Search Results - "NIELSEN, Thorbjørn Terndrup"
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Supramolecular Complexes of Plant Neurotoxin Veratridine with Cyclodextrins and Their Antidote-like Effect on Neuro-2a Cell Viability
Published in Pharmaceutics (09-03-2022)“…Veratridine (VTD) is a plant neurotoxin that acts by blocking the voltage-gated sodium channels (VGSC) of cell membranes. Symptoms of VTD intoxication include…”
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Surface modification using self-assembled layers of amphiphilic cyclodextrins
Published in Journal of applied polymer science (15-11-2014)“…ABSTRACT In this study six amphiphilic cyclodextrin derivatives were prepared by esterification and used to coat five industrial products made from…”
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3
HiLiDeSystematic Approach to Membrane Protein Crystallization in Lipid and Detergent
Published in Crystal growth & design (01-06-2011)“…To obtain the initial crystallization hit and the subsequent optimization remain the major bottlenecks in membrane protein structure determination. Here we…”
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Size-Controlled Nanoassemblies Based on Cyclodextrin-Modified Dextrans
Published in Macromolecular bioscience (09-09-2011)“…Nanoassemblies formed by host/guest interactions between two polymers in aqueous media are studied. Two types of polymers with the same dextran backbone are…”
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Formation of nanoparticles by cooperative inclusion between (S)-camptothecin-modified dextrans and β-cyclodextrin polymers
Published in Beilstein journal of organic chemistry (21-01-2015)“…Novel (S)-camptothecin-dextran polymers were obtained by "click" grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on…”
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Facile Synthesis of β-Cyclodextrin-Dextran Polymers by “Click” Chemistry
Published in Biomacromolecules (12-07-2010)“…Three series of novel water-soluble β-cyclodextrin-dextran polymers have been prepared by “click” chemistry. The polymers were synthesized from alkyne-modified…”
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β-Cyclodextrin-dextran polymers for the solubilization of poorly soluble drugs
Published in International journal of pharmaceutics (01-07-2014)“…[Display omitted] The aim of this study was to assess the potential of novel β-cyclodextrin (βCD)-dextran polymers for drug delivery. The size distribution of…”
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β-CD-dextran polymer for efficient sequestration of cholesterol from phospholipid bilayers: Mechanistic and safe-toxicity investigations
Published in International journal of pharmaceutics (30-12-2015)“…[Display omitted] The aim of this work was to investigate the suitability of β-cyclodextrin-dextran (BCD-dextran) polymer as cholesterol sequestering agent in…”
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Direct synthesis of well-defined zwitterionic cyclodextrin polymers via atom transfer radical polymerization
Published in European polymer journal (01-07-2019)“…[Display omitted] •A β-cyclodextrin monomer is synthesized with excellent yield using “click” chemistry.•An ATRP protocol for the direct synthesis of…”
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10
High performance ultra- and nanofiltration removal of micropollutants by cyclodextrin complexation
Published in Chemical engineering research & design (01-12-2022)“…Nanofiltration is a promising solution for the removal of emerging and persistent micropollutants, but it is limited by operating expenses due to high membrane…”
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Supramolecular Solubilization of Cyclodextrin-Modified Carbon Nano-Onions by Host–Guest Interactions
Published in Langmuir (13-01-2015)“…Small carbon nano-onions (CNOs, 6–12 shells) were prepared in high yields and functionalized with carboxylic groups by chemical oxidation and reacted with…”
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Self-assembled nanoparticles based on cyclodextrin-modified pullulan: Synthesis, and structural characterization using SAXS
Published in Carbohydrate polymers (01-06-2019)“…[Display omitted] •Pullulan was modified with β-cyclodextrin via “click” chemistry.•Nanoparticles were created via self-assembly with an adamantane-modified…”
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Template-Assisted Preparation of Permeable Nanocapsules from Complementary Cyclodextrin and Adamantane-Appended Biocompatible Dextran Polymers
Published in Macromolecular materials and engineering (01-09-2015)“…Supramolecular host‐guest interactions are an attractive driving force for the preparation of two‐ and three‐dimensional materials. In this work, the…”
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14
Site-specific photocoupling of pBpa mutated scFv antibodies for use in affinity proteomics
Published in Biochimica et biophysica acta. Proteins and proteomics (01-08-2017)“…Recombinant antibody libraries can provide a source of renewable and high-performing binders tailored for use in affinity proteomics. In this context, the…”
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15
Preparation and characterization of a temperature-sensitive nonwoven poly(propylene) with increased affinity for guest molecules
Published in Journal of applied polymer science (05-07-2014)“…ABSTRACT A temperature‐sensitive hydrogel with the capability of inclusion complex formation with guest molecules was successfully grafted onto the surface of…”
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Synthesis and characterization of poly(ethylene glycol) based β-cyclodextrin polymers
Published in Journal of Inclusion Phenomena and Macrocyclic Chemistry (01-12-2009)“…A series of novel water soluble β-cyclodextrin (βCD) polymers has been synthesized from functionalized poly(ethylene glycol) (PEG). The chemical composition of…”
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Tailorable Polymeric Assemblies Based on Host/Guest Interactions Between Modified Dextrans
Published in Macromolecular symposia. (01-08-2012)“…Nanoassemblies are spontaneously formed in dilute aqueous solutions by mixing of two dextrans modified with lauroyl and β‐cyclodextrin moieties, respectively…”
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Synthesis of β‑Cyclodextrin Diazonium Salts and Electrochemical Immobilization onto Glassy Carbon and Gold Surfaces
Published in Langmuir (11-12-2012)“…This study shows that diazotized β-cyclodextrin (β-CD) can be produced, isolated, and immobilized onto glassy carbon and gold surfaces…”
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Drug loading in cyclodextrin polymers: dexamethasone model drug
Published in Journal of Inclusion Phenomena and Macrocyclic Chemistry (01-04-2011)“…In pharmaceutical formulations cyclodextrins (CDs) are used to improve the aqueous solubility, stability, dissolution rate, bioavailability and/or local…”
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Solving the puzzle of 2-hydroxypropyl β-cyclodextrin: Detailed assignment of the substituent distribution by NMR spectroscopy
Published in Carbohydrate polymers (15-08-2024)“…2-Hydroxypropyl-β-cyclodextrin (HPBCD) is one of the most important cyclodextrin derivatives, finding extensive applications in the pharmaceutical sector…”
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