Search Results - "NERY, José A. C"
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Low rate of relapse after twelve-dose multidrug therapy for hansen's disease: A 20-year cohort study in a brazilian reference center
Published in PLoS neglected tropical diseases (01-05-2021)“…The World Health Organization has raised concerns about the increasing number of Hansen disease (HD) relapses worldwide, especially in Brazil, India, and…”
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Quantitative polymerase chain reaction in paucibacillary leprosy diagnosis: A follow-up study
Published in PLoS neglected tropical diseases (01-03-2019)“…The diagnosis of paucibacillary (PB) leprosy cases remains a challenge because of the absence of a confirmatory laboratory method. While quantitative…”
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Involvement of TNF-Producing CD8 + Effector Memory T Cells with Immunopathogenesis of Erythema Nodosum Leprosum in Leprosy Patients
Published in The American journal of tropical medicine and hygiene (01-01-2019)“…Type 2 reaction (T2R) or (ENL), a sudden episode of acute inflammation predominantly affecting lepromatous leprosy patients (LL), characterized by a reduced…”
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A leprosy clinical severity scale for erythema nodosum leprosum: An international, multicentre validation study of the ENLIST ENL Severity Scale
Published in PLoS neglected tropical diseases (03-07-2017)“…We wished to validate our recently devised 16-item ENLIST ENL Severity Scale, a clinical tool for measuring the severity of the serious leprosy associated…”
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Evaluation of Real-Time and Conventional PCR Targeting Complex 85 Genes for Detection of Mycobacterium leprae DNA in Skin Biopsy Samples from Patients Diagnosed with Leprosy
Published in Journal of Clinical Microbiology (01-09-2006)“…In spite of the decrease in the number of registered leprosy patients, the number of new cases diagnosed each year (400,000) has remained essentially…”
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High Matrix Metalloproteinase Production Correlates with Immune Activation and Leukocyte Migration in Leprosy Reactional Lesions
Published in Infection and Immunity (01-03-2010)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
Published in Nature communications (24-01-2018)“…Leprosy is a chronic human disease caused by the yet-uncultured pathogen Mycobacterium leprae . Although readily curable with multidrug therapy (MDT), over…”
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Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study
Published in Journal of translational medicine (11-09-2015)“…Peripheral nerve injury and bone lesions, well known leprosy complications, lead to deformities and incapacities. The phosphate-regulating gene with homologies…”
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Quantitative PCR for leprosy diagnosis and monitoring in household contacts: A follow-up study, 2011–2018
Published in Scientific reports (13-11-2019)“…Household contacts (HHC) of leprosy patients exhibit high-risk of developing leprosy and contact tracing is helpful for early diagnosis. From 2011 to…”
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The Potential Role of Magnetic Resonance Imaging in Patients With Hansen’s Neuropathy of the Feet: A Preliminary Communication
Published in International journal of lower extremity wounds (01-09-2009)“…A magnetic resonance imaging (MRI) protocol was performed in leprosy patients with a neuropathic foot and superficial ulcers and/or localized cellulitis but no…”
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ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum
Published in PLoS neglected tropical diseases (01-09-2015)“…Erythema nodosum leprosum (ENL) is a severe multisystem immune mediated complication of borderline lepromatous leprosy and lepromatous leprosy. ENL is…”
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Expression of metalloproteinases (MMP-2, MMP-9, and TACE) and TNF-α in the nerves of leprosy patients
Published in Journal of the peripheral nervous system (01-09-2007)“…Matrix metalloproteinases (MMPs) and tumor necrosis factor alpha (TNF‐α) play important and related roles in the pathogenesis of nerve injury. MMP‐dependent…”
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Methotrexate and prednisolone study in erythema nodosum leprosum (MaPs in ENL) protocol: a double-blind randomised clinical trial
Published in BMJ open (17-11-2020)“…IntroductionErythema nodosum leprosum (ENL) is an immunological complication of leprosy. ENL results in morbidity and disability and if it is not treated can…”
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The development of a severity scale for Erythema Nodosum Leprosum – the ENLIST ENL severity scale
Published in Leprosy review (01-09-2016)“…Introduction: Erythema nodosum leprosum (ENL) is a severe, multi-system complication of leprosy which is difficult to manage. The evidence for effective…”
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Anti-Inflammatory Drugs Block Cytokine mRNA Accumulation in the Skin and Improve the Clinical Condition of Reactional Leprosy Patients
Published in Journal of investigative dermatology (01-12-2000)“…The aim of this study was to investigate in what ways in vivo anti-inflammatory treatment affects cytokine mRNA expression in situ in both erythema nodosum…”
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Acro-osteolysis prior to diagnosis of leprosy
Published in Leprosy review (01-09-2000)“…lysis (bone resorption) has been observed in a heterogeneous group of congenital and acquired bone disorders. Leprosy is the main cause of peripheral…”
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Tumor necrosis factor-α promoter polymorphism TNF2 is associated with a stronger delayed-type hypersensivity reaction in the skin of borderline tuberculoid leprosy patients
Published in Immunogenetics (New York) (27-02-2001)“…The Mitsuda test is a delayed-type hypersensitivity reaction against intradermically injected, heat-killed leprosy bacilli called lepromin. Inoculation of…”
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The Influence of Thalidomide on the Clinical and Immunologic Manifestation of Erythema Nodosum Leprosum
Published in The Journal of infectious diseases (01-08-1993)“…Immunologic and clinical manifestations of erythema nodosum leprosum (ENL) and their response to thalidomide therapy were evaluated. Circulating tumor necrosis…”
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ENLIST 1: An International Multi-centre Cross-sectional Study of the Clinical Features of Erythema Nodosum Leprosum: e0004065
Published in PLoS neglected tropical diseases (01-09-2015)“…Erythema nodosum leprosum (ENL) is a severe multisystem immune mediated complication of borderline lepromatous leprosy and lepromatous leprosy. ENL is…”
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Reactional states in multibacillary Hansen disease patients during multidrug therapy
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-11-1998)“…It is well known that reactions are commonplace occurrences during the course of leprosy disease. Stigmatization may even be attributable to reactions which…”
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