Search Results - "NIGHTINGALE, Charles H"

Population Pharmacokinetic Analysis and Dosing Regimen Optimization of Meropenem in Adult Patients by Li, Chonghua, Kuti, Joseph L., Nightingale, Charles H., Nicolau, David P.

“…The objectives of this study were to develop a meropenem population pharmacokinetic model using patient data and use it to explore alternative dosage regimens…”
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Impact of Extended‐Spectrum β‐Lactamase–Producing Escherichia coli and Klebsiella Species on Clinical Outcomes and Hospital Costs: A Matched Cohort Study by Lee, Su Young, Kotapati, Srividya, Kuti, Joseph L., Nightingale, Charles H., Nicolau, David P.

“…To evaluate the economic and clinical impact of infection with extended-spectrum beta -lactamase (ESBL)-producing Escherichia coli and Klebsiella species…”
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Optimizing Pharmacodynamic Target Attainment Using the MYSTIC Antibiogram: Data Collected in North America in 2002 by KUTI, Joseph L, NIGHTINGALE, Charles H, NICOLAU, David P

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Use of Monte Carlo Simulation to Design an Optimized Pharmacodynamic Dosing Strategy for Meropenem by Kuti, Joseph L., Dandekar, Prachi K., Nightingale, Charles H., Nicolau, David P.

“…Prolonging the infusion of meropenem over 3 hours increases the percentage of the dosing interval that drug concentrations remain above the minimum inhibitory…”
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Adherence to Highly Active Antiretroviral Therapy Predicts Virologic Outcome at an Inner-City Human Immunodeficiency Virus Clinic by McNabb, JoCarol, Ross, Jack W., Abriola, Kenneth, Turley, Christina, Nightingale, Charles H., Nicolau, David P.

“…This study's hypothesis is that human immunodeficiency virus—infected patients in the inner city (predominantly injection drug users and ethnic minorities) do…”
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Tissue Penetration of Telavancin after Intravenous Administration in Healthy Subjects by SUN, Heather K, DUCHIN, Kenneth, NIGHTINGALE, Charles H, SHAW, Jeng-Pyng, SEROOGY, Julie, NICOLAU, David P

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Pharmacokinetic Profile of Tigecycline in Serum and Skin Blister Fluid of Healthy Subjects after Multiple Intravenous Administrations by SUN, Heather K, ONG, Christine T, UMER, Ambreen, HARYER, Dawn, TROY, Steven, NIGHTINGALE, Charles H, NICOLAU, David P

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Pharmacodynamic Comparisons of Levofloxacin, Ciprofloxacin, and Ampicillin against Streptococcus pneumoniae in an In Vitro Model of Infection by LACY, M. K, WEN LU, XIAOWEI XU, TESSIER, P. R, NICOLAU, D. P, QUINTILIANI, R, NIGHTINGALE, C. H

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Determination of the In Vivo Pharmacodynamic Profile of Cefepime against Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli at Various Inocula by MAGLIO, Dana, ONG, Christine, BANEVICIUS, Mary Anne, GENG, Qiuming, NIGHTINGALE, Charles H, NICOLAU, David P

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Cost Effect of Managing Methicillin-Resistant Staphylococcus Aureus in a Long-Term Care Facility by Capitano, Blair, Leshem, O. Alice, Nightingale, Charles H., Nicolau, David P.

“…OBJECTIVES: The purpose of this study was to measure the total consumption of resources involved in the care of a long‐term care facility (LTCF) resident…”
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Penetration, efflux and intracellular activity of tigecycline in human polymorphonuclear neutrophils (PMNs) by Ong, Christine T., Babalola, Chinedum P., Nightingale, Charles H., Nicolau, David P.

“…Objectives: To evaluate the penetration, efflux and intracellular activity of tigecycline in human polymorphonuclear neutrophils (PMNs). Methods: PMNs were…”
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The Pharmacodynamics of Aminoglycosides by Lacy, Melinda K., Nicolau, David P., Nightingale, Charles H., Quintiliani, Richard

“…Recently, a more complete understanding of the pharmacodynamics of aminoglycosides has been recognized, indicating that this class of antibiotics exhibits both…”
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Population Pharmacokinetics and Pharmacodynamics of Meropenem in Pediatric Patients by Du, Xiaoli, Li, Chonghua, Kuti, Joseph L., Nightingale, Charles H., Nicolau, David P.

“…Meropenem is a highly potent carbapenem antibiotic against gram‐positive and gram‐negative bacteria. Meropenem plasma concentration data from 99 pediatric…”
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Pharmacodynamic Assessment of Clarithromycin in a Murine Model of Pneumococcal Pneumonia by TESSIER, Pamela R, KIM, Myo-Kyoung, WEN ZHOU, DAWEI XUAN, CHONGHUA LI, MIN YE, NIGHTINGALE, Charles H, NICOLAU, David P

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Pharmacodynamics of Moxifloxacin and Levofloxacin at Simulated Epithelial Lining Fluid Drug Concentrations against Streptococcus pneumoniae by FLOREA, Naomi R, TESSIER, Pamela R, CUILIAN ZHANG, NIGHTINGALE, Charles H, NICOLAU, David P

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Quantitation of tigecycline, a novel glycyclcycline, by liquid chromatography by CHONGHUA LI, SUTHERLAND, Christina A, NIGHTINGALE, Charles H, NICOLAU, David P

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Pharmacodynamic Profile of Ertapenem against Klebsiella pneumoniae and Escherichia coli in a Murine Thigh Model by MAGLIO, Dana, BANEVICIUS, Mary Anne, SUTHERLAND, Christina, BABALOLA, Chinedum, NIGHTINGALE, Charles H, NICOLAU, David P

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Comparison of Pharmacodynamic Target Attainment Between Healthy Subjects and Patients for Ceftazidime and Meropenem by Kuti, Joseph L., Horowitz, Sheryl, Nightingale, Charles H., Nicolau, David P.

“…Study Objective. To compare the pharmacodynamics of two β‐lactams—ceftazidime and meropenem—in healthy subjects versus patients. Design. Monte Carlo simulation…”
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Pharmacodynamic Profile of Telithromycin against Macrolide- and Fluoroquinolone-Resistant Streptococcus pneumoniae in a Neutropenic Mouse Thigh Model by TESSIER, Pamela R, MATTOES, Holly M, DANDEKAR, Prachi K, NIGHTINGALE, Charles H, NICOLAU, David P

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Pharmacodynamics of Meropenem and Imipenem Against Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa by Kuti, Joseph L., Florea, Naomi R., Nightingale, Charles H., Nicolau, David P.

“…Study Objective. To compare the pharmacodynamics of meropenem and imipenem, both administered as 500 mg every 6 hours, against populations of…”
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