Search Results - "NICOLAOU, Persoulla"

Sex differences in heart failure medications targeting the renin-angiotensin-aldosterone system by Nicolaou, Persoulla A.

“…Heart failure (HF) is a major healthcare problem. Sex-related differences in clinical manifestations, outcomes, risk factors and symptoms in HF have been…”
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The Impact of Using Virtual Patients in Preclinical Pharmacology Teaching by Nicolaou, Persoulla A, El Saifi, Mamoun

“…To reduce medication errors, medical educators must nurture the early development of rational and safe prescribing. Teaching pharmacology is challenging…”
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Development of a leadership and management module for the undergraduate medical curriculum by Nicolaou, Nicoletta, Nicolaou, Cornelia, Nicolaou, Persoulla, Nicolaides, Paola, Papageorgiou, Alexia

“…Background Physicians play an important role in management and governance of healthcare systems, yet many lack formal leadership training and skills. Despite…”
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MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20 by REN, Xiao-Ping, JINGHAI WU, XIAOHONG WANG, SARTOR, Maureen A, JIANG QIAN, JONES, Keith, NICOLAOU, Persoulla, PRITCHARD, Tracy J, FAN, Guo-Chang

“…Recent studies have identified critical roles for microRNAs (miRNAs) in a variety of cellular processes, including regulation of cardiomyocyte death. However,…”
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Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology by Nicolaou, Persoulla, Hajjar, Roger J, Kranias, Evangelia G

“…Abstract The type 1 protein phosphatase (PP1) is a critical negative regulator of Ca2+ cycling and contractility in the cardiomyocyte. In particular, it…”
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Factors affecting pharmacology learning in integrated PBL in diverse medical students: a mixed methods study by Nicolaou, S A, Televantou, I, Papageorgiou, A, Albert, A P, Hitchings, A W, McCrorie, P, Nicolaou, Persoulla

“…Problem-based learning (PBL) was introduced to address passive teaching limitations. However, it is not fully characterised as a teaching modality in…”
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Impact of the morphological properties of thin TiO2 photocatalytic films on the detoxification of water contaminated with the cyanotoxin, microcystin-LR by Antoniou, Maria G., Nicolaou, Persoulla A., Shoemaker, Jody A., de la Cruz, Armah A., Dionysiou, Dionysios D.

“…This study investigated the use of thin transparent TiO2 photocatalytic films, prepared with novel sol–gel methods containing surfactants as templating…”
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Inducible Expression of Active Protein Phosphatase-1 Inhibitor-1 Enhances Basal Cardiac Function and Protects Against Ischemia/Reperfusion Injury by Nicolaou, Persoulla, Rodriguez, Patricia, Ren, Xiaoping, Zhou, Xiaoyang, Qian, Jiang, Sadayappan, Sakthivel, Mitton, Bryan, Pathak, Anand, Robbins, Jeffrey, Hajjar, Roger J, Jones, Keith, Kranias, Evangelia G

“…Ischemic heart disease, which remains the leading cause of morbidity and mortality in the Western world, is invariably characterized by impaired cardiac…”
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Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury by FAN, Guo-Chang, XIAOPING REN, JIANG QIAN, QUNYING YUAN, NICOLAOU, Persoulla, YANG WANG, JONES, W. Keith, GUOXIANG CHU, KRANIAS, Evangelia G

“…Heat-shock proteins (Hsps) have been shown to render cardioprotection from stress-induced injury; however, little is known about the role of another small…”
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Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts by Pritchard, Tracy J, Kawase, Yoshiaki, Haghighi, Kobra, Anjak, Ahmad, Cai, Wenfeng, Jiang, Min, Nicolaou, Persoulla, Pylar, George, Karakikes, Ioannis, Rapti, Kleopatra, Rubinstein, Jack, Hajjar, Roger J, Kranias, Evangelia G

“…Impaired sarcoplasmic reticulum calcium cycling and depressed contractility are key characteristics in heart failure. Defects in sarcoplasmic reticulum…”
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Human Mutation in the Anti-apoptotic Heat Shock Protein 20 Abrogates Its Cardioprotective Effects by Nicolaou, Persoulla, Knöll, Ralph, Haghighi, Kobra, Fan, Guo-Chang, Dorn, Gerald W., Hasenfuß, Gerd, Kranias, Evangelia G.

“…The small heat shock protein Hsp20 protects cardiomyocytes against apoptosis, and phosphorylation at its Ser16 site enhances its cardioprotection. To determine…”
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Phosphorylation of human inhibitor-1 at Ser67 and/or Thr75 attenuates stimulatory effects of protein kinase A signaling in cardiac myocytes by Rodriguez, Patricia, Mitton, Bryan, Nicolaou, Persoulla, Chen, Guoli, Kranias, Evangelia G

“…The depressed function of failing hearts has been partially attributed to increased protein phosphatase-1 through its impaired regulation by inhibitor-1…”
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Transforming a cookbook undergraduate microbiology laboratory to inquiry based using a semester-long PBL case study by Nicolaidou, Vicky, Nicolaou, Persoulla, Nicolaou, Stella A

“…Microbial physiology is a basic course taught throughout biomedical science disciplines. Students study the structure, growth, and metabolism of microorganisms…”
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Using virtual patients to integrate physiology, pathophysiology, and pharmacology in preclinical teaching by Nicolaou, Persoulla, McCrorie, Peter, Nicolaou, Stella A

“…Nicolaou et al discuss the use of virtual patients to integrate physiology, pathophysiology, and pharmacology in preclinical teaching. To address the…”
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Heat Shock Protein 20 Interacting With Phosphorylated Akt Reduces Doxorubicin-Triggered Oxidative Stress and Cardiotoxicity by Fan, Guo-Chang, Zhou, Xiaoyang, Wang, Xiaohong, Song, Guojie, Qian, Jiang, Nicolaou, Persoulla, Chen, Guoli, Ren, Xiaoping, Kranias, Evangelia G

“…Doxorubicin (DOX) is a widely used antitumor drug, but its application is limited because of its cardiotoxic side effects. Heat shock protein (Hsp)20 has been…”
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Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6S10F mutant by Liu, Guan-Sheng, Zhu, Hongyan, Cai, Wen-Feng, Wang, Xiaohong, Jiang, Min, Essandoh, Kobina, Vafiadaki, Elizabeth, Haghighi, Kobra, Lam, Chi Keung, Gardner, George, Adly, George, Nicolaou, Persoulla, Sanoudou, Despina, Liang, Qiangrong, Rubinstein, Jack, Fan, Guo-Chang, Kranias, Evangelia G.

“…HSPB6/Hsp20 (heat shock protein family B [small] member 6) has emerged as a novel cardioprotector against stress-induced injury. We identified a human mutant…”
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Establishing and Evaluating a Study Questionnaire on Knowledge and Attitudes of Healthcare Professionals Towards Recreational and Medical Cannabis Across Europe by Jouanjus, Emilie, Sans-Pola, Carla, Mainoli, Beatrice, Javid, Farideh A., Ekheden, Isabella

“…Background and Objective The present survey was a preliminary to a European research project on the attitude and knowledge of healthcare professionals towards…”
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Role of PP1 in the regulation of Ca cycling in cardiac physiology and pathophysiology by Nicolaou, Persoulla, Kranias, Evangelia G

“…Type 1 protein phosphatase (PP1) is a critical regulator of several cellular processes. In the heart, it mediates restoration of contractility to basal levels…”
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Regulation of BECN1-mediated autophagy by HSPB6: Insights from a human HSPB6 S10F mutant by Liu, Guan-Sheng, Zhu, Hongyan, Cai, Wen-Feng, Wang, Xiaohong, Jiang, Min, Essandoh, Kobina, Vafiadaki, Elizabeth, Haghighi, Kobra, Lam, Chi Keung, Gardner, George, Adly, George, Nicolaou, Persoulla, Sanoudou, Despina, Liang, Qiangrong, Rubinstein, Jack, Fan, Guo-Chang, Kranias, Evangelia G

“…HSPB6/Hsp20 (heat shock protein family B [small] member 6) has emerged as a novel cardioprotector against stress-induced injury. We identified a human mutant…”
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Impact of the morphological properties of thin TiO(2) photocatalytic films on the detoxification of water contaminated with the cyanotoxin, microcystin-LR by Antoniou, Maria G, Nicolaou, Persoulla A, Shoemaker, Jody A, De la Cruz, Armah A., Dionysiou, Dionysios D

“…This study investigated the use of thin transparent TiO(2) photocatalytic films, prepared with novel sol-gel methods containing surfactants as templating…”
Get full text