, Oleg, Kilpinen, Lotta, Nikkilä, Janne, Lehtonen, Siri, Ritamo, Ilja, Pernu, Roni, Pietilä, Mika, Takalo, Reijo, Juvonen, Tatu, Bergström, Kim, Kalso, Eija, Valmu, Leena, Laitinen, Saara, Lehenkari, Petri, Nystedt, Johanna

“…This study showed that an alternative cell detachment of mesenchymal stromal/stem cells (MSCs) with pronase instead of trypsin significantly accelerated the…”
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Trustworthiness and metrics in visualizing similarity of gene expression by Kaski, Samuel, Nikkilä, Janne, Oja, Merja, Venna, Jarkko, Törönen, Petri, Castrén, Eero

“…Conventionally, the first step in analyzing the large and high-dimensional data sets measured by microarrays is visual exploration. Dendrograms of hierarchical…”
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Gut microbiota of healthy elderly NSAID users is selectively modified with the administration of Lactobacillus acidophilus NCFM and lactitol by Björklund, Marika, Ouwehand, Arthur C., Forssten, Sofia D., Nikkilä, Janne, Tiihonen, Kirsti, Rautonen, Nina, Lahtinen, Sampo J.

“…Ageing changes gut microbiota composition and alters immune system function. Probiotics, prebiotics and synbiotics may improve the health status of elderly…”
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Analysis and visualization of gene expression data using Self-Organizing Maps by Nikkilä, Janne, Törönen, Petri, Kaski, Samuel, Venna, Jarkko, Castrén, Eero, Wong, Garry

“…Cluster structure of gene expression data obtained from DNA microarrays is analyzed and visualized with the Self-Organizing Map (SOM) algorithm. The SOM forms…”
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Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians by Biagi, E, Nylund, L, Candela, M, Ostan, R, Bucci, L, Pini, E, Nikkïla, J, Monti, D, Satokari, R.M, Franceschi, C, Brigidi, P, Vos, W.M. de

“…Age-related physiological changes in the gastrointestinal tract, as well as modifications in lifestyle, nutritional behaviour, and functionality of the host…”
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Gender-dependent progression of systemic metabolic states in early childhood by Simell, Olli, Kaski, Samuel, Sysi-Aho, Marko, Nikkilä, Janne, Ermolov, Andrey, Seppänen-Laakso, Tuulikki, Oreši, Matej

“…Little is known about the human intra‐individual metabolic profile changes over an extended period of time. Here, we introduce a novel concept suggesting that…”
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A global map of human gene expression by Brazma, Alvis, Lukk, Margus, Kapushesky, Misha, Nikkilä, Janne, Parkinson, Helen, Goncalves, Angela, Huber, Wolfgang, Ukkonen, Esko

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Association of symptoms with gastrointestinal microbiota in irritable bowel syndrome by Malinen, Erja, Krogius-Kurikka, Lotta, Lyra, Anna, Nikkilä, Janne, Jääskeläinen, Anne, Rinttilä, Teemu, Vilpponen-Salmela, Terttu, von Wright, Atte Johannes, Palva, Airi

“…To investigate the correlations between self-reported symptoms of irritable bowel syndrome (IBS) and the gastrointestinal (GI) microbiota composition. Fecal…”
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