Search Results - "NICKERSON, C. L"
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Utility of animal models for identification of potential therapeutics for rheumatoid arthritis
Published in Annals of the rheumatic diseases (01-11-2008)“…Animal models of rheumatoid arthritis (RA) are widely used for testing potential new therapies for RA. However, the question of which animal model is most…”
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Downstaging of colorectal cancer by the national bowel cancer screening programme in England: first round data from the first centre
Published in Colorectal disease (01-05-2010)“…Objective Data from randomized controlled trials of Colorectal Cancer (CRC) screening in Nottingham, UK and Funen, Denmark and pilot data from the English and…”
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Pulmonary antibacterial defenses during mild and severe influenza virus infection
Published in Infection and Immunity (01-09-1990)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Expression of HLA-B27 in transgenic mice is dependent on the mouse H-2D genes
Published in The Journal of experimental medicine (01-10-1990)“…HLA-B27 transgenic mice in the context of various H-2 haplotypes were produced. A high expression of the HLA-B27 antigen was observed in mice homozygous for…”
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Role of enterobacteria and HLA-B27 in spondyloarthropathies : studies with transgenic mice
Published in Annals of the rheumatic diseases (01-06-1990)“…Several MHC (major histocompatibility complex) genes are associated with increased incidence of disease. The strongest association is between the class I gene,…”
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Susceptibility of HLA-B27 transgenic mice to Yersinia enterocolitica infection
Published in Human immunology (01-08-1990)“…The majority of patients with reactive arthritis have the major histocompatibility complex class I gene HLA-B27. The development of arthritis in these patients…”
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The H-2D genes influence expression of HLA-B27 in transgenic mice
Published in Transplantation proceedings (01-02-1991)Get more information
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Effect of H-2 genes on expression of HLA-B27 and Yersinia-induced arthritis
Published in Scandinavian journal of rheumatology. Supplement (1990)“…HLA-B*2705 transgenic mice were continuously backcrossed to mice of the B10 background with various haplotypes. A high level of expression of the HLA-B27…”
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Expression of HLA-B27 in transgenic mice is controlled by gene(s) mapping between H-2D and H-2L loci
Published in Immunogenetics (New York) (01-02-1992)“…The level of HLA-B27 transgene expression on the cell surface is dependent on the host H-2 haplotype. Mice homozygous for the H-2b, H-2f, H-2s, H-2p, H-2r, and…”
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The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation
Published in Arthritis and rheumatism (01-03-1996)“…To assess the efficacy of leukotriene synthesis inhibitors, alone and in combination with a nonsteroidal antiinflammatory drug, as potential treatments for…”
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Expression of HLA-B27 in transgenic mice is controlled by the H-2D gene(s)
Published in International journal of cancer. Supplement (1991)“…The HLA-B27 transgene was introduced into mice of the B10 background with various H-2 haplotypes. High levels of B27 antigen were detected on the surface of…”
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ESR Studies of Transient Free Radicals in Irradiated Food Components
Published in IEEE transactions on nuclear science (01-02-1979)“…Electron spin resonance (ESR) detection techniques are applied to the study of free radicals produced in model systems representing food components irradiated…”
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13
mTOR — beyond transplantation
Published in Current opinion in pharmacology (01-08-2005)“…mTOR kinase plays a central role in the activation of many cell types, and blocking mTOR function with rapamycin results in arrest of the cell cycle at the G1…”
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Characterization of (2 R, 3 S)-2-({[4-(2-butynyloxy)phenyl]sulfonyl}amino)- N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-α converting enzyme
Published in International immunopharmacology (20-12-2004)“…TNF-α converting enzyme (TACE) is a validated therapeutic target for the development of oral tumor necrosis factor-α (TNF-α) inhibitors. Here we report the…”
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Regulation of inflammation by collagen-binding integrins alpha1beta1 and alpha2beta1 in models of hypersensitivity and arthritis
Published in The Journal of clinical investigation (01-03-2000)“…Adhesive interactions play an important role in inflammation by promoting leukocyte attachment and extravasation from the vasculature into the peripheral…”
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