Search Results - "NIES, ALAN S"

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    Effect of acetylator phenotype on the rate at which procainamide induces antinuclear antibodies and the lupus syndrome by Woosley, R L, Drayer, D E, Reidenberg, M M, Nies, A S, Carr, K, Oates, J A

    Published in The New England journal of medicine (25-05-1978)
    “…To investigate the relation between acetvlator phenotype and the development of procainamide-induced lupus, we determined the rate of development of…”
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    Contribution of Kinins to Endotoxin Shock in Unanesthetized Rhesus Monkeys by Nies, Alan S, Forsyth, Ralph P, Williams, Hibbard E, Melmon, Kenneth L

    Published in Circulation research (01-02-1968)
    “…The effects of endotoxin (Escherichia coli and Pseudomonas pseudomallei) were studied in 18 unanesthetized rhesus monkeys restrained in primate chairs…”
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    The role of adenosine in promoting cardiac beta-adrenergic subsensitivity in aging humans by Suteparuk, S, Nies, A S, Andros, E, Gerber, J G

    “…The mechanism by which aging decreases the cardiac chronotropic response in human subjects is unknown. We investigated the role of endogenous adenosine in…”
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    Organophosphate Poisoning From Wearing a Laundered Uniform Previously Contaminated With Parathion by Clifford, Nathan J, Nies, Alan S

    “…THE ORGANOPHOSPHATE pesticides came into widespread use because they do not persist in the area of application as do organochlorine pesticides such as…”
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    The hypotensive action of captopril and enalapril is not prostacyclin dependent by Gerber, J G, Franca, G, Byyny, R L, LoVerde, M, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-11-1993)
    “…Angiotensin converting enzyme inhibitors have been proposed to have a prostaglandin-dependent component to their hypotensive action. The aim of this study was…”
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    The antihypertensive efficacy of hydrochlorothiazide is not prostacyclin dependent by Gerber, J G, LoVerde, M, Byyny, R L, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-10-1990)
    “…We tested the hypothesis that vascular prostacyclin synthesis is stimulated by hydrochlorothiazide and could account for some of the drug's antihypertensive…”
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    Beta-adrenergic receptors in the elderly are not less sensitive to timolol by Klein, C, Gerber, J G, Gal, J, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-08-1986)
    “…The elderly have been reported to be less sensitive to the beta-adrenergic blocking effect of propranolol. However, propranolol is a racemate, and age-related…”
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    Sulindac is not renal sparing in man by Roberts, D G, Gerber, J G, Barnes, J S, Zerbe, G O, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-09-1985)
    “…We investigated the claimed renal-sparing effect of the cyclooxygenase inhibitor sulindac. Fifteen normal women following a diet of 50 mEq salt a day were…”
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    The balance between vascular alpha- and beta-adrenoceptors is not changed in the elderly by Klein, C, Hiatt, W R, Gerber, J G, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-09-1987)
    “…It has been suggested that beta-adrenoceptor-mediated functions are diminished with aging and that these responses are reduced to a greater extent than are…”
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    Lack of an effect of age on the response to clonidine by Klein, C E, Gerber, J G, Nies, A S

    Published in Clinical pharmacology and therapeutics (01-01-1990)
    “…The plasma concentration and appearance rate of norepinephrine are increased in the elderly. A hypothesis to explain this observation is that the elderly have…”
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    A double-blind, randomized, controlled trial comparing pinacidil to hydralazine in essential hypertension by Byyny, R L, Nies, A S, LoVerde, M E, Mitchell, W D

    Published in Clinical pharmacology and therapeutics (01-07-1987)
    “…Pinacidil is a direct vasodilator with good absorption, a half-life of 2 to 4 hours, and side effects similar to those of other vasodilators. We hypothesized…”
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    Interaction of quinidine with anticonvulsant drugs by Data, J L, Wilkinson, G R, Nies, A S

    Published in The New England journal of medicine (25-03-1976)
    “…Drug-disposition studies of orally administered quinidine in four normal healthy volunteers indicated that phenobarbital and phenytoin reduced the half-life of…”
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    beta-2 Adrenergic blockade evaluated with epinephrine after placebo, atenolol, and nadolol by Hiatt, W R, Wolfel, E E, Stoll, S, Nies, A S, Zerbe, G O, Brammell, H L, Horwitz, L D

    Published in Clinical pharmacology and therapeutics (01-01-1985)
    “…Vascular beta 2-adrenergic blocking effects of the water-soluble drugs atenolol (beta 1-selective) and nadolol (nonselective) were evaluated. Twenty-four…”
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