Search Results - "NEVE, R. L"

The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling by Cahill, M E, Walker, D M, Gancarz, A M, Wang, Z J, Lardner, C K, Bagot, R C, Neve, R L, Dietz, D M, Nestler, E J

“…The nucleus accumbens (NAc) is a primary brain reward region composed predominantly of medium spiny neurons (MSNs). In response to early withdrawal from…”
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Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease by Lim, M A, Selak, M A, Xiang, Z, Krainc, D, Neve, R L, Kraemer, B C, Watts, J L, Kalb, R G

“…A growing body of research indicates that amyotrophic lateral sclerosis (ALS) patients and mouse models of ALS exhibit metabolic dysfunction. A subpopulation…”
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Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving by Werner, C T, Mitra, S, Martin, J A, Stewart, A F, Lepack, A E, Ramakrishnan, A, Gobira, P H, Wang, Z-J, Neve, R L, Gancarz, A M, Shen, L, Maze, I, Dietz, D M

“…Neuroadaptations in the nucleus accumbens (NAc) underlie cue-induced cocaine craving that intensifies ("incubates") during abstinence and is believed to…”
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Regulation of Cocaine Reward by CREB by Carlezon, William A., Thome, Johannes, Olson, Valerie G., Lane-Ladd, Sarah B., Brodkin, Edward S., Hiroi, Noboru, Duman, Ronald S., Neve, Rachael L., Nestler, Eric J.

“…Cocaine regulates the transcription factor CREB (adenosine 3′,5′-monophosphate response element binding protein) in rat nucleus accumbens, a brain region that…”
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Alzheimer's disease: a re-examination of the amyloid hypothesis by Neve, Rachael L., Robakis, Nikolaos K.

“…Alzheimer's disease (AD) is a neurodegenerative disorder of the brain characterized by the presence of neuritic amyloid plaques and neurofibrillary tangles…”
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Overexpression of HuD Accelerates Neurite Outgrowth and Increases GAP-43 mRNA Expression in Cortical Neurons and Retinoic Acid-Induced Embryonic Stem Cells in Vitro by Anderson, K.D., Sengupta, J., Morin, M., Neve, R.L., Valenzuela, C.F., Perrone-Bizzozero, N.I.

“…The neuron-specific RNA-binding protein HuD binds to a U-rich regulatory element of the 3′ untranslated region (3′ UTR) of the GAP-43 mRNA and stabilizes the…”
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MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice by Mitchell, A C, Javidfar, B, Pothula, V, Ibi, D, Shen, E Y, Peter, C J, Bicks, L K, Fehr, T, Jiang, Y, Brennand, K J, Neve, R L, Gonzalez-Maeso, J, Akbarian, S

“…Large-scale consortia mapping the genomic risk architectures of schizophrenia provide vast amounts of molecular information, with largely unexplored…”
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Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus by Neve, R.L, Howe, J.R, Hong, S, Kalb, R.G

“…We developed and characterized a recombinant herpes simplex virus vector and used it to introduce the complementary DNA encoding glutamate receptor subunit 1…”
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Sensitization to Morphine Induced by Viral-Mediated Gene Transfer by Carlezon, William A., Boundy, Virginia A., Haile, Colin N., Lane, Sarah B., Kalb, Robert G., Neve, Rachael L., Nestler, Eric J.

“…Repeated administration of morphine sensitizes animals to the stimulant and rewarding properties of the drug. It also selectively increases expression of GluR1…”
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MEF2C, a MADS/MEF2-Family Transcription Factor Expressed in a Laminar Distribution in Cerebral Cortex by Leifer, Dana, Krainc, Dimitri, Yu, Yie-Teh, McDermott, John, Breitbart, Roger E., Heng, John, Neve, Rachael L., Kosofsky, Barry, Nadal-Ginard, Bernardo, Lipton, Stuart A.

“…We have cloned cDNA encoding a human transcription factor that belongs to the MEF2 (myocyte-specific enhancer-binding factor 2) subfamily of the MADS…”
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SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens by Kim, H.-D., Hesterman, J., Call, T., Magazu, S., Keeley, E., Armenta, K., Kronman, H., Neve, R. L., Nestler, E. J., Ferguson, D.

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Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping by Gessler, Manfred, Poustka, Annemarie, Cavenee, Webster, Neve, Rachael L, Orkin, Stuart H, Bruns, Gail A. P

“…Cytogenetic analysis has identified chromosome 11p13 as the smallest overlap region for deletions found in individuals with WAGR syndrome, which includes Wilms…”
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Distinct Sites of Opiate Reward and Aversion within the Midbrain Identified Using a Herpes Simplex Virus Vector Expressing GluR1 by Carlezon, William A., Jr, Haile, Colin N, Coppersmith, Robert, Hayashi, Yasunori, Malinow, Roberto, Neve, Rachael L, Nestler, Eric J

“…Repeated administration of morphine increases expression of GluR1 (an AMPA glutamate receptor subunit) in the ventral tegmental area (VTA) of the midbrain, an…”
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Pivotal role for aspartate-80 in the regulation of dopamine D2 receptor affinity for drugs and inhibition of adenylyl cyclase by Neve, K A, Cox, B A, Henningsen, R A, Spanoyannis, A, Neve, R L

“…An aspartate residue corresponding to aspartate-80 of dopamine D2 receptors is strictly conserved among receptors that couple to guanine nucleotide-binding…”
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FOXO3a Is Broadly Neuroprotective In Vitro and In Vivo against Insults Implicated in Motor Neuron Diseases by Mojsilovic-Petrovic, Jelena, Nedelsky, Natalia, Boccitto, Marco, Mano, Itzhak, Georgiades, Savvas N, Zhou, Weiguo, Liu, Yuhong, Neve, Rachael L, Taylor, J. Paul, Driscoll, Monica, Clardy, Jon, Merry, Diane, Kalb, Robert G

“…Aging is a risk factor for the development of adult-onset neurodegenerative diseases. Although some of the molecular pathways regulating longevity and stress…”
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Overexpression of HuD, but Not of Its Truncated Form HuD I+II, Promotes GAP‐43 Gene Expression and Neurite Outgrowth in PC12 Cells in the Absence of Nerve Growth Factor by Anderson, Kim D., Morin, Melissa A., Beckel‐Mitchener, Andrea, Mobarak, Charlotte D., Neve, Rachael L., Furneaux, Henry M., Burry, Richard, Perrone‐Bizzozero, Nora I.

“…: We have previously shown that the RNA‐binding protein HuD binds to a regulatory element in the growth‐associated protein (GAP)‐43 mRNA and that this…”
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Neurotoxicity of a Fragment of the Amyloid Precursor Associated with Alzheimer's Disease by Yankner, Bruce A., Dawes, Linda R., Fisher, Shannon, Villa-Komaroff, Lydia, Oster-Granite, Mary Lou, Neve, Rachael L.

“…Amyloid deposition in senile plaques and the cerebral vasculature is a marker of Alzheimer's disease. Whether amyloid itself contributes to the…”
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Nerve Growth Factor Increases mRNA Levels for the Prion Protein and the β -amyloid Protein Precursor in Developing Hamster Brain by Mobley, William C., Neve, Rachael L., Prusiner, Stanley B., McKinley, Michael P.

“…Deposition of amyloid filaments serves as a pathologic hallmark for some neurodegenerative disorders. The prion protein (PrP) is found in amyloid of animals…”
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Deposition of β/A4 Immunoreactivity and Neuronal Pathology in Transgenic Mice Expressing the Carboxyl-Terminal Fragment of the Alzheimer Amyloid Precursor in the Brain by Kammesheidt, Anja, Boyce, Frederick M., Spanoyannis, Athena F., Cummings, Brian J., Ortegon, Marta, Cotman, Carl, Vaught, Jeffry L., Neve, Rachael L.

“…The deposition of amyloid in senile plaques and along the walls of the cerebral vasculature is a characteristic feature of Alzheimer disease. The peptide…”
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Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: Comparing D2L and D2S by Neve, K.A, Ford, C.P, Buck, D.C, Grandy, D.K, Neve, R.L, Phillips, T.J

“…Highlights • We compare the function of splice variants of the dopamine D2 receptor D2s and D2L. • We used virus-mediated expression of the receptors in D2…”
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