Search Results - "NEYLAN, John F"

Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial by Schena, Francesco P, Pascoe, Michael D, Alberu, Josefina, del Carmen Rial, Maria, Oberbauer, Rainer, Brennan, Daniel C, Campistol, Josep M, Racusen, Lorraine, Polinsky, Martin S, Goldberg-Alberts, Robert, Li, Huihua, Scarola, Joseph, Neylan, John F

“…The efficacy and safety of converting maintenance renal transplant recipients from calcineurin inhibitors (CNIs) to sirolimus (SRL) was evaluated. Eight…”
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Safety and efficacy of ferric citrate in patients with nondialysis-dependent chronic kidney disease by Chertow, Glenn M, Block, Geoffrey A, Neylan, John F, Pergola, Pablo E, Uhlig, Katrin, Fishbane, Steven

“…Two randomized, placebo-controlled trials conducted in patients with nondialysis-dependent (NDD) chronic kidney disease (CKD), iron deficiency anemia, and…”
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Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function by Vincenti, Flavio, Kim, Jim, Gouveia, Deborah, Pelle, Gabrielle, Mayne, Tracy J., Neylan, John F.

“…One-third of kidney transplantation patients experience acute kidney injury (AKI) resulting in delayed graft function (DGF), associated with increased risk of…”
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Comparison of Sirolimus Plus Tacrolimus Versus Sirolimus Plus Cyclosporine in High-Risk Renal Allograft Recipients : Results From an Open-Label, Randomized Trial by GABER, A. Osama, KAHAN, Barry D, VAN BUREN, Charles, SCHUITNAN, Seth L, SCAROLA, Joseph, NEYLAN, John F

“…The efficacy and safety of sirolimus (SRL) plus tacrolimus (TAC) versus SRL plus cyclosporine (CsA) were compared in high-risk renal allograft recipients…”
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Effect of ferric citrate on serum phosphate and fibroblast growth factor 23 among patients with nondialysis-dependent chronic kidney disease: path analyses by Block, Geoffrey A, Pergola, Pablo E, Fishbane, Steven, Martins, Julian G, LeWinter, Robin D, Uhlig, Katrin, Neylan, John F, Chertow, Glenn M

“…Abstract Background Among patients with nondialysis-dependent chronic kidney disease (NDD-CKD) and iron-deficiency anemia (IDA), ferric citrate increases…”
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Usefulness of Oral Ferric Citrate in Patients With Iron-Deficiency Anemia and Chronic Kidney Disease With or Without Heart Failure by McCullough, Peter A., Uhlig, Katrin, Neylan, John F., Pergola, Pablo E., Fishbane, Steven

“…Patients with chronic inflammatory conditions including chronic kidney disease (CKD) and heart failure (HF) are undertreated with iron-deficiency anemia (IDA)…”
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Lower Malignancy Rates in Renal Allograft Recipients Converted to Sirolimus-Based, Calcineurin Inhibitor-Free Immunotherapy: 24-Month Results From the CONVERT Trial by ALBERU, Josefina, PASCOE, Michael D, CAMPISTOL, Josep M, SCHENA, Francesco P, DEL CARMEN RIAL, Maria, POLINSKY, Martin, NEYLAN, John F, KORTH-BRADLEY, Joan, GOLDBERG-ALBERTS, Robert, MALLER, Eric S

“…Long-term immunosuppression imposes increased malignancy risk in renal allograft recipients, significantly contributing to overall morbidity and mortality…”
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Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation by CAMPISTOL, Josep M, ERIS, Josette, KREIS, Henri, BURKE, James T, BRAULT, Yves, SCAROLA, Joseph A, NEYLAN, John F, OBERBAUER, Rainer, FRIEND, Peter, HUTCHISON, Brian, MORALES, José M, CLAESSON, Kerstin, STALLONE, Giovanni, RUSS, Graeme, ROSTAING, Lionel

“…Sirolimus (SRL) is a mammalian target of rapamycin inhibitor that, in contrast to cyclosporine (CsA), has been shown to inhibit rather than promote cancers in…”
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Hepatocyte Growth Factor Mimetic ANG-3777 for Cardiac Surgery–Associated Acute Kidney Injury by Ayad, Sabry, Neylan, John F., Mayne, Tracy J., Gouveia, Deborah, Swaminathan, Madhav

“…Nearly one-third of patients undergoing cardiac surgery involving cardiopulmonary bypass (CPB) experience cardiac surgery–associated (CSA) acute kidney injury…”
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Hemoglobin response to ferric citrate in patients with nondialysis‐dependent chronic kidney disease and iron deficiency anemia by Pergola, Pablo E., Fishbane, Steven, LeWinter, Robin D., Neylan, John F., Uhlig, Katrin, Block, Geoffrey A., Chertow, Glenn M.

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Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal by KREIS, Henri, OBERBAUER, Rainer, NEYLAN, John F, CAMPISTOL, Josep M, MATHEW, Timothy, DALOZE, Pierre, SCHENA, Francesco P, BURKE, James T, BRAULT, Yves, GIOUD-PAQUET, Martine, SCAROLA, Joseph A

“…Graft function at 6 or 12 mo is positively correlated with renal transplant survival. The 36-mo results of a study that tested whether withdrawing cyclosporine…”
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Sirolimus‐Based Therapy Following Early Cyclosporine Withdrawal Provides Significantly Improved Renal Histology and Function at 3 Years by Mota, Alfredo, Arias, Manuel, Taskinen, Eero I., Paavonen, Timo, Brault, Yves, Legendre, Christophe, Claesson, Kerstin, Castagneto, Marco, Campistol, Josep M., Hutchison, Brian, Burke, James T., Yilmaz, Sedar, Häyry, Pekka, Neylan, John F.

“…Graft function and histology are predictive of renal transplant survival. The Rapamune Maintenance Regimen study demonstrated that early cyclosporine (CsA)…”
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Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation by Oberbauer, Rainer, Segoloni, Giuseppe, Campistol, Josep M, Kreis, Henri, Mota, Alfredo, Lawen, Joseph, Russ, Graeme, Grinyó, Josep M, Stallone, Giovanni, Hartmann, Anders, Pinto, Jose R, Chapman, Jeremy, Burke, James T, Brault, Yves, Neylan, John F

“…We report the 48-month results of a trial testing whether withdrawal of cyclosporine (CsA) from a sirolimus (SRL)-CsA-steroid (ST) regimen would impact renal…”
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Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function by RUSS, Graeme, SEGOLONI, Giuseppe, SCHENA, Francesco P, LELONG, Magali, BURKE, James T, NEYLAN, John F, OBERBAUER, Rainer, LEGENDRE, Christophe, MOTA, Alfredo, ERIS, Josette, GRINYO, Josep M, FRIEND, Peter, LAWEN, Joseph, HARTMANN, Anders

“…It has become increasingly important to refine therapeutic strategies according to individual patient characteristics. We evaluated the long-term impact of…”
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The influence of duffy blood group on renal allograft outcome in African Americans by AKALIN, Enver, NEYLAN, John F

“…African American patients demonstrate higher rates of acute allograft rejection and lower kidney-graft survival compared with white patients. Duffy antigen…”
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Gene expression analysis in human renal allograft biopsy samples using high-density oligoarray technology by AKALIN, Enver, HENDRIX, Rose C, POLAVARAPU, Rathna Giri, PEARSON, Thomas C, NEYLAN, John F, LARSEN, Christian P, LAKKIS, Fadi G

“…High-density oligoarray technology is a novel method for screening the expression of thousands of genes in a small tissue sample. Oligoarray analysis of genes…”
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Payment for Immunosuppression After Organ Transplantation by Kasiske, Bertram L, Cohen, David, Lucey, Michael R, Neylan, John F, for the American Society of Transplantation

“…Dramatic improvements in organ transplantation have meant that a growing number of patients must take expensive immunosuppressive medications for the rest of…”
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Factors influencing glomerular filtration rate in renal transplantation after cyclosporine withdrawal using sirolimus-based therapy: a multivariate analysis of results at five years by Legendre, Christophe, Brault, Yves, Morales, José M., Oberbauer, Rainer, Altieri, Paolo, Riad, Hany, Mahony, John, Messina, Maria, Pussell, Bruce, Martínez, Javier G., Lelong, Magali, Burke, James T., Neylan, John F.

“…Changes in calculated glomerular filtration rate (GFR) from baseline to five yr were analyzed in relation to risk factors among renal transplant recipients. At…”
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Microchimerism and rejection in clinical transplantation by Elwood, E T, Larsen, C P, Maurer, D H, Routenberg, K L, Neylan, J F, Whelchel, J D, O'Brien, D P, Pearson, T C

“…Haemopoietic microchimerism has been identified in recipients of solid-organ transplants and is thought by some to be critical for the development and…”
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Accuracy and variability of equations to estimate glomerular filtration rates in renal transplant patients receiving sirolimus and/or calcineurin inhibitor immunosuppression by Burke, James T, Brault, Yves, Kahan, Barry D, Hricik, Donald E, Grinyó, Josep M, Chapman, Jeremy R, Polinsky, Martin, Neylan, John F

“…Measured glomerular filtration rates (mGFRs) were obtained by (99)mTc-DPTA, (125)I-iothalamate, iohexol, (51)Cr-EDTA, non-radiolabeled iothalamate, or inulin…”
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