Search Results - "NEW, A"

Anticonvulsants in the treatment of low back pain and lumbar radicular pain: a systematic review and meta-analysis by Enke, Oliver, MBBS MSc, New, Charles H., MBBS, New, Heather A., MBBS MPH, Mathieson, Stephanie, PhD, Latimer, Jane, PhD, Maher, Christopher G., PhD, Lin, C.-W. Christine, PhD, McLachlan, Andrew J., PhD

“…ABSTRACT BACKGROUND The use of anticonvulsants (e.g., gabapentin, pregabalin) to treat low back pain has increased substantially in recent years despite…”
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Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma Multiforme by Tilak, Manali, Holborn, Jennifer, New, Laura A, Lalonde, Jasmin, Jones, Nina

“…Glioblastoma multiforme (GBM) is amongst the deadliest of human cancers, with a median survival rate of just over one year following diagnosis. Characterized…”
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Modifiable risk factors for bone health & fragility fractures by Wilson-Barnes, Saskia L., Lanham-New, Susan A., Lambert, Helen

“…Osteoporosis is an ageing disorder characterised by poor microstructural architecture of the bone and an increase in the risk of fragility fractures, which…”
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Gender differences and similarities in aggression, suicidal behaviour, and psychiatric comorbidity in borderline personality disorder by Sher, L, Rutter, S B, New, A S, Siever, L J, Hazlett, E A

“…We examined gender differences and similarities in aggression, impulsivity, suicidal behaviour, and psychiatric comorbidity in men and women with borderline…”
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Is a vitamin D fortification strategy needed? by Buttriss, J. L., Lanham‐New, S. A.

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U.K. HiGEM: The New U.K. High-Resolution Global Environment Model—Model Description and Basic Evaluation by Shaffrey, L. C., Stevens, I., Norton, W. A., Roberts, M. J., Vidale, P. L., Harle, J. D., Jrrar, A., Stevens, D. P., Woodage, M. J., Demory, M. E., Donners, J., Clark, D. B., Clayton, A., Cole, J. W., Wilson, S. S., Connolley, W. M., Davies, T. M., Iwi, A. M., Johns, T. C., King, J. C., New, A. L., Slingo, J. M., Slingo, A., Steenman-Clark, L., Martin, G. M.

“…This article describes the development and evaluation of the U.K.’s new High-Resolution Global Environmental Model (HiGEM), which is based on the latest…”
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Labrador Slope Water connects the subarctic with the Gulf Stream by New, A L, Smeed, D A, Czaja, A, Blaker, A T, Mecking, J V, Mathews, J P, Sanchez-Franks, A

“…Labrador Slope Water (LSLW) is a relatively fresh and cool water mass that originates from the Labrador Current in the subarctic and is known to occur in the…”
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Insights into Decadal North Atlantic Sea Surface Temperature and Ocean Heat Content Variability from an Eddy-Permitting Coupled Climate Model by Moat, B. I., Sinha, B., Josey, S. A., Robson, J., Ortega, P., Sévellec, F., Holliday, N. P., McCarthy, G. D., New, A. L., Hirschi, J. J.-M.

“…An ocean mixed layer heat budget methodology is used to investigate the physical processes determining subpolar North Atlantic (SPNA) sea surface temperature…”
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Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4 + T Cells in Type 1 Diabetes by Martins, Christina P, New, Lee A, O'Connor, Erin C, Previte, Dana M, Cargill, Kasey R, Tse, Isabelle L, Sims-Lucas, Sunder, Piganelli, Jon D

“…In Type 1 Diabetes (T1D), CD4 T cells initiate autoimmune attack of pancreatic islet β cells. Importantly, bioenergetic programs dictate T cell function, with…”
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Dietary protein and bone health across the life-course: an updated systematic review and meta-analysis over 40 years by Darling, A. L., Manders, R. J. F., Sahni, S., Zhu, K., Hewitt, C. E., Prince, R. L., Millward, D. J., Lanham-New, S. A.

“…We undertook a systematic review and meta-analysis of published papers assessing dietary protein and bone health. We found little benefit of increasing protein…”
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Vitamin D Deficiency and Effects of Vitamin D Supplementation on Disease Severity in Patients with Atopic Dermatitis: A Systematic Review and Meta-Analysis in Adults and Children by Hattangdi-Haridas, Sonal R, Lanham-New, Susan A, Wong, Wilfred Hing Sang, Ho, Marco Hok Kung, Darling, Andrea L

“…Research has investigated 25-hydroxyvitamin D (25(OH)D) levels in the Atopic Dermatitis (AD) population, as well as changes in AD severity after vitamin D…”
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Sunlight and dietary contributions to the seasonal vitamin D status of cohorts of healthy postmenopausal women living at northerly latitudes: a major cause for concern? by Macdonald, H. M., Mavroeidi, A., Fraser, W. D., Darling, A. L., Black, A. J., Aucott, L., O’Neill, F., Hart, K., Berry, J. L., Lanham-New, S. A., Reid, D. M.

“…Summary We assessed sunlight and dietary contributions to vitamin D status in British postmenopausal women. Our true longitudinal 25-hydroxyvitamin D (25(OH)D)…”
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Vitamin D: One hundred years on by Buttriss, Judith L., Lanham‐New, Susan A.

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Multivalent nephrin-Nck interactions define a threshold for clustering and tyrosine-dependent nephrin endocytosis by Martin, Claire E, New, Laura A, Phippen, Noah J, Keyvani Chahi, Ava, Mitro, Alexander E, Takano, Tomoko, Pawson, Tony, Blasutig, Ivan M, Jones, Nina

“…Assembly of signaling molecules into micrometer-sized clusters is driven by multivalent protein-protein interactions, such as those found within the…”
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Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture by New, Laura A, Martin, Claire E, Scott, Rizaldy P, Platt, Mathew J, Keyvani Chahi, Ava, Stringer, Colin D, Lu, Peihua, Samborska, Bozena, Eremina, Vera, Takano, Tomoko, Simpson, Jeremy A, Quaggin, Susan E, Jones, Nina

“…Podocytes are specialized epithelial cells of the kidney blood filtration barrier that contribute to permselectivity via a series of interdigitating actin-rich…”
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Effect of vitamin D status and vitamin D supplementation on immune function and prevention of acute respiratory tract infections in dark-skinned individuals: a systematic review and meta-analysis by Bournot, Abigail R, Darling, Andrea L, Givens, Ian D, Lovegrove, Julie A, Lanham-New, Susan A, Hart, Kathryn H

“…This systematic review and meta-analysis examined the evidence for a potential relationship between vitamin D status and vitamin D supplementation on immune…”
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Impact of high latitude, urban living and ethnicity on 25-hydroxyvitamin D status: A need for multidisciplinary action? by Mendes, Marcela M., Darling, Andrea L., Hart, Kathryn H., Morse, Stephen, Murphy, Richard J., Lanham-New, Susan A.

“…•High latitude and urban living impact on vitamin D status.•These impacts may exacerbate vitamin D deficiency in some ethnic groups.•A multidisciplinary…”
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Internal solitary waves in the Mozambique Channel: Observations and interpretation by da Silva, J. C. B., New, A. L., Magalhaes, J. M.

“…This paper presents new results showing that the Sofala shelf in the Mozambique Channel (20°S, 36°E) is a previously unknown “hot spot” for the generation of…”
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Implementation strategies for improving vitamin D status and increasing vitamin D intake in the UK: current controversies and future perspectives: proceedings of the 2nd Rank Prize Funds Forum on vitamin D by Buttriss, Judy L., Lanham-New, Susan A., Steenson, Simon, Levy, Louis, Swan, Gillian E., Darling, Andrea L., Cashman, Kevin D., Allen, Rachel E., Durrant, Louise R., Smith, Colin P., Magee, Pamela, Hill, Tom R., Uday, Suma, Kiely, Mairead, Delamare, Gael, Hoyland, Alexa E., Larsen, Lise, Street, Laura N., Mathers, John C., Prentice, Ann

“…A multi-disciplinary expert group met to discuss vitamin D deficiency in the UK and strategies for improving population intakes and status. Changes to UK…”
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Role of the Microbiome in Regulating Bone Metabolism and Susceptibility to Osteoporosis by Cronin, Owen, Lanham-New, Susan A., Corfe, Bernard M., Gregson, Celia L., Darling, Andrea L., Ahmadi, Kourosh R., Gibson, Philippa S., Tobias, Jon H., Ward, Kate A., Traka, Maria H., Rossi, Megan, Williams, Claire, Harvey, Nicholas C., Cooper, Cyrus, Whelan, Kevin, Uitterlinden, André G., O’Toole, Paul W., Ohlsson, Claes, Compston, Juliet E., Ralston, Stuart H.

“…The human microbiota functions at the interface between diet, medication-use, lifestyle, host immune development and health. It is therefore closely aligned…”
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