Search Results - "NICOL, Gordon"

Use of an Immunoaffinity-Mass Spectrometry-based Approach for the Quantification of Protein Biomarkers from Serum Samples of Lung Cancer Patients by Nicol, Gordon R., Han, Mark, Kim, Jun, Birse, Charles E., Brand, Erin, Nguyen, Anh, Mesri, Mehdi, FitzHugh, William, Kaminker, Patrick, Moore, Paul A., Ruben, Steven M., He, Tao

“…It is a challenging task to verify and quantify potential biomarkers expressed at elevated levels in sera from cancer patients. An immunoaffinity-mass…”
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Differences among techniques for high-abundant protein depletion by Zolotarjova, Nina, Martosella, James, Nicol, Gordon, Bailey, Jerome, Boyes, Barry E., Barrett, William C.

“…The need to identify protein or peptide biomarkers via readily available biological samples like serum, plasma, or cerebrospinal fluid is often hindered by a…”
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Reversed-Phase High-Performance Liquid Chromatographic Prefractionation of Immunodepleted Human Serum Proteins to Enhance Mass Spectrometry Identification of Lower-Abundant Proteins by Martosella, James, Zolotarjova, Nina, Liu, Hongbin, Nicol, Gordon, Boyes, Barry E

“…Serum analysis represents an extreme challenge due to the dynamic range of the proteins of interest, and the high structural complexity of the constituent…”
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Improved Mass Spectrometric Characterization of Protein Glycosylation Reveals Unusual Glycosylation of Maize-Derived Bovine Trypsin by Zhang, Hao, Huang, Richard Y−C, Jalili, Pegah R, Irungu, Janet W, Nicol, Gordon R, Ray, Kevin B, Rohrs, Henry W, Gross, Michael L

“…Although bottom-up proteomics using tryptic digests is widely used to locate post-translational modifications (PTM) in proteins, there are cases where the…”
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The Use of Deuterium Oxide as a Mobile Phase for Structural Elucidation by HPLC/UV/ESI/MS by Olsen, Mark A, Cummings, Paul G, Kennedy-Gabb, Sonya, Wagner, Brian M, Nicol, Gordon R, Munson, Burnaby

“…The use of deuterium oxide as a mobile phase in the routine analysis of pharmaceutical compounds was investigated. The deuterium exchange of labile hydrogen…”
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Proton affinities of saturated aliphatic methyl esters by Evans, Jason, Nicol, Gordon, Munson, Burnaby

“…The kinetic method was used to determine the proton affinities of methyl esters of several saturated fatty acids. Decompositions of the proton-bound dimers of…”
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Factors determining relative sensitivity of analytes in positive mode atmospheric pressure ionization mass spectrometry by Sunner, Jan, Nicol, Gordon, Kebarle, Paul

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Gas Chromatography/Mass Spectrometry of Polyethylene Glycol Oligomers by Onigbinde, Adebayo, Nicol, Gordon, Munson, Burnaby

“…Polyethylene glycol (PEG) oligomers, H(OC2H4O)nH, were analyzed by gas chromatography/mass spectrometry (GC/MS) for oligomers, n = 2–11, without indications of…”
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Rapid Polymer Identification by In-Source Direct Pyrolysis Mass Spectrometry and Library Searching Techniques by Qian, Kuangnan, Killinger, William E, Casey, Melissa, Nicol, Gordon R

“…In-source direct pyrolysis mass spectrometry is studied for rapid identification of polymers in industrial products. In this technique, polymers are pyrolyzed…”
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Catalytic Significance of the Specificity of Divalent Cations as KS and kcat Cofactors for Secreted Phospholipase A2 by YU, Bao-Zhu, ROGERS, Joseph, NICOL, Gordon R., THEOPOLD, Klaus H., SESHADRI, K., VISHWESHWARA, S., JAIN, Mahendra Kumar

“…Calcium is required for the substrate binding and for the chemical step of the interfacial catalytic turnover cycle of pancreatic phospholipase A2 (PLA2), but…”
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Differences among techniques for high-abundant protein depletion: Exploring the Human Plasma Proteome: The HUPO Plasma Proteome Project (HPPP) by ZOLOTARJOVA, Nina, MARTOSELLA, James, NICOL, Gordon, BAILEY, Jerome, BOYES, Barry E, BARRETT, William C

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The Proton Affinity and Entropy of Protonation of Lysinamide. The Effects of Intramolecular Proton Solvation by Kinser, Robin D, Nicol, Gordon, Ridge, D. P

“…The equilibrium constants for the gas-phase proton transfer from protonated tri-n-propylamine to lysinamide at several temperatures have been measured using…”
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Tandem mass spectrometric study of 1,3,5-trinitrobenzene molecular ion: an unusual ortho effect involving a hydrogen atom from the aromatic ring by Shukla, Anil, Nicol, Gordon, Futrell, Jean

“…Unimolecular (metastable) and collision‐induced dissociation of 1,3,5‐trinitrobenzene molecular ion was studied using linked scans and mass‐analyzed ion…”
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Methyl cation affinities by McMahon, Terrance B., Heinis, Thomas, Nicol, Gordon, Hovey, Jamey K., Kebarle, Paul

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Catalytic Significance of the Specificity of Divalent Cations as K S and k c at Cofactors for Secreted Phospholipase A 2 by Yu, Bao-Zhu, Rogers, Joseph, Nicol, Gordon R., Theopold, Klaus H., Seshadri, K., Vishweshwara, S., Jain, Mahendra Kumar

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Hydrothermal reactions of 1-nitrobutane in high-temperature water by Iyer, Sadasivan D., Nicol, Gordon R., Klein, Michael T.

“…Development of a rational basis for the design of safe and reliable methods for the destruction of high-energy materials and explosives motivated the study of…”
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Ion-molecule reaction studies of: Methyl cation affinities and hydrogen bonding in protonated ions by Nicol, Gordon Robert

“…The extent of proton transfer from H$\sb3$O$\sp{+}$(H$\sb2$O)$\sb{\rm h}$ to compounds B was studied with a pulsed electron high pressure mass spectrometer…”
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Catalytic Significance of the Specificity of Divalent Cations as K S and k c at Cofactors for Secreted Phospholipase A2 by Yu, Bao-Zhu, Rogers, Joseph, Nicol, Gordon R, Theopold, Klaus H, Seshadri, K, Vishweshwara, S, Jain, Mahendra Kumar

“…Calcium is required for the substrate binding and for the chemical step of the interfacial catalytic turnover cycle of pancreatic phospholipase A2 (PLA2), but…”
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Enhanced affinity columns simplify proteins fractionation: columns enable reproducible chromatographic separation with high recovery of low-abundance plasma proteins by Barrett, William, Martosella, James, Zolotarjova, Nina, Yang, Liang-Sheng, Szafransld, Cory, Nicol, Gordon

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Enhanced Affinity Columns Simplify Protein Fractionation by Barrett, William, Martosella, James, Zolotarjova, Nina, Liang-Sheng, Yang

“…Limitations of current protein fractionation methods are driving the development of more effective separation techniques, especially for resolving complex…”
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