Search Results - "NICOL, A. J"

Clinical evaluation of autologous gamma delta T cell-based immunotherapy for metastatic solid tumours by Nicol, A J, Tokuyama, H, Mattarollo, S R, Hagi, T, Suzuki, K, Yokokawa, K, Nieda, M

“…Background: Adoptive transfer of ex vivo expanded autologous V γ 9V δ 2 T cells may be of therapeutic benefit for cancer because of their potent direct…”
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Resuscitation with hydroxyethyl starch improves renal function and lactate clearance in penetrating trauma in a randomized controlled study: the FIRST trial (Fluids in Resuscitation of Severe Trauma) by James, M.F.M., Michell, W.L., Joubert, I.A., Nicol, A.J., Navsaria, P.H., Gillespie, R.S.

“…The role of fluids in trauma resuscitation is controversial. We compared resuscitation with 0.9% saline vs hydroxyethyl starch, HES 130/0.4, in severe trauma…”
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Management of penetrating neck injuries by Van Waes, O. J., Cheriex, K. C. A. L., Navsaria, P. H., van Riet, P. A., Nicol, A. J., Vermeulen, J.

“…Background: Routine surgical exploration after penetrating neck injury (PNI) leads to a large number of negative neck explorations and potential iatrogenic…”
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Nonoperative management of penetrating kidney injuries: a prospective audit by Moolman, C, Navsaria, P H, Lazarus, J, Pontin, A, Nicol, A J

“…The role of nonoperative management for penetrating kidney injuries is unknown. Therefore, we review the management and outcome of penetrating kidney injuries…”
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Packing for Control of Hemorrhage in Major Liver Trauma by Nicol, A. J., Hommes, M., Primrose, R., Navsaria, P. H., Krige, J. E. J.

“…Background Packing for complex liver injuries has been associated with an increased risk of abdominal sepsis and bile leaks. The aim of the present study was…”
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Temporary closure of open abdominal wounds by the modified sandwich-vacuum pack technique by Navsaria, P. H., Bunting, M., Omoshoro-Jones, J., Nicol, A. J., Kahn, D.

“…Background: A 5‐year experience with the modified sandwich–vacuum pack technique, using an opened 3‐litre urological irrigation bag and continuous…”
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Posterior leukoencephalopathy following intrathecal chemotherapy with MRA-documented vasospasm by HENDERSON, R. D, RAJAH, T, NICOL, A. J, READ, S. J

“…Posterior leukoencephalopathy syndromes have been reported with hypertension, and immunosuppressive and chemotherapy agents. Cerebral vasospasm on MR…”
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Small-molecule Bcl-2 inhibitors sensitise tumour cells to immune-mediated destruction by LICKLITER, J. D, COX, J, MCCARRON, J, MARTINEZ, N. R, SCHMIDT, C. W, LIN, H, NIEDA, M, NICOL, A. J

“…The cytotoxic effects of anticancer immune cells are mediated by perforin/granzyme-B, Fas ligand and tumour necrosis factor-related apoptosis-inducing ligand…”
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Selective non-operative management of liver gunshot injuries by Omoshoro-Jones, J. A. O., Nicol, A. J., Navsaria, P. H., Zellweger, R., Krige, J. E. J., Kahn, D. H.

“…Background: In contrast to non‐surgical treatment of blunt liver trauma, non‐operative management (NOM) of liver gunshot injuries (LGSIs) is not widely…”
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Endoscopic and operative treatment of delayed complications after pancreatic trauma: An analysis of 27 civilians treated in an academic Level 1 Trauma Centre by Krige, J.E.J, Kotze, U.K, Navsaria, P.H, Nicol, A.J

“…Abstract Background This study evaluated the efficacy of endoscopic treatment of delayed local complications including pseudocysts and persistent pancreatic…”
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The effect of lockdown on intentional and non- intentional injury during the COVID-19 pandemic in Cape Town, South Africa : a preliminary report by Navsaria, P.H, Nicol, A.J, Parry, C.D.H, Matzopoulos, R, Maqungo, S, Gaudin, R

“…Background. In response to the coronavirus pandemic, lockdown restrictions and a ban on alcohol sales were introduced in South Africa. Objectives. To…”
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The consequences of major visceral vascular injuries on outcome in patients with pancreatic injuries : a case-matched analysis by Kotze, U.K., Setshedi, M., Navsaria, P.H., Nicol, A.J., Krige, J.E.J., Jonas, E.G.

“…Background: Major pancreatic injuries are complex to treat, especially when combined with vascular and other critical organ injuries. This case-matched…”
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An analysis of predictors of morbidity after stab wounds of the pancreas in 78 consecutive injuries by Krige, J E J, Kotze, U K, Sayed, R, Navsaria, P H, Nicol, A J

“…Penetrating injuries of the pancreas may result in serious complications. This study assessed the factors influencing morbidity after stab wounds of the…”
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Diagnostic laparoscopy and diverting sigmoid loop colostomy in the management of civilian extraperitoneal rectal gunshot injuries by Navsaria, P. H., Shaw, J. M., Zellweger, R., Nicol, A. J., Kahn, D.

“…Background: This prospective study reviews the management of isolated civilian extraperitoneal rectal gunshot injuries using a protocol of diagnostic…”
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Penetrating Abdominal Vena Cava Injuries by Navsaria, P.H., de Bruyn, P., Nicol, A.J.

“…The surgical management and outcome of abdominal vena cava (AVC) injuries is presented. A retrospective record review of patients with AVC injuries treated in…”
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Factors affecting outcome in penetrating oesophageal trauma by Smakman, N., Nicol, A. J., Walther, G., Brooks, A., Navsaria, P. H., Zellweger, R.

“…Background: Penetrating oesophageal trauma is rare and the risk factors affecting outcome have not been clearly identified. Delayed management has been cited…”
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Dendritic cells cross‐talk with tumour antigen‐specific CD8+ T cells, Vγ9γδT cells and Vα24NKT cells in patients with glioblastoma multiforme and in healthy donors by Eiraku, Y., Terunuma, H., Yagi, M., Deng, X., Nicol, A. J., Nieda, M.

“…Summary The finding that dendritic cells (DCs) orchestrate innate and adaptive immune responses has stimulated research on harnessing DCs for developing more…”
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Effect of Dexamethasone and Fluticasone on Airway Hyperresponsiveness in Horses With Inflammatory Airway Disease by Léguillette, R., Tohver, T., Bond, S.L., Nicol, J.A., McDonald, K.J.

“…Background Airway hyperresponsiveness (AWHR), expressed as hypersensitivity (PC75RL) or hyperreactivity (slope of the histamine dose‐response curve), is a…”
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Subxiphoid pericardial window to exclude occult cardiac injury after penetrating thoracoabdominal trauma by Hommes, M., Nicol, A. J., van der Stok, J., Kodde, I., Navsaria, P. H.

“…Background An occult cardiac injury may be present in patients with an acute abdomen after penetrating thoracoabdominal trauma. This study assessed the use of…”
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Prognostic factors, morbidity and mortality in pancreatic trauma: A critical appraisal of 432 consecutive patients treated at a Level 1 Trauma Centre by Krige, J.E.J, Kotze, U.K, Setshedi, M, Nicol, A.J, Navsaria, P.H

“…Abstract Background This large retrospective observational cohort study evaluated prognostic factors, 30-day morbidity and mortality and complications related…”
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