Search Results - "NEGROIU, G."

Internalization and intracellular trafficking of poly(propylene imine) glycodendrimers with maltose shell in melanoma cells by Filimon, A, Sima, L E, Appelhans, D, Voit, B, Negroiu, G

“…The diagnosis and treatment of malignant melanoma by means of the formulation of active principles with dendrimeric nanoparticles is an area of great current…”
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Specific biofunctional performances of the hydroxyapatite–sodium maleate copolymer hybrid coating nanostructures evaluated by in vitro studies by Sima, L. E., Filimon, A., Piticescu, R. M., Chitanu, G. C., Suflet, D. M., Miroiu, M., Socol, G., Mihailescu, I. N., Neamtu, J., Negroiu, G.

“…The nanohybrid structures consisting of hydroxyapatite (HA) and sodium maleate-vinyl acetate copolymer (MP) deposited by Matrix Assisted Pulsed Laser…”
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Biocompatible structures based on hybrid organic-inorganic nanocrystalline materials by Piticescu, R M, Popescu, L M, Giurginca, M, Chitanu, G C, Negroiu, G

“…Finding new biomaterials for regenerative medicine is a major challenge to researchers working in the fields of materials science and health. Some of the most…”
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Investigation of the intracellular transport of tyrosinase and tyrosinase related protein (TRP)-1. The effect of endoplasmic reticulum (ER)-glucosidases inhibition by Negroiu, G, Branza-Nichita, N, Costin, G E, Titu, H, Petrescu, A J, Dwek, R A, Petrescu, S M

“…Melanin biosynthesis is completely inhibited in the B16 melanoma cells following their incubation with inhibitors of the two ER glucosidases. This is primarily…”
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Antigen‐specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan‐induced arthritis by BRENNAN, F. R., MIKECZ, K., BUZÁS, E. I., RAGASA, D., CS‐SZABÓ, G., NEGROIU, G., GLANT, T. T.

“…SUMMARY Cartilage proteoglycan (aggrecan)‐induced polyarthritis in BALB/c mice is characterized by chronic inflammation and destruction of joint tissues…”
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Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells by Neeft, Maaike, Wieffer, Marnix, de Jong, Arjan S, Negroiu, Gabriela, Metz, Corina H G, van Loon, Alexander, Griffith, Janice, Krijgsveld, Jeroen, Wulffraat, Nico, Koch, Henriette, Heck, Albert J R, Brose, Nils, Kleijmeer, Monique, van der Sluijs, Peter

“…Griscelli syndrome type 2 (GS2) is a genetic disorder in which patients exhibit life-threatening defects of cytotoxic T lymphocytes (CTLs) whose lytic granules…”
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Presentation of cartilage proteoglycan to a T cell hybridoma derived from a mouse with proteoglycan‐induced arthritis by BRENNAN, F. R., NEGROIU, G., BUZÁS, E. I., FÜLÖP, C., HOLLÓ, K., MIKECZ, K., GLANT, T. T.

“…SUMMARY Immunization of BALB/c mice with human fetal cartilage proteoglycan (PG) produces progressive polyarthritis, and T ceils play key roles in the…”
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Suppression of autoimmune responses and inflammatory events by leflunomide in an animal model for rheumatoid arthritis by Glant, T. T., Mikecz, K., Brennan, F., Negroiu, G., Bartlett, R. R.

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Tyrosinase-related protein-2 and -1 are trafficked on distinct routes in B16 melanoma cells by Negroiu, Gabriela, Dwek, Raymond A., Petrescu, Stefana M.

“…Tyrosinase related protein (TRP)-1 and -2 regulate the main steps in melanin synthesis and are immune targets in skin cancer or autoimmune pigmentary…”
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Mutations at Critical N-Glycosylation Sites Reduce Tyrosinase Activity by Altering Folding and Quality Control by Branza-Nichita, Norica, Negroiu, Gabriela, Petrescu, Andrei J., Garman, Elspeth F., Platt, Fran M., Wormald, Mark R., Dwek, Raymond A., Petrescu, Stefana M.

“…Tyrosinase is a copper-containing enzyme that regulates melanin biosynthesis in mammals. Mutations at a singleN-glycosylation sequon of tyrosinase have been…”
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The Inhibition of Early N-Glycan Processing Targets TRP-2 to Degradation in B16 Melanoma Cells by Negroiu, Gabriela, Dwek, Raymond A., Petrescu, Stefana M.

“…Tyrosinase-related protein-2 (TRP-2) is a DOPAchrome tautomerase catalyzing a distal step in the melanin synthesis pathway. Similar to the other two…”
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Folding and Maturation of Tyrosinase-related Protein-1 Are Regulated by the Post-translational Formation of Disulfide Bonds and by N-Glycan Processing by Negroiu, Gabriela, Dwek, Raymond A., Petrescu, Stefana M.

“…In this study we have explored the endoplasmic reticulum associated events accompanying the maturation of the tyrosinase-related protein-1 (TRP-1) nascent…”
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Critical Roles of Glycosaminoglycan Side Chains of Cartilage Proteoglycan (Aggrecan) in Antigen Recognition and Presentation by Glant, Tibor T, Buzas, Edit I, Finnegan, Alison, Negroiu, Gabriela, Cs-Szabo, Gabriella, Mikecz, Katalin

“…Systemic immunization of BALB/c mice with proteoglycan (aggrecan) from fetal human cartilage induces progressive polyarthritis, an experimental disease similar…”
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Tyrosinase and Glycoprotein Folding:  Roles of Chaperones That Recognize Glycans by Petrescu, Stefana M, Branza-Nichita, Norica, Negroiu, Gabriela, Petrescu, Andrei J, Dwek, Raymond A

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Protein specific N-glycosylation of tyrosinase and tyrosinase-related protein-1 in B16 mouse melanoma cells by Negroiu, G, Branza-Nichita, N, Petrescu, A J, Dwek, R A, Petrescu, S M

“…Tyrosinase and tyrosinase-related protein-1 (TRP-1) are two melanogenic enzymes that regulate melanin biosynthesis. Both are glycoproteins and belong to the…”
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N-Glycosylation Processing and Glycoprotein Folding−Lessons from the Tyrosinase-Related Proteins by Branza-Nichita, Norica, Petrescu, Andrei J, Negroiu, Gabriela, Dwek, Raymond A, Petrescu, Stefana M

“…Results that have been obtained for tyrosinase and some tyrosinase-related proteins which provide insight into the role of endoplasmicreticulum chaperones in…”
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The action of the collagen-Fe2+ complex at tissular level by Mirancea, N, Mirancea, D, Caloianu-Iordăchel, M, Toader, G, Moldovan, L, Negroiu, G

“…The aim of this paper is to know the iron dynamics and action of the collagen-Fe2+ complex at tissular level. The results showed that the collagen-Fe2+ complex…”
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A proteoglycan (aggrecan)-specific T cell hybridoma induces arthritis in BALB/c mice by Buzas, EI, Brennan, FR, Mikecz, K, Garzo, M, Negroiu, G, Hollo, K, Cs-Szabo, G, Pintye, E, Glant, TT

“…Aggrecan, the high buoyant density cartilage proteoglycan (PG), has been shown to induce progressive polyarthritis and ankylosing spondylitis in genetically…”
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PP-04 Effect of lysosomotropic amines on trp-2 maturation in b16 melanoma cells by Negroiu, G., Petrescu, S. M.

“…Abstract only…”
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