Search Results - "NICHOLLS, M."

The mechanism of action for hyaluronic acid treatment in the osteoarthritic knee: a systematic review by Altman, R D, Manjoo, A, Fierlinger, A, Niazi, F, Nicholls, M

“…Knee osteoarthritis (OA) is one of the leading causes of disability within the adult population. Current treatment options for OA of the knee include…”
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An investigation of how radiation may cause accelerated rates of tropical cyclogenesis and diurnal cycles of convective activity by Nicholls, M E

“…Recent cloud-resolving numerical modeling results suggest that radiative forcing causes accelerated rates of tropical cyclogenesis and early intensification…”
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SARS-CoV-2 Omicron variant replication in human bronchus and lung ex vivo by Hui, Kenrie P. Y., Ho, John C. W., Cheung, Man-chun, Ng, Ka-chun, Ching, Rachel H. H., Lai, Ka-ling, Kam, Tonia Tong, Gu, Haogao, Sit, Ko-Yung, Hsin, Michael K. Y., Au, Timmy W. K., Poon, Leo L. M., Peiris, Malik, Nicholls, John M., Chan, Michael C. W.

“…The emergence of SARS-CoV-2 variants of concern with progressively increased transmissibility between humans is a threat to global public health. The Omicron…”
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Pathogenesis and transmission of SARS-CoV-2 in golden hamsters by Sia, Sin Fun, Yan, Li-Meng, Chin, Alex W. H., Fung, Kevin, Choy, Ka-Tim, Wong, Alvina Y. L., Kaewpreedee, Prathanporn, Perera, Ranawaka A. P. M., Poon, Leo L. M., Nicholls, John M., Peiris, Malik, Yen, Hui-Ling

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus with high nucleotide identity to SARS-CoV and to SARS-related coronaviruses…”
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Further examination of the thermodynamic modification of the inflow layer of tropical cyclones by vertical wind shear by Riemer, M, Montgomery, M. T, Nicholls, M. E

“…Recent work has developed a new framework for the impact of vertical wind shear on the intensity evolution of tropical cyclones. A focus of this framework is…”
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Effect of B-type natriuretic peptide-guided treatment of chronic heart failure on total mortality and hospitalization: an individual patient meta-analysis by Troughton, Richard W, Frampton, Christopher M, Brunner-La Rocca, Hans-Peter, Pfisterer, Matthias, Eurlings, Luc W M, Erntell, Hans, Persson, Hans, O'Connor, Christopher M, Moertl, Deddo, Karlström, Patric, Dahlström, Ulf, Gaggin, Hanna K, Januzzi, James L, Berger, Rudolf, Richards, A Mark, Pinto, Yigal M, Nicholls, M Gary

“…Natriuretic peptide-guided (NP-guided) treatment of heart failure has been tested against standard clinically guided care in multiple studies, but findings…”
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Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures by Hui, Kenrie P Y, Cheung, Man-Chun, Perera, Ranawaka A P M, Ng, Ka-Chun, Bui, Christine H T, Ho, John C W, Ng, Mandy M T, Kuok, Denise I T, Shih, Kendrick C, Tsao, Sai-Wah, Poon, Leo L M, Peiris, Malik, Nicholls, John M, Chan, Michael C W

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019, causing a respiratory disease (coronavirus disease 2019, COVID-19) of…”
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A new paradigm for intensity modification of tropical cyclones: thermodynamic impact of vertical wind shear on the inflow layer by Riemer, M., Montgomery, M. T., Nicholls, M. E.

“…An important roadblock to improved intensity forecasts for tropical cyclones (TCs) is our incomplete understanding of the interaction of a TC with the…”
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Enantioselective Synthesis of [6]Carbohelicenes by González-Fernández, Elisa, Nicholls, Leo D. M, Schaaf, Lukas D, Farès, Christophe, Lehmann, Christian W, Alcarazo, Manuel

“…The use of α-cationic phosphonites derived from TADDOL as ancillary ligands has allowed a highly regio- and enantioselective synthesis of substituted…”
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Safety of short 3-hour recovery and same-day discharge following lower-limb angioplasty in outpatients with intermittent claudication and critical limb ischaemia by Almazedi, B., West, D., Nicholls, M., Bowker, A.

“…To investigate the safety and efficacy of short recovery day-case pathway following lower-limb angioplasty in both intermittent claudication and critical limb…”
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Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus–Associated Acute Lung Injury by Loy, Hayley, Kuok, Denise I T, Hui, Kenrie P Y, Choi, Miranda H L, Yuen, W, Nicholls, John M, Peiris, J S Malik, Chan, Michael C W

“…Human umbilical cord mesenchymal stromal cells are more effective than those derived from human bone marrow in alleviating mechanisms of acute lung injury…”
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The M, E, and N Structural Proteins of the Severe Acute Respiratory Syndrome Coronavirus Are Required for Efficient Assembly, Trafficking, and Release of Virus-Like Particles by SIU, Y. L, TEOH, K. T, BRUZZONE, R, NAL, B, LO, J, CHAN, C. M, KIEN, F, ESCRIOU, N, TSAO, S. W, NICHOLLS, J. M, ALTMEYER, R, PEIRIS, J. S. M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo by Chan, Michael C. W., Kuok, Denise I. T., Leung, Connie Y. H., Hui, Kenrie P. Y., Valkenburg, Sophie A., Lau, Eric H. Y., Nicholls, John M., Fang, Xiaohui, Guan, Yi, Lee, Jae W., Chan, Renee W. Y., Webster, Robert G., Matthay, Michael A., Peiris, J. S. Malik

“…Influenza can cause acute lung injury. Because immune responses often play a role, antivirals may not ensure a successful outcome. To identify pathogenic…”
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Viral subversion of selective autophagy is critical for biogenesis of virus replication organelles by Lan, Yun, van Leur, Sophie Wilhelmina, Fernando, Julia Ayano, Wong, Ho Him, Kampmann, Martin, Siu, Lewis, Zhang, Jingshu, Li, Mingyuan, Nicholls, John M., Sanyal, Sumana

“…Infection by many (+)RNA viruses is accompanied by ER-expansion and membrane remodelling to form viral replication organelles, followed by assembly and…”
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Enantioselective Synthesis of 1‐Aryl Benzo[5]helicenes Using BINOL‐Derived Cationic Phosphonites as Ancillary Ligands by Redero, Pablo, Hartung, Thierry, Zhang, Jianwei, Nicholls, Leo D. M., Zichen, Guo, Simon, Martin, Golz, Christopher, Alcarazo, Manuel

“…The synthesis of unprecedented BINOL‐derived cationic phosphonites is described. Through the use of these phosphanes as ancillary ligands in AuI catalysis, a…”
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Treatment of heart failure guided by plasma aminoterminal brain natriuretic peptide (N-BNP) concentrations by Troughton, Richard W, Frampton, Christopher M, Yandle, Timothy G, Espine, Eric A, Nicholls, M Gary, Richards, A Mark

“…There is currently no objective practical guide to intensity of drug treatment for individuals with heart failure. We hypothesised that pharmacotherapy guided…”
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Testing the activation–orientation account of spatial attentional asymmetries using transcranial direct current stimulation by Loftus, A.M., Nicholls, M.E.R.

“…The general population shows an attentional bias to the left, known as pseudoneglect. This bias is thought to be driven by higher levels of activation in right…”
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N-Terminal Pro–B-Type Natriuretic Peptide-Guided Treatment for Chronic Heart Failure by Lainchbury, John G., MD, Troughton, Richard W., MD, PhD, Strangman, Kim M., RN, Frampton, Christopher M., PhD, Pilbrow, Anna, PhD, Yandle, Timothy G., PhD, Hamid, Amjad K., MBChB, Nicholls, M. Gary, MD, Richards, A. Mark, MD, PhD

“…Objectives The purpose of this study was to compare the effects of N-terminal pro–B-type natriuretic peptide (NT-proBNP)-guided therapy with those of intensive…”
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Tropism, replication competence, and innate immune responses of influenza virus: an analysis of human airway organoids and ex-vivo bronchus cultures by Hui, Kenrie P Y, Ching, Rachel H H, Chan, Stan K H, Nicholls, John M, Sachs, Norman, Clevers, Hans, Peiris, J S Malik, Chan, Michael C W

“…Human airway organoids are three-dimensional cultures derived from stem cells, which self-organise in ex-vivo conditions to form so-called mini-airways. The…”
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Glycomic analysis of human respiratory tract tissues and correlation with influenza virus infection by Walther, Trevenan, Karamanska, Rositsa, Chan, Renee W Y, Chan, Michael C W, Jia, Nan, Air, Gillian, Hopton, Clark, Wong, Maria P, Dell, Anne, Malik Peiris, J S, Haslam, Stuart M, Nicholls, John M

“…The first step in influenza infection of the human respiratory tract is binding of the virus to sialic (Sia) acid terminated receptors. The binding of…”
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