Search Results - "NEWLAND, Adrian"

Thrombosis in immune thrombocytopenia — current status and future perspectives by Swan, Dawn, Newland, Adrian, Rodegheiro, Francesco, Thachil, Jecko

“…Summary Immune thrombocytopenia (ITP) is an autoimmune disorder in which a combination of defective platelet production and enhanced clearance leads to…”
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Current Management of Primary Immune Thrombocytopenia by Provan, Drew, Newland, Adrian C.

“…Primary immune thrombocytopenia is an autoimmune disorder of unknown cause affecting both children and adults. The low peripheral blood platelet count is…”
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Fostamatinib: a review of its clinical efficacy and safety in the management of chronic adult immune thrombocytopenia by Newland, Adrian, McDonald, Vickie

“…Management of chronic immune thrombocytopenia (ITP) is going through a transition, with the main driving forces being a better understanding of the disease,…”
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Practical guidance for the management of adults with immune thrombocytopenia during the COVID‐19 pandemic by Pavord, Sue, Thachil, Jecko, Hunt, Beverley J., Murphy, Mike, Lowe, Gillian, Laffan, Mike, Makris, Mike, Newland, Adrian C., Provan, Drew, Grainger, John D., Hill, Quentin A.

“…Summary This document aims to provide practical guidance for the assessment and management of patients with thrombocytopenia, with a particular focus on immune…”
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Updated international consensus report on the investigation and management of primary immune thrombocytopenia by Provan, Drew, Arnold, Donald M., Bussel, James B., Chong, Beng H., Cooper, Nichola, Gernsheimer, Terry, Ghanima, Waleed, Godeau, Bertrand, González-López, Tomás José, Grainger, John, Hou, Ming, Kruse, Caroline, McDonald, Vickie, Michel, Marc, Newland, Adrian C., Pavord, Sue, Rodeghiero, Francesco, Scully, Marie, Tomiyama, Yoshiaki, Wong, Raymond S., Zaja, Francesco, Kuter, David J.

“…Over the last decade, there have been numerous developments and changes in treatment practices for the management of patients with immune thrombocytopenia…”
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Fatigue in immune thrombocytopenia by Hill, Quentin A., Newland, Adrian C.

“…Summary Fatigue is an important aspect of health‐related quality of life from the patient perspective and can have significant socio‐economic consequences. It…”
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International consensus report on the investigation and management of primary immune thrombocytopenia by Provan, Drew, Stasi, Roberto, Newland, Adrian C., Blanchette, Victor S., Bolton-Maggs, Paula, Bussel, James B., Chong, Beng H., Cines, Douglas B., Gernsheimer, Terry B., Godeau, Bertrand, Grainger, John, Greer, Ian, Hunt, Beverley J., Imbach, Paul A., Lyons, Gordon, McMillan, Robert, Rodeghiero, Francesco, Sanz, Miguel A., Tarantino, Michael, Watson, Shirley, Young, Joan, Kuter, David J.

“…Previously published guidelines for the diagnosis and management of primary immune thrombocytopenia (ITP) require updating largely due to the introduction of…”
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Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia by Newland, Adrian C., Sánchez‐González, Blanca, Rejtő, László, Egyed, Miklos, Romanyuk, Nataliya, Godar, Marie, Verschueren, Katrien, Gandini, Domenica, Ulrichts, Peter, Beauchamp, Jon, Dreier, Torsten, Ward, E. Sally, Michel, Marc, Liebman, Howard A., Haard, Hans, Leupin, Nicolas, Kuter, David J.

“…Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder, characterized by a low platelet count (<100 × 109/L) in the absence of other…”
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SARS-CoV-2 vaccination and ITP in patients with de novo or preexisting ITP by Lee, Eun-Ju, Beltrami-Moreira, Marina, Al-Samkari, Hanny, Cuker, Adam, DiRaimo, Jennifer, Gernsheimer, Terry, Kruse, Alexandra, Kessler, Craig, Kruse, Caroline, Leavitt, Andrew D., Lee, Alfred I., Liebman, Howard A., Newland, Adrian C., Ray, Ashley E., Tarantino, Michael D., Thachil, Jecko, Kuter, David J., Cines, Douglas B., Bussel, James B.

“…Cases of de novo immune thrombocytopenia (ITP), including a fatality, following SARS-CoV-2 vaccination in previously healthy recipients led to studying its…”
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ITP: a historical perspective by Stasi, Roberto, Newland, Adrian C.

“…Summary A clinical syndrome of bleeding and purpura consistent with a diagnosis of immune thrombocytopenia (ITP) was described by Werlhof long before platelets…”
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Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database by SARPATWARI, Ameet, BENNETT, Dimitri, LOGIE, John W, SHUKLA, Amit, BEACH, Kathleen J, NEWLAND, Adrian C, SANDERSON, Simon, PROVAN, Drew

“…The risk of thromboembolic events in adults with primary immune thrombocytopenia has been little investigated despite findings of increased susceptibility in…”
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Current Concepts in the Diagnosis and Management of Adult Primary Immune Thrombocytopenia: Our Personal View by González-López, Tomás José, Newland, Adrian, Provan, Drew

“…Primary immune thrombocytopenia (ITP) is an acquired blood disorder that causes a reduction in circulating platelets with the potential for bleeding. The…”
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Standardization of bleeding assessment in immune thrombocytopenia: report from the International Working Group by Rodeghiero, Francesco, Michel, Marc, Gernsheimer, Terry, Ruggeri, Marco, Blanchette, Victor, Bussel, James B., Cines, Douglas B., Cooper, Nichola, Godeau, Bertrand, Greinacher, Andreas, Imbach, Paul, Khellaf, Mehdi, Klaassen, Robert J., Kühne, Thomas, Liebman, Howard, Mazzucconi, Maria Gabriella, Newland, Adrian, Pabinger, Ingrid, Tosetto, Alberto, Stasi, Roberto

“…In a previous publication on new terminology, definitions, and outcome criteria for immune thrombocytopenia (ITP), the International Working Group (IWG) on ITP…”
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Efficacy of romiplostim in patients with chronic immune thrombocytopenic purpura: a double-blind randomised controlled trial by Kuter, David J, Prof, Bussel, James B, MD, Lyons, Roger M, MD, Pullarkat, Vinod, MD, Gernsheimer, Terry B, MD, Senecal, Francis M, MD, Aledort, Louis M, MD, George, James N, MD, Kessler, Craig M, MD, Sanz, Miguel A, MD, Liebman, Howard A, MD, Slovick, Frank T, MD, de Wolf, J Th M, MD, Bourgeois, Emmanuelle, MD, Guthrie, Troy H, MD, Newland, Adrian, MA, Wasser, Jeffrey S, MD, Hamburg, Solomon I, MD, Grande, Carlos, MD, Lefrère, François, MD, Lichtin, Alan Eli, MD, Tarantino, Michael D, MD, Terebelo, Howard R, DO, Viallard, Jean-François, MD, Cuevas, Francis J, MD, Go, Ronald S, MD, Henry, David H, MD, Redner, Robert L, MD, Rice, Lawrence, MD, Schipperus, Martin R, MD, Guo, D Matthew, PhD, Nichol, Janet L, MS

“…Summary Background Chronic immune thrombocytopenic purpura (ITP) is characterised by accelerated platelet destruction and decreased platelet production…”
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Fostamatinib for persistent/chronic adult immune thrombocytopenia by Newland, Adrian, Lee, Eun-Ju, McDonald, Vickie, Bussel, James B

“…Immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by phagocytosis and destruction of autoantibody-coated platelets via spleen…”
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Thrombopoietin Mimetic Agents in the Management of Immune Thrombocytopenic Purpura by Newland, Adrian

“…Thrombopoietin (TPO) is a potent endogenous cytokine and the principal regulator of platelet production. Advances in the understanding of the structure of TPO…”
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United Kingdom immune thrombocytopenia registry: retrospective evaluation of bone marrow fibrosis in adult patients with primary immune thrombocytopenia and correlation with clinical findings by Rizvi, Hasan, Butler, Tom, Calaminici, Mariarita, Doobaree, Indraraj U., Nandigam, Raghava C., Bennett, Dimitri, Provan, Drew, Newland, Adrian C.

“…Summary Fibrosis has been reported in some patients with immune thrombocytopenia (ITP) treated with thrombopoietin receptor agonists (TPO‐RA). However,…”
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Immune thrombocytopenia -- what are the new treatment options? by Hallam, Simon, Provan, Drew, Newland, Adrian C

“…Primary immune thrombocytopenia (ITP) is a minor disease for many patients; however, the natural history is variable and unpredictable. Many patients who are…”
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Autologous 111 In-labelled platelet sequestration studies in patients with primary immune thrombocytopenia (ITP) prior to splenectomy: a report from the United Kingdom ITP Registry by Sarpatwari, Ameet, Provan, Drew, Erqou, Sebhat, Sobnack, Ravin, David Tai, Foong Way, Newland, Adrian C

“…While splenectomy is an effective therapy for primary immune thrombocytopenia (ITP), possible complications and observed non-complete response (CR) in…”
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The Health Technology Assessment of companion diagnostics: experience of NICE by Byron, Sarah K, Crabb, Nick, George, Elisabeth, Marlow, Mirella, Newland, Adrian

“…Companion diagnostics are used to aid clinical decision making to identify patients who are most likely to respond to treatment. They are becoming increasingly…”
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