Search Results - "NICHOL, Stuart T"

GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses by Lo, Michael K., Jordan, Robert, Arvey, Aaron, Sudhamsu, Jawahar, Shrivastava-Ranjan, Punya, Hotard, Anne L., Flint, Mike, McMullan, Laura K., Siegel, Dustin, Clarke, Michael O., Mackman, Richard L., Hui, Hon C., Perron, Michel, Ray, Adrian S., Cihlar, Tomas, Nichol, Stuart T., Spiropoulou, Christina F.

“…GS-5734 is a monophosphate prodrug of an adenosine nucleoside analog that showed therapeutic efficacy in a non-human primate model of Ebola virus infection. It…”
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Human Ebola virus infection results in substantial immune activation by McElroy, Anita K., Akondy, Rama S., Davis, Carl W., Ellebedy, Ali H., Mehta, Aneesh K., Kraft, Colleen S., Lyon, G. Marshall, Ribner, Bruce S., Varkey, Jay, Sidney, John, Sette, Alessandro, Campbell, Shelley, Ströher, Ute, Damon, Inger, Nichol, Stuart T., Spiropoulou, Christina F., Ahmed, Rafi

“…Significance In 2014, Ebola virus became a household term. The ongoing outbreak in West Africa is the largest Ebola virus outbreak ever recorded, with over…”
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Genetic detection and characterization of Lujo virus, a new hemorrhagic fever-associated arenavirus from southern Africa by Briese, Thomas, Paweska, Janusz T, McMullan, Laura K, Hutchison, Stephen K, Street, Craig, Palacios, Gustavo, Khristova, Marina L, Weyer, Jacqueline, Swanepoel, Robert, Egholm, Michael, Nichol, Stuart T, Lipkin, W Ian

“…Lujo virus (LUJV), a new member of the family Arenaviridae and the first hemorrhagic fever-associated arenavirus from the Old World discovered in three…”
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Transmission of Nipah Virus — 14 Years of Investigations in Bangladesh by Nikolay, Birgit, Salje, Henrik, Hossain, M. Jahangir, Khan, A.K.M. Dawlat, Sazzad, Hossain M.S, Rahman, Mahmudur, Daszak, Peter, Ströher, Ute, Pulliam, Juliet R.C, Kilpatrick, A. Marm, Nichol, Stuart T, Klena, John D, Sultana, Sharmin, Afroj, Sayma, Luby, Stephen P, Cauchemez, Simon, Gurley, Emily S

“…Nipah virus is a highly virulent zoonotic pathogen. In this report from Bangladesh, which included 40% of the world’s known cases, the risk factors for…”
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Assessment of the Risk of Ebola Virus Transmission from Bodily Fluids and Fomites by Bausch, Daniel G., Towner, Jonathan S., Dowell, Scott F., Kaducu, Felix, Lukwiya, Matthew, Sanchez, Anthony, Nichol, Stuart T., Ksiazek, Thomas G., Rollin, Pierre E.

“…Although Ebola virus (EBOV) is transmitted by unprotected physical contact with infected persons, few data exist on which specific bodily fluids are infected…”
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Recovery of Recombinant Crimean Congo Hemorrhagic Fever Virus Reveals a Function for Non-structural Glycoproteins Cleavage by Furin by Bergeron, Éric, Zivcec, Marko, Chakrabarti, Ayan K, Nichol, Stuart T, Albariño, César G, Spiropoulou, Christina F

“…Crimean Congo hemorrhagic fever virus (CCHFV) is a negative-strand RNA virus of the family Bunyaviridae (genus: Nairovirus). In humans, CCHFV causes fever,…”
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Prevalence and risk factors of Rift Valley fever in humans and animals from Kabale district in Southwestern Uganda, 2016 by Nyakarahuka, Luke, de St Maurice, Annabelle, Purpura, Lawrence, Ervin, Elizabeth, Balinandi, Stephen, Tumusiime, Alex, Kyondo, Jackson, Mulei, Sophia, Tusiime, Patrick, Lutwama, Julius, Klena, John D, Brown, Shelley, Knust, Barbara, Rollin, Pierre E, Nichol, Stuart T, Shoemaker, Trevor R

“…Rift Valley fever (RVF) is a zoonotic disease caused by Rift Valley fever virus (RVFV) found in Africa and the Middle East. Outbreaks can cause extensive…”
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Impact of enhanced viral haemorrhagic fever surveillance on outbreak detection and response in Uganda by Shoemaker, Trevor R, Balinandi, Stephen, Tumusiime, Alex, Nyakarahuka, Luke, Lutwama, Julius, Mbidde, Edward, Kofman, Aaron, Klena, John D, Ströher, Ute, Rollin, Pierre E, Nichol, Stuart T

“…All viral haemorrhagic fever laboratory confirmatory testing is done at UVRI and results are available within 24-48 h after sample reception.Since 2010, the…”
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Marburg virus infection detected in a common African bat by Towner, Jonathan S, Pourrut, Xavier, Albariño, César G, Nkogue, Chimène Nze, Bird, Brian H, Grard, Gilda, Ksiazek, Thomas G, Gonzalez, Jean-Paul, Nichol, Stuart T, Leroy, Eric M

“…Marburg and Ebola viruses can cause large hemorrhagic fever (HF) outbreaks with high case fatality (80-90%) in human and great apes. Identification of the…”
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Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats by Schuh, Amy J., Amman, Brian R., Jones, Megan E. B., Sealy, Tara K., Uebelhoer, Luke S., Spengler, Jessica R., Martin, Brock E., Coleman-McCray, Jo Ann D., Nichol, Stuart T., Towner, Jonathan S.

“…The Egyptian rousette bat (ERB) is a natural reservoir host for Marburg virus (MARV); however, the mechanisms by which MARV is transmitted bat-to-bat and to…”
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Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations by Kuhn, Jens H., Becker, Stephan, Ebihara, Hideki, Geisbert, Thomas W., Johnson, Karl M., Kawaoka, Yoshihiro, Lipkin, W. Ian, Negredo, Ana I., Netesov, Sergey V., Nichol, Stuart T., Palacios, Gustavo, Peters, Clarence J., Tenorio, Antonio, Volchkov, Viktor E., Jahrling, Peter B.

“…The taxonomy of the family Filoviridae (marburgviruses and ebolaviruses) has changed several times since the discovery of its members, resulting in a plethora…”
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Egyptian rousette bats maintain long-term protective immunity against Marburg virus infection despite diminished antibody levels by Schuh, Amy J., Amman, Brian R., Sealy, Tara K., Spengler, Jessica R., Nichol, Stuart T., Towner, Jonathan S.

“…Although bats are natural reservoir hosts for numerous zoonotic viruses, little is known about the long-term dynamics of the host immune response following…”
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Large serological survey showing cocirculation of Ebola and Marburg viruses in Gabonese bat populations, and a high seroprevalence of both viruses in Rousettus aegyptiacus by Pourrut, Xavier, Souris, Marc, Towner, Jonathan S, Rollin, Pierre E, Nichol, Stuart T, Gonzalez, Jean-Paul, Leroy, Eric

“…Ebola and Marburg viruses cause highly lethal hemorrhagic fevers in humans. Recently, bats of multiple species have been identified as possible natural hosts…”
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Molecular Evolution of Viruses of the Family Filoviridae Based on 97 Whole-Genome Sequences by Carroll, Serena A, Towner, Jonathan S, Sealy, Tara K, McMullan, Laura K, Khristova, Marina L, Burt, Felicity J, Swanepoel, Robert, Rollin, Pierre E, Nichol, Stuart T

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification of 2′-deoxy-2′-fluorocytidine as a potent inhibitor of Crimean-Congo hemorrhagic fever virus replication using a recombinant fluorescent reporter virus by Welch, Stephen R., Scholte, Florine E.M., Flint, Mike, Chatterjee, Payel, Nichol, Stuart T., Bergeron, Éric, Spiropoulou, Christina F.

“…Crimean-Congo hemorrhagic fever virus (CCHFV), a tick-borne orthonairovirus, causes a severe hemorrhagic disease in humans (Crimean-Congo hemorrhagic fever,…”
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Statins Suppress Ebola Virus Infectivity by Interfering with Glycoprotein Processing by Shrivastava-Ranjan, Punya, Flint, Mike, Bergeron, Éric, McElroy, Anita K, Chatterjee, Payel, Albariño, César G, Nichol, Stuart T, Spiropoulou, Christina F

“…Ebola virus (EBOV) infection is a major public health concern due to high fatality rates and limited effective treatments. Statins, widely used…”
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Seroepidemiological investigation of Crimean Congo hemorrhagic fever virus in livestock in Uganda, 2017 by Nyakarahuka, Luke, Kyondo, Jackson, Telford, Carson, Whitesell, Amy, Tumusiime, Alex, Mulei, Sophia, Baluku, Jimmy, Cossaboom, Caitlin M, Cannon, Deborah L, Montgomery, Joel M, Lutwama, Julius J, Nichol, Stuart T, Balinandi, Stephen K, Klena, John D, Shoemaker, Trevor R

“…Crimean-Congo Hemorrhagic fever (CCHF) is an important zoonotic disease transmitted to humans both by tick vectors and contact with fluids from an infected…”
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Chloroquine is a potent inhibitor of SARS coronavirus infection and spread by Vincent, Martin J, Bergeron, Eric, Benjannet, Suzanne, Erickson, Bobbie R, Rollin, Pierre E, Ksiazek, Thomas G, Seidah, Nabil G, Nichol, Stuart T

“…Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is…”
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Biomarker correlates of survival in pediatric patients with Ebola virus disease by McElroy, Anita K, Erickson, Bobbie R, Flietstra, Timothy D, Rollin, Pierre E, Nichol, Stuart T, Towner, Jonathan S, Spiropoulou, Christina F

“…Outbreaks of Ebola virus disease (EVD) occur sporadically in Africa and are associated with high case-fatality rates. Historically, children have been less…”
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Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda by Towner, Jonathan S, Sealy, Tara K, Khristova, Marina L, Albariño, César G, Conlan, Sean, Reeder, Serena A, Quan, Phenix-Lan, Lipkin, W Ian, Downing, Robert, Tappero, Jordan W, Okware, Samuel, Lutwama, Julius, Bakamutumaho, Barnabas, Kayiwa, John, Comer, James A, Rollin, Pierre E, Ksiazek, Thomas G, Nichol, Stuart T

“…Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to…”
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