Search Results - "NIGRO, J. M"
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In vivo models of primary brain tumors: pitfalls and perspectives
Published in Neuro-oncology (Charlottesville, Va.) (01-08-2012)“…Animal modeling for primary brain tumors has undergone constant development over the last 60 years, and significant improvements have been made recently with…”
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Scrambled exons
Published in Cell (08-02-1991)“…Using a sensitive assay for RNA expression, we identified several abnormally spliced transcripts in which exons from a candidate tumor suppressor gene (DCC)…”
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Mutations in the p53 gene occur in diverse human tumour types
Published in Nature (London) (07-12-1989)“…The p53 gene has been a constant source of fascination since its discovery nearly a decade ago. Originally considered to be an oncogene, several convergent…”
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Identification of a Chromosome 18q Gene That is Altered in Colorectal Cancers
Published in Science (American Association for the Advancement of Science) (05-01-1990)“…Allelic deletions involving chromosome 18q occur in more than 70 percent of colorectal cancers. Such deletions are thought to signal the existence of a tumor…”
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Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae
Published in Molecular and Cellular Biology (01-03-1992)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cellular adhesion regulates p53 protein levels in primary human keratinocytes
Published in Cancer research (Chicago, Ill.) (01-09-1997)“…To gain insight into p53 tissue-specific regulatory pathways and biological activities, we investigated mechanisms that may account for the elevated levels of…”
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Detection of 1p and 19q Loss in Oligodendroglioma by Quantitative Microsatellite Analysis, a Real-Time Quantitative Polymerase Chain Reaction Assay
Published in The American journal of pathology (01-04-2001)“…The combined loss of chromosomes 1p and 19q has recently emerged as a genetic predictor of chemosensitivity in anaplastic oligodendrogliomas. Here, we describe…”
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Expression of rabbit ventricular alpha-myosin heavy chain messenger RNA sequences in atrial muscle
Published in The Journal of biological chemistry (25-05-1984)“…We have constructed and isolated a cardiac myosin heavy chain (HC) cDNA clone, pMHC alpha 81, with mRNA from ventricular heart muscle of hyperthyroid rabbits…”
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cDNA cloning and mapping of the human creatine kinase M gene to 19q13
Published in American journal of human genetics (01-02-1987)“…We describe the first isolation of a human creatine kinase M cDNA clone and its mapping of the gene to human chromosome 19. A human creatine kinase M cDNA…”
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PCR-based detection of two MspI polymorphic sites at D18S8
Published in Nucleic acids research (25-12-1991)Get full text
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Analysis of cloned mRNA sequences encoding subfragment 2 and part of subfragment 1 of alpha- and beta-myosin heavy chains of rabbit heart
Published in The Journal of biological chemistry (10-03-1984)“…Two cardiac myosin heavy chain cDNA clones, pMHC alpha 252 and pMHC beta 174, were constructed using rabbit ventricular mRNA isolated from adult thyrotoxic and…”
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Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas
Published in Science (American Association for the Advancement of Science) (14-04-1989)“…Previous studies have demonstrated that allelic deletions of the short arm of chromosome 17 occur in over 75% of colorectal carcinomas. Twenty chromosome 17p…”
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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
Published in Cancer cell (01-03-2006)“…Previously undescribed prognostic subclasses of high-grade astrocytoma are identified and discovered to resemble stages in neurogenesis. One tumor class…”
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Integrated array-comparative genomic hybridization and expression array profiles identify clinically relevant molecular subtypes of glioblastoma
Published in Cancer research (Chicago, Ill.) (01-03-2005)“…Glioblastoma, the most aggressive primary brain tumor in humans, exhibits a large degree of molecular heterogeneity. Understanding the molecular pathology of a…”
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Representing Experience on Road Accident Management
Published in 2012 IEEE 21st International Workshop on Enabling Technologies: Infrastructure for Collaborative Enterprises (01-06-2012)“…Crisis management is a special type of collaborative situation in which the actors are subject to an uninterrupted stress. To deal with the important…”
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Analysis of resurgent sodium-current expression in rat parahippocampal cortices and hippocampal formation
Published in Brain research (13-08-2007)“…Abstract The resurgent Na+ current ( INaR ) is a component of neuronal voltage-dependent Na+ currents that is activated by repolarization and is believed to…”
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An Apology or Absolution for Cerebral Near Infrared Spectroscopy: Can We Get on the Same Wavelength?
Published in The Journal of thoracic and cardiovascular surgery (01-09-2017)Get full text
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Mutant p53 proteins bind DNA abnormally in vitro
Published in Oncogene (01-01-1991)“…The p53 gene encodes a phosphoprotein which binds DNA. Many types of tumors contain mutant p53 genes, but the effects of these mutations on the intrinsic…”
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An evidential cooperative multi-agent system
Published in Expert systems with applications (01-02-2006)“…The cooperative learning systems (COLS) are an interesting way of research in Artificial Intelligence. This is because an intelligence form can emerge by…”
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