Search Results - "NGUYEN, Doan C"

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein by Zost, Seth J., Gilchuk, Pavlo, Chen, Rita E., Case, James Brett, Reidy, Joseph X., Trivette, Andrew, Nargi, Rachel S., Sutton, Rachel E., Suryadevara, Naveenchandra, Chen, Elaine C., Binshtein, Elad, Shrihari, Swathi, Ostrowski, Mario, Chu, Helen Y., Didier, Jonathan E., MacRenaris, Keith W., Jones, Taylor, Day, Samuel, Myers, Luke, Eun-Hyung Lee, F., Nguyen, Doan C., Sanz, Ignacio, Martinez, David R., Rothlauf, Paul W., Bloyet, Louis-Marie, Whelan, Sean P. J., Baric, Ralph S., Thackray, Larissa B., Diamond, Michael S., Carnahan, Robert H., Crowe, James E.

“…Antibodies are a principal determinant of immunity for most RNA viruses and have promise to reduce infection or disease during major epidemics. The novel…”
Get full text

Factors Affecting Early Antibody Secreting Cell Maturation Into Long-Lived Plasma Cells by Nguyen, Doan C, Joyner, Chester J, Sanz, Iñaki, Lee, F Eun-Hyung

“…Antibody secreting cells (ASCs) are terminally differentiated cells of the humoral immune response and must adapt morphologically, transcriptionally, and…”
Get full text

Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…Human antibody-secreting cells (ASC) in peripheral blood are found after vaccination or infection but rapidly apoptose unless they migrate to the bone marrow…”
Get full text

Majority of human circulating IgG plasmablasts stop blasting in a cell-free pro-survival culture by Nguyen, Doan C., Saney, Celia, Hentenaar, Ian T., Cabrera-Mora, Monica, Capric, Violeta, Woodruff, Matthew C., Andrews, Joel, Lonial, Sagar, Sanz, Ignacio, Lee, F. Eun-Hyung

“…Following infection or vaccination, early-minted antibody secreting cells (ASC) or plasmablasts appear in circulation transiently, and a small fraction…”
Get full text

Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses by Duan, Meixue, Nguyen, Doan C., Joyner, Chester J., Saney, Celia L., Tipton, Christopher M., Andrews, Joel, Lonial, Sagar, Kim, Caroline, Hentenaar, Ian, Kosters, Astrid, Ghosn, Eliver, Jackson, Annette, Knechtle, Stuart, Maruthamuthu, Stalinraja, Chandran, Sindhu, Martin, Tom, Rajalingam, Raja, Vincenti, Flavio, Breeden, Cynthia, Sanz, Ignacio, Gibson, Greg, Lee, F. Eun-Hyung

“…Human bone marrow (BM) plasma cells are heterogeneous, ranging from newly arrived antibody-secreting cells (ASCs) to long-lived plasma cells (LLPCs). We…”
Get full text

Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus by Chen, Weirong, Hong, So-Hee, Jenks, Scott A., Anam, Fabliha A., Tipton, Christopher M., Woodruff, Matthew C., Hom, Jennifer R., Cashman, Kevin S., Faliti, Caterina Elisa, Wang, Xiaoqian, Kyu, Shuya, Wei, Chungwen, Scharer, Christopher D., Mi, Tian, Hicks, Sakeenah, Hartson, Louise, Nguyen, Doan C., Khosroshahi, Arezou, Lee, Saeyun, Wang, Youliang, Bugrovsky, Regina, Ishii, Yusho, Lee, F. Eun-Hyung, Sanz, Ignacio

“…Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple autoantibody types, some of which are produced by long-lived plasma cells…”
Get full text

Seroprevalence of antibodies to avian influenza A (H5) and A (H9) viruses among market poultry workers, Hanoi, Vietnam, 2001 by Uyeki, Timothy M, Nguyen, Doan C, Rowe, Thomas, Lu, Xiuhua, Hu-Primmer, Jean, Huynh, Lien P, Hang, Nguyen L K, Katz, Jacqueline M

“…The frequency of avian influenza A virus infections among poultry workers is not well understood. A seroprevalence study of market poultry workers and persons…”
Get full text

Microscale Generation of Cardiospheres Promotes Robust Enrichment of Cardiomyocytes Derived from Human Pluripotent Stem Cells by Nguyen, Doan C., Hookway, Tracy A., Wu, Qingling, Jha, Rajneesh, Preininger, Marcela K., Chen, Xuemin, Easley, Charles A., Spearman, Paul, Deshpande, Shriprasad R., Maher, Kevin, Wagner, Mary B., McDevitt, Todd C., Xu, Chunhui

“…Cardiomyocytes derived from human pluripotent stem cells (hPSCs) are a promising cell source for regenerative medicine, disease modeling, and drug discovery,…”
Get full text

Protection of Mice and Poultry from Lethal H5N1 Avian Influenza Virus through Adenovirus-Based Immunization by WENTAO GAO, SOLOFF, Adam C, BARRATT-BOYES, Simon M, GAMBOTTO, Andrea, XIUHUA LU, MONTECALVO, Angela, NGUYEN, Doan C, MATSUOKA, Yumi, ROBBINS, Paul D, SWAYNE, David E, DONIS, Ruben O, KATZ, Jacqueline M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…The original version of this Article omitted a declaration from the Competing Interests statement, which should have included the following: ‘A patent has been…”
Get full text

Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells by Nguyen, Doan C., Lewis, Holly C., Joyner, Chester, Warren, Vivien, Xiao, Haopeng, Kissick, Haydn T., Wu, Ronghu, Galipeau, Jacques, Lee, F. Eun-Hyung

“…Extracellular vesicles (EVs) from bone marrow (BM)-derived mesenchymal stromal cells (BM-MSC) are novel mechanisms of cell-cell communication over short and…”
Get full text

Isolation and Characterization of Avian Influenza Viruses, Including Highly Pathogenic H5N1, from Poultry in Live Bird Markets in Hanoi, Vietnam, in 2001 by Nguyen, Doan C, Uyeki, Timothy M, Jadhao, Samadhan, Maines, Taronna, Shaw, Michael, Matsuoka, Yumiko, Smith, Catherine, Rowe, Thomas, Lu, Xiuhua, Hall, Henrietta, Xu, Xiyan, Balish, Amanda, Klimov, Alexander, Tumpey, Terrence M, Swayne, David E, Huynh, Lien P.T, Nghiem, Ha K, Nguyen, Hanh H.T, Hoang, Long T, Cox, Nancy J, Katz, Jacqueline M

“…Since 1997, outbreaks of highly pathogenic (HP) H5N1 and circulation of H9N2 viruses among domestic poultry in Asia have posed a threat to public health. To…”
Get full text

Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses by Lu, Xiuhua, Edwards, Lindsay E., Desheva, Julia A., Nguyen, Doan C., Rekstin, Andrey, Stephenson, Iain, Szretter, Kristy, Cox, Nancy J., Rudenko, Larisa G., Klimov, Alexander, Katz, Jacqueline M.

“…Because of the time required to identify and produce an antigenically well-matched pandemic vaccine, vaccines that offer broader cross-reactive immunity and…”
Get full text

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 by Woodruff, Matthew C., Ramonell, Richard P., Nguyen, Doan C., Cashman, Kevin S., Saini, Ankur Singh, Haddad, Natalie S., Ley, Ariel M., Kyu, Shuya, Howell, J. Christina, Ozturk, Tugba, Lee, Saeyun, Suryadevara, Naveenchandra, Case, James Brett, Bugrovsky, Regina, Chen, Weirong, Estrada, Jacob, Morrison-Porter, Andrea, Derrico, Andrew, Anam, Fabliha A., Sharma, Monika, Wu, Henry M., Le, Sang N., Jenks, Scott A., Tipton, Christopher M., Staitieh, Bashar, Daiss, John L., Ghosn, Eliver, Diamond, Michael S., Carnahan, Robert H., Crowe, James E., Hu, William T., Lee, F. Eun-Hyung, Sanz, Ignacio

“…A wide spectrum of clinical manifestations has become a hallmark of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic,…”
Get full text

Pendrin mediates uptake of perchlorate in a mammalian in vitro system by Attanasio, Roberta, Scinicariello, Franco, Blount, Benjamin C., Valentin-Blasini, Liza, Rogers, Kenneth A., Nguyen, Doan C., Murray, H. Edward

“…► This study was designed to determine whether or not pendrin is able to mediate perchlorate uptake. ► A mammalian in vitro system was generated and used to…”
Get full text

Plasma cell survival: The intrinsic drivers, migratory signals, and extrinsic regulators by Nguyen, Doan C., Duan, Meixue, Ali, Mohammad, Ley, Ariel, Sanz, Ignacio, Lee, F. Eun‐Hyung

“…Summary Antibody‐secreting cells (ASC) are the effectors of protective humoral immunity and the only cell type that produces antibodies or immunoglobulins in…”
Get full text

Dysregulated naive B cells and de novo autoreactivity in severe COVID-19 by Woodruff, Matthew C., Ramonell, Richard P., Haddad, Natalie S., Anam, Fabliha A., Rudolph, Mark E., Walker, Tiffany A., Truong, Alexander D., Dixit, Adviteeya N., Han, Jenny E., Cabrera-Mora, Monica, Runnstrom, Martin C., Bugrovsky, Regina, Hom, Jennifer, Connolly, Erin C., Albizua, Igor, Javia, Vidhi, Cashman, Kevin S., Nguyen, Doan C., Kyu, Shuya, Singh Saini, Ankur, Piazza, Michael, Tipton, Christopher M., Khosroshahi, Arezou, Gibson, Greg, Martin, Greg S., Maier, Cheryl L., Esper, Annette, Jenks, Scott A., Lee, F. Eun-Hyung, Sanz, Ignacio

“…Severe SARS-CoV-2 infection 1 has been associated with highly inflammatory immune activation since the earliest days of the COVID-19 pandemic 2 – 5 . More…”
Get full text

COVID‐19 and plasma cells: Is there long‐lived protection? by Nguyen, Doan C., Lamothe, Pedro A., Woodruff, Matthew C., Saini, Ankur S., Faliti, Caterina E., Sanz, Ignacio, Lee, Frances Eun‐Hyung

“…Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has resulted in over 450 million cases with more than 6 million deaths…”
Get full text

Epidemiology of influenza in Hanoi, Vietnam, from 2001 to 2003 by Nguyen, Hang L.K, Saito, Reiko, Ngiem, Ha K, Nishikawa, Makoto, Shobugawa, Yugo, Nguyen, Doan C, Hoang, Long T, Huynh, Lien P, Suzuki, Hiroshi

“…Summary Objective The aim of this study was to clarify the epidemiology of laboratory-confirmed influenza in Hanoi, Vietnam. Methods Influenza was detected by…”
Get full text

SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination by Nguyen, Doan C, Hentenaar, Ian T, Morrison-Porter, Andrea, Solano, David, Haddad, Natalie S, Castrillon, Carlos, Runnstrom, Martin C, Lamothe, Pedro A, Andrews, Joel, Roberts, Danielle, Lonial, Sagar, Sanz, Ignacio, Lee, F Eun-Hyung

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are effective at protecting from severe disease, but the protective antibodies wane…”
Get full text