Search Results - "NEWMAN, Stuart A"

Inherency of Form and Function in Animal Development and Evolution by Newman, Stuart A

“…I discuss recent work on the origins of morphology and cell-type diversification in Metazoa - collectively the animals - and propose a scenario for how these…”
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Physico-Genetic Determinants in the Evolution of Development by Newman, Stuart A.

“…Animal bodies and the embryos that generate them exhibit an assortment of stereotypie morphological motifs that first appeared more than half a billion years…”
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The origins of multicellular organisms by Niklas, Karl J., Newman, Stuart A.

“…SUMMARY Multicellularity has evolved in several eukaryotic lineages leading to plants, fungi, and animals. Theoretically, in each case, this involved (1)…”
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Corrigendum: Inherency of Form and Function in Animal Development and Evolution by Newman, Stuart A

“…[This corrects the article DOI: 10.3389/fphys.2019.00702.]…”
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Borreliella burgdorferi Antimicrobial-Tolerant Persistence in Lyme Disease and Posttreatment Lyme Disease Syndromes by Cabello, Felipe C, Embers, Monica E, Newman, Stuart A, Godfrey, Henry P

“…The annual incidence of Lyme disease, caused by tick-transmitted Borreliella burgdorferi, is estimated to be at least 476,000 cases in the United States and…”
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Dynamical patterning modules: a "pattern language" for development and evolution of multicellular form by Newman, Stuart A, Bhat, Ramray

“…This article considers the role played by a core set of "dynamical patterning modules" (DPMs) in the origination, development and evolution of complex…”
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Polarity, planes of cell division, and the evolution of plant multicellularity by Niklas, Karl J., Wayne, Randy, Benítez, Mariana, Newman, Stuart A.

“…Organisms as diverse as bacteria, fungi, plants, and animals manifest a property called “polarity.” The literature shows that polarity emerges as a consequence…”
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Reply to Luger, “Why Is It So Hard to Find Persistent Borreliella burgdorferi?” by Cabello, Felipe C., Embers, Monica E., Newman, Stuart A., Godfrey, Henry P.

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Dynamical Patterning Modules, Biogeneric Materials, and the Evolution of Multicellular Plants by Benítez, Mariana, Hernández-Hernández, Valeria, Newman, Stuart A, Niklas, Karl J

“…Comparative analyses of developmental processes across a broad spectrum of organisms are required to fully understand the mechanisms responsible for the major…”
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Bare bones pattern formation: a core regulatory network in varying geometries reproduces major features of vertebrate limb development and evolution by Zhu, Jianfeng, Zhang, Yong-Tao, Alber, Mark S, Newman, Stuart A

“…Major unresolved questions regarding vertebrate limb development concern how the numbers of skeletal elements along the proximodistal (P-D) and anteroposterior…”
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Interplay of mesoscale physics and agent-like behaviors in the parallel evolution of aggregative multicellularity by Arias Del Angel, Juan A, Nanjundiah, Vidyanand, Benítez, Mariana, Newman, Stuart A

“…Abstract Myxobacteria and dictyostelids are prokaryotic and eukaryotic multicellular lineages, respectively, that after nutrient depletion aggregate and…”
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Gene loss, thermogenesis, and the origin of birds by Newman, Stuart A., Mezentseva, Nadezhda V., Badyaev, Alexander V.

“…Compared to related taxa, birds have exceptionally enlarged and diversified skeletal muscles, features that are closely associated with skeletal…”
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Rethinking gene regulatory networks in light of alternative splicing, intrinsically disordered protein domains, and post-translational modifications by Niklas, Karl J, Bondos, Sarah E, Dunker, A Keith, Newman, Stuart A

“…Models for genetic regulation and cell fate specification characteristically assume that gene regulatory networks (GRNs) are essentially deterministic and…”
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Form, function, mind: What doesn't compute (and what might) by Newman, Stuart A.

“…The applicability of computational and dynamical systems models to organisms is scrutinized, using examples from developmental biology and cognition…”
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Inherency and agency in the origin and evolution of biological functions by Newman, Stuart A

“…Abstract Although discussed by 20th century philosophers in terms drawn from the sciences of non-living systems, in recent decades biological function has been…”
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Cell elongation is key to in silico replication of in vitro vasculogenesis and subsequent remodeling by Merks, Roeland M.H., Brodsky, Sergey V., Goligorksy, Michael S., Newman, Stuart A., Glazier, James A.

“…Vasculogenesis, the de novo growth of the primary vascular network from initially dispersed endothelial cells, is the first step in the development of the…”
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Cell differentiation: What have we learned in 50 years? by Newman, Stuart A.

“…•Cell differentiation has been modeled as dynamical or modular.•Current models draw on both approaches but neglect metazoan-specific gene…”
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The evolutionary origin of digit patterning by Stewart, Thomas A, Bhat, Ramray, Newman, Stuart A

“…The evolution of tetrapod limbs from paired fins has long been of interest to both evolutionary and developmental biologists. Several recent investigative…”
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Dynamical patterning modules: physico-genetic determinants of morphological development and evolution by Newman, Stuart A, Bhat, Ramray

“…The shapes and forms of multicellular organisms arise by the generation of new cell states and types and changes in the numbers and rearrangements of the…”
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Mechanisms of pattern formation in development and evolution by Salazar-Ciudad, Isaac, Jernvall, Jukka, Newman, Stuart A

“…We present a classification of developmental mechanisms that have been shown experimentally to generate pattern and form in metazoan organisms. We propose that…”
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