Search Results - "NGUYEN-HUU XUONG"

Elemental mapping of labelled biological specimens at intermediate energy loss in an energy‐filtered TEM acquired using a direct detection device by Ramachandra, Ranjan, Mackey, Mason R., Hu, Junru, Peltier, Steven T., Xuong, Nguyen‐Huu, Ellisman, Mark H., Adams, Stephen R.

“…The technique of colour EM that was recently developed enabled localisation of specific macromolecules/proteins of interest by the targeted deposition of…”
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Crystal Structure of a Complex Between the Catalytic and Regulatory (RI[alpha]) Subunits of PKA by Kim, Choel, Xuong, Nguyen-Huu, Taylor, Susan S

“…The 2.0-angstrom structure of the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) catalytic subunit bound to a deletion mutant of a…”
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Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy by Milazzo, Anna-Clare, Cheng, Anchi, Moeller, Arne, Lyumkis, Dmitry, Jacovetty, Erica, Polukas, James, Ellisman, Mark H., Xuong, Nguyen-Huu, Carragher, Bridget, Potter, Clinton S.

“…We report on initial results of using a new direct detection device (DDD) for single particle reconstruction of vitreous ice embedded specimens. Images were…”
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Crystal structure of a transition state mimic of the catalytic subunit of cAMP-dependent protein kinase by Taylor, Susan S, Madhusudan, Akamine, Pearl, Xuong, Nguyen-Huu

“…To understand the molecular mechanism underlying phosphoryl transfer of cAMP-dependent protein kinase, the structure of the catalytic subunit in complex with…”
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Characterization of a direct detection device imaging camera for transmission electron microscopy by Milazzo, Anna-Clare, Moldovan, Grigore, Lanman, Jason, Jin, Liang, Bouwer, James C., Klienfelder, Stuart, Peltier, Steven T., Ellisman, Mark H., Kirkland, Angus I., Xuong, Nguyen-Huu

“…The complete characterization of a novel direct detection device (DDD) camera for transmission electron microscopy is reported, for the first time at primary…”
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Modeling and Analysis of Charged-Particle CMOS Image Sensor Arrays by Shengdong Li, Matis, H.S., Nguyen-Huu Xuong, Kleinfelder, S.

“…Direct-detection CMOS image sensors optimized for charged-particle imaging applications, such as electron microscopy and particle physics, have been designed,…”
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Crystal structure of the E230Q mutant of cAMP‐dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N‐terminal A helix by Wu, Jian, Yang, Jie, Kannan, Natarajan, Madhusudan, Xuong, Nguyen‐Huu, Ten Eyck, Lynn F., Taylor, Susan S.

“…Glu230, one of the acidic residues that cluster around the active site of the catalytic subunit of cAMP‐dependent protein kinase, plays an important role in…”
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Crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MgATP and peptide inhibitor by JIANHUA ZHENG, KNIGHTON, D. R, TEN EYCK, L. F, KARLSSON, R, NGUYEN-HUU XUONG, TAYLOR, S. S, SOWADSKI, J. M

“…The structure of a ternary complex of the catalytic subunit of cAMP-dependent protein kinase, MgATP, and a 20-residue inhibitor peptide was determined at a…”
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Structure of a Peptide Inhibitor Bound to the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase by Knighton, Daniel R., Zheng, Jianhua, Lynn F. Ten Eyck, Xuong, Nguyen-Huu, Taylor, Susan S., Sowadski, Janusz M.

“…The structure of a 20-amino acid peptide inhibitor bound to the catalytic subunit of cyclic AMP-dependent protein kinase, and its interactions with the enzyme,…”
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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase by Knighton, Daniel R., Zheng, Jianhua, Lynn F. Ten Eyck, Ashford, Victor A., Xuong, Nguyen-Huu, Taylor, Susan S., Sowadski, Janusz M.

“…The crystal structure of the catalytic subunit of cyclic adenosine monophosphate--dependent protein kinase complexed with a 20-amino acid substrate analog…”
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A Dynamic Mechanism for AKAP Binding to RII Isoforms of cAMP-Dependent Protein Kinase by Kinderman, Francis S., Kim, Choel, von Daake, Sventja, Ma, Yuliang, Pham, Bao Q., Spraggon, Glen, Xuong, Nguyen-Huu, Jennings, Patricia A., Taylor, Susan S.

“…A kinase-anchoring proteins (AKAPs) target PKA to specific microdomains by using an amphipathic helix that docks to N-terminal dimerization and docking (D/D)…”
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A binary complex of the catalytic subunit of cAMP-dependent protein kinase and adenosine further defines conformational flexibility by Narayana, Narendra, Cox, Sarah, Xuong, Nguyen-huu, Eyck, Lynn F Ten, Taylor, Susan S

“…Background: cAMP-dependent protein kinase (cAPK), a ubiquitous protein in eukaryotic cells, is one of the simplest members of the protein kinase family. It was…”
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Crystal structures of the myristylated catalytic subunit of cAMP‐dependent protein kinase reveal open and closed conformations by Zheng, Jianhua, Knighton, Daniel R., Taylor, Susan S., Xuong, Nguyen‐Huu, Sowadski, Janusz M., Eyck, Lynn F. Ten

“…Three crystal structures, representing two distinct conformational states, of the mammalian catalytic subunit of cAMP‐dependent protein kinase were solved…”
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Crystal structure of the tenth type III cell adhesion module of human fibronectin by Dickinson, C D, Veerapandian, B, Dai, X P, Hamlin, R C, Xuong, N H, Ruoslahti, E, Ely, K R

“…The crystal structure of the cell adhesion module of fibronectin (FNIII10) has been determined at 1.8 A resolution. A recombinant fragment corresponding to the…”
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Crystal structure of an HIV-binding recombinant fragment of human CD4 by Ryu, Seong-Eon, Kwong, Peter D, Truneh, Alemseged, Porter, Terence G, Arthos, James, Rosenberg, Martin, Dai, Xiaoping, Xuong, Nguyen-huu, Axel, Richard, Sweet, Raymond W, Hendrickson, Wayne A

“…CD4 glycoprotein on the surface of T cells helps in the immune response and is the receptor for HIV infection. The structure of a soluble fragment of CD4…”
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The crystal structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum by Kim, Choel, Xuong, Nguyen-Huu, Edwards, Steven, Madhusudan, Yee, Muh-Ching, Spraggon, Glen, E. Mills, Stanley

“…The structure of anthranilate phosphoribosyltransferase from the enterobacterium Pectobacterium carotovorum has been solved at 2.4 Å in complex with Mn…”
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Crystal Structure of a cAMP-dependent Protein Kinase Mutant at 1.26 Å: New Insights into the Catalytic Mechanism by Yang, Jie, Ten Eyck, Lynn F., Xuong, Nguyen-Huu, Taylor, Susan S.

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A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site by Narayana, N, Matthews, D A, Howell, E E, Nguyen-huu, X

“…Bacteria expressing R67-plasmid encoded dihydrofolate reductase (R67 DHFR) exhibit high-level resistance to the antibiotic trimethoprim. Native R67 DHFR is a…”
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Applications of direct detection device in transmission electron microscopy by Jin, Liang, Milazzo, Anna-Clare, Kleinfelder, Stuart, Li, Shengdong, Leblanc, Philippe, Duttweiler, Fred, Bouwer, James C., Peltier, Steven T., Ellisman, Mark H., Xuong, Nguyen-Huu

“…A prototype direct detection device (DDD) camera system has shown great promise in improving both the spatial resolution and the signal to noise ratio for…”
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Improving signal to noise in labeled biological specimens using energy-filtered TEM of sections with a drift correction strategy and a direct detection device by Ramachandra, Ranjan, Bouwer, James C, Mackey, Mason R, Bushong, Eric, Peltier, Steven T, Xuong, Nguyen-Huu, Ellisman, Mark H

“…Energy filtered transmission electron microscopy techniques are regularly used to build elemental maps of spatially distributed nanoparticles in materials and…”
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