Search Results - "NICHOLS, Joan"

Real-time imaging of dynamic tissues by Nichols, Joan E., Azar, Sasha R.

“…A combined modality enables real-time imaging of mouse lungs and spans whole-organ to cellular scales…”
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Implantable niche with local immunosuppression for islet allotransplantation achieves type 1 diabetes reversal in rats by Paez-Mayorga, Jesus, Campa-Carranza, Jocelyn Nikita, Capuani, Simone, Hernandez, Nathanael, Liu, Hsuan-Chen, Chua, Corrine Ying Xuan, Pons-Faudoa, Fernanda Paola, Malgir, Gulsah, Alvarez, Bella, Niles, Jean A., Argueta, Lissenya B., Shelton, Kathryn A., Kezar, Sarah, Nehete, Pramod N., Berman, Dora M., Willman, Melissa A., Li, Xian C., Ricordi, Camillo, Nichols, Joan E., Gaber, A. Osama, Kenyon, Norma S., Grattoni, Alessandro

“…Pancreatic islet transplantation efficacy for type 1 diabetes (T1D) management is limited by hypoxia-related graft attrition and need for systemic…”
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Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use by Nichols, Joan E, Niles, Jean A, Vega, Stephanie P, Argueta, Lissenya B, Eastaway, Adriene, Cortiella, Joaquin

“…Respiratory tract specific cell populations, or tissue engineered in vitro grown human lung, have the potential to be used as research tools to mimic…”
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Influence of acellular natural lung matrix on murine embryonic stem cell differentiation and tissue formation by Cortiella, Joaquin, Niles, Jean, Cantu, Andrea, Brettler, Andrea, Pham, Anthony, Vargas, Gracie, Winston, Sean, Wang, Jennifer, Walls, Shannon, Nichols, Joan E

“…We report here the first attempt to produce and use whole acellular (AC) lung as a matrix to support development of engineered lung tissue from murine…”
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Production and assessment of decellularized pig and human lung scaffolds by Nichols, Joan E, Niles, Jean, Riddle, Michael, Vargas, Gracie, Schilagard, Tuya, Ma, Liang, Edward, Kert, La Francesca, Saverio, Sakamoto, Jason, Vega, Stephanie, Ogadegbe, Marie, Mlcak, Ronald, Deyo, Donald, Woodson, Lee, McQuitty, Christopher, Lick, Scott, Beckles, Daniel, Melo, Esther, Cortiella, Joaquin

“…The authors have previously shown that acellular (AC) trachea-lung scaffolds can (1) be produced from natural rat lungs, (2) retain critical components of the…”
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Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation by Paez-Mayorga, Jesus, Capuani, Simone, Hernandez, Nathanael, Farina, Marco, Chua, Corrine Ying Xuan, Blanchard, Ryan, Sizovs, Antons, Liu, Hsuan-Chen, Fraga, Daniel W., Niles, Jean A., Salazar, Hector F., Corradetti, Bruna, Sikora, Andrew G., Kloc, Malgorzata, Li, Xian C., Gaber, A. Osama, Nichols, Joan E., Grattoni, Alessandro

“…Cell encapsulation is an attractive transplantation strategy to treat endocrine disorders. Transplanted cells offer a dynamic and stimulus-responsive system…”
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The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis by Nichols, Joan E., Niles, Jean A., Fleming, Elisa H., Roberts, Norbert J.

“…The immunopathological mechanisms as well as the role played by influenza A virus infection of human leukocytes and induction of apoptosis have not been fully…”
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Changes in local tissue microenvironment in response to subcutaneous long-acting delivery of tenofovir alafenamide in rats and non-human primates by Pons-Faudoa, Fernanda P., Di Trani, Nicola, Capuani, Simone, Hernandez, Nathanael, Wood, Anthony M., Nehete, Bharti, Niles, Jean, Shelton, Kathryn A., Kezar, Sarah, Bushman, Lane R., Chua, Corrine Ying Xuan, Ittmann, Michael M., Anderson, Peter L., Nehete, Pramod N., Arduino, Roberto C., Nichols, Joan E., Grattoni, Alessandro

“…Several implantable long-acting (LA) delivery systems have been developed for sustained subcutaneous administration of tenofovir alafenamide (TAF), a potent…”
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Transcutaneously refillable, 3D-printed biopolymeric encapsulation system for the transplantation of endocrine cells by Farina, Marco, Chua, Corrine Ying Xuan, Ballerini, Andrea, Thekkedath, Usha, Alexander, Jenolyn F., Rhudy, Jessica R., Torchio, Gianluca, Fraga, Daniel, Pathak, Ravi R., Villanueva, Mariana, Shin, Crystal S., Niles, Jean A., Sesana, Raffaella, Demarchi, Danilo, Sikora, Andrew G., Acharya, Ghanashyam S., Gaber, A. Osama, Nichols, Joan E., Grattoni, Alessandro

“…Autologous cell transplantation holds enormous promise to restore organ and tissue functions in the treatment of various pathologies including endocrine,…”
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Production and utilization of acellular lung scaffolds in tissue engineering by Nichols, Joan E., Niles, Jean A., Cortiella, Joaquin

“…Pulmonary disease is a worldwide public health problem that reduces the quality of life and increases the need for hospital admissions as well as the risk for…”
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Long-acting refillable nanofluidic implant confers protection against SHIV infection in nonhuman primates by Pons-Faudoa, Fernanda P, Di Trani, Nicola, Capuani, Simone, Campa-Carranza, Jocelyn Nikita, Nehete, Bharti, Sharma, Suman, Shelton, Kathryn A, Bushman, Lane R, Abdelmawla, Farah, Williams, Martin, Roon, Laura, Nerguizian, David, Chua, Corrine Ying Xuan, Ittmann, Michael M, Nichols, Joan E, Kimata, Jason T, Anderson, Peter L, Nehete, Pramod N, Arduino, Roberto C, Grattoni, Alessandro

“…The impact of pre-exposure prophylaxis (PrEP) on slowing the global HIV epidemic hinges on effective drugs and delivery platforms. Oral drug regimens are the…”
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HLA-associated protection of lymphocytes during influenza virus infection by Ochoa, Eliana E, Huda, Ruksana, Scheibel, Steven F, Nichols, Joan E, Mock, David J, El-Daher, Nayef, Domurat, Frank M, Roberts, Norbert J

“…Heterozygosity at HLA class I loci is generally considered beneficial for host defense. We report here an element of HLA class I homozygosity that may or may…”
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Platforms to test the temporospatial capabilities of carrier systems in delivering growth factors to benefit vascular bioengineering by Argueta, Lissenya B., Niles, Jean A., Sakamoto, Jason, Liu, Xuewu, Vega, Stephanie P., Frank, Luba, Paessler, Marco, Cortiella, Joaquin, Nichols, Joan E.

“…In this study we produced a set of in vitro culture platforms to model vascular cell responses to growth factors and factor delivery vehicles. Two of the…”
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Human Alveolar Macrophages May Not Be Susceptible to Direct Infection by a Human Influenza Virus by Ettensohn, David B., Frampton, Mark W., Nichols, Joan E., Roberts, Norbert J.

“…The current studies were undertaken to determine the susceptibility of human alveolar macrophages (AMs) to influenza A virus (IAV) infection in comparison with…”
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Human Primary Intestinal Epithelial Cells as an Improved In Vitro Model for Cryptosporidium parvum Infection by Castellanos-Gonzalez, Alejandro, Cabada, Miguel M, Nichols, Joan, Gomez, Guillermo, White, Jr, A Clinton

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Antiviral activities of ISG20 in positive-strand RNA virus infections by Zhou, Zhi, Wang, Nan, Woodson, Sara E, Dong, Qingming, Wang, Jie, Liang, Yuqiong, Rijnbrand, Rene, Wei, Lai, Nichols, Joan E, Guo, Ju-Tao, Holbrook, Michael R, Lemon, Stanley M, Li, Kui

“…Abstract ISG20 is an interferon-inducible 3′–5′ exonuclease that inhibits replication of several human and animal RNA viruses. However, the specificities of…”
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Influenza Virus Infection of Human Lymphocytes Occurs in the Immune Cell Cluster of the Developing Antiviral Response by Mock, David J, Frampton, Mark W, Nichols, Joan E, Domurat, Frank M, Signs, Denise J, Roberts, Jr, Norbert J

“…Monocytes-macrophages and lymphocytes are recruited to the respiratory tract in response to influenza virus challenge and are exposed to the virus during the…”
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Novel in vitro respiratory models to study lung development, physiology, pathology and toxicology by Nichols, Joan E, Niles, Jean A, Vega, Stephanie P, Cortiella, Joaquin

“…Detailed studies of lung pathology in patients during the course of development of acute lung injury or respiratory distress are limited, and in the past…”
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Reduced activation and proliferation of human lymphocytes exposed to respiratory syncytial virus compared to cells exposed to influenza virus by Fleming, Elisa H., Ochoa, Eliana E., Nichols, Joan E., O'Banion, M. Kerry, Salkind, Alan R., Roberts, Norbert J.

“…Both respiratory syncytial virus (RSV) and influenza A virus (IAV) may infect human peripheral blood mononuclear leukocytes (PBMC) during the immune response…”
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Enhanced In Vivo Vascularization of 3D‐Printed Cell Encapsulation Device Using Platelet‐Rich Plasma and Mesenchymal Stem Cells by Paez‐Mayorga, Jesus, Capuani, Simone, Farina, Marco, Lotito, Maria Luisa, Niles, Jean A., Salazar, Hector F., Rhudy, Jessica, Esnaola, Lucas, Chua, Corrine Ying Xuan, Taraballi, Francesca, Corradetti, Bruna, Shelton, Kathryn A., Nehete, Pramod N., Nichols, Joan E., Grattoni, Alessandro

“…The current standard for cell encapsulation platforms is enveloping cells in semipermeable membranes that physically isolate transplanted cells from the host…”
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