Search Results - "NEGISHI, M"

Cross talk between neurometals and amyloidogenic proteins at the synapse and the pathogenesis of neurodegenerative diseases by Kawahara, M, Kato-Negishi, M, Tanaka, K

“…Increasing evidence suggests that disruption of metal homeostasis contributes to the pathogenesis of various neurodegenerative diseases, including Alzheimer's…”
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Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells by Sun, D, Layer, R, Mueller, A C, Cichewicz, M A, Negishi, M, Paschal, B M, Dutta, A

“…The androgen receptor (AR) stimulates and represses gene expression to promote the initiation and progression of prostate cancer. Here, we report that androgen…”
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Phenobarbital response elements of cytochrome P450 genes and nuclear receptors by Sueyoshi, T, Negishi, M

“…Phenobarbital (PB) response elements are composed of various nuclear receptor (NR)-binding sites. A 51-bp distal element PB-responsive enhancer module (PBREM)…”
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Resting functional connectivity between the hemispheres in childhood absence epilepsy by BAI, X, GUO, J, KILLORY, B, VESTAL, M, BERMAN, R, NEGISHI, M, DANIELSON, N, NOVOTNY, E. J, CONSTABLE, R. T, BLUMENFELD, H

“…The fundamental mechanisms by which childhood absence epilepsy (CAE) changes neural networks even between seizures remain poorly understood. During seizures,…”
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p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38 by Hori, Takeshi, Moore, Rick, Negishi, Masahiko

“…Nuclear receptor constitutive androstane receptor (CAR, NR1I3), which regulates hepatic drug and energy metabolisms as well as cell growth and death, is…”
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Plexins: axon guidance and signal transduction by Negishi, M, Oinuma, I, Katoh, H

“…Axon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as semaphorins, ephrins and…”
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Phenobarbital and Insulin Reciprocate Activation of the Nuclear Receptor Constitutive Androstane Receptor through the Insulin Receptor by Yasujima, Tomoya, Saito, Kosuke, Moore, Rick, Negishi, Masahiko

“…Phenobarbital (PB) antagonized insulin to inactivate the insulin receptor and attenuated the insulin receptor downstream protein kinase B (AKT)-forkhead box…”
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Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin by Tasaka, Gen-Ichi, Negishi, Manabu, Oinuma, Izumi

“…Semaphorins have been identified as repulsive guidance molecules in the developing nervous system. We recently reported that the semaphorin 4D (Sema4D)…”
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Bmi1 is essential for leukemic reprogramming of myeloid progenitor cells by Yuan, J, Takeuchi, M, Negishi, M, Oguro, H, Ichikawa, H, Iwama, A

“…The polycomb group (PcG) proteins, particularly Bmi1, have an essential role in maintaining the self-renewing capacity of leukemic stem cells (LSCs). Although…”
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Nuclear receptors CAR and PXR in the regulation of hepatic metabolism by Tien, E. S., Negishi, M.

“…The nuclear receptors CAR and PXR were first characterized as xenosensing transcription factors regulating the induction of phase I and II…”
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ATF6 Activated by Proteolysis Binds in the Presence of NF-Y (CBF) Directly to the cis-Acting Element Responsible for the Mammalian Unfolded Protein Response by Yoshida, Hiderou, Okada, Tetsuya, Haze, Kyosuke, Yanagi, Hideki, Yura, Takashi, Negishi, Manabu, Mori, Kazutoshi

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Serine 202 regulates the nuclear translocation of constitutive active/androstane receptor by Hosseinpour, F, Moore, R, Negishi, M, Sueyoshi, T

“…The constitutive active receptor (CAR) in mouse primary hepatocytes undergoes okadaic acid (OA)-sensitive nuclear translocation after activation by xenobiotics…”
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Rho Family GTPases as Key Regulators for Neuronal Network Formation by Negishi, Manabu, Katoh, Hironori

“…Rho family GTPases act as transducers of signals from extracellular stimuli to the cytoskeleton and gene expression. Their actions are temporal and spatial…”
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Prophylactic procedure for inguinal hernia after radical retropubic prostatectomy by Matsunaga, R., Negishi, M., Higashi, H., Shida, H., Akakura, K.

“…Purpose The incidence of inguinal hernias (IH) after radical retropubic prostatectomy (RRP) has been reported to range from 10 to 50 %, but no prophylaxis for…”
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Endoplasmic Reticulum Stress-Induced Formation of Transcription Factor Complex ERSF Including NF-Y (CBF) and Activating Transcription Factors 6α and 6β That Activates the Mammalian Unfolded Protein Response by Yoshida, Hiderou, Okada, Tetsuya, Haze, Kyosuke, Yanagi, Hideki, Yura, Takashi, Negishi, Manabu, Mori, Kazutoshi

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Downregulation of prostaglandin E receptor subtype EP3 during colon cancer development by Shoji, Y, Takahashi, M, Kitamura, T, Watanabe, K, Kawamori, T, Maruyama, T, Sugimoto, Y, Negishi, M, Narumiya, S, Sugimura, T, Wakabayashi, K

“…Background and aims: Involvement of prostaglandin E2 (PGE2) receptors EP1, EP2, and EP4 in the formation of aberrant crypt foci (ACF) and/or intestinal polyps…”
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The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis by Yamazaki, Yuichi, Kakizaki, Satoru, Horiguchi, Norio, Sohara, Naondo, Sato, Ken, Takagi, Hitoshi, Mori, Masatomo, Negishi, Masahiko

“…Background: Non-alcoholic fatty liver disease is a common liver injury, but the pathophysiological mechanisms leading to the development of non-alcoholic…”
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Identification of the G13 (cAMP-response-element-binding protein-related protein) gene product related to activating transcription factor 6 as a transcriptional activator of the mammalian unfolded protein response by Haze, K, Okada, T, Yoshida, H, Yanagi, H, Yura, T, Negishi, M, Mori, K

“…Eukaryotic cells control the levels of molecular chaperones and folding enzymes in the endoplasmic reticulum (ER) by a transcriptional induction process termed…”
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The Peptide Near the C Terminus Regulates Receptor CAR Nuclear Translocation Induced by Xenochemicals in Mouse Liver by Zelko, Igor, Sueyoshi, Tatsuya, Kawamoto, Takeshi, Moore, Rick, Negishi, Masahiko

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Efficacy of physical therapy for intractable cupulolithiasis in an experimental model by Otsuka, K, Suzuki, M, Negishi, M, Shimizu, S, Inagaki, T, Konomi, U, Kondo, T, Ogawa, Y

“…To investigate what kinds of stimuli are effective in detaching otoconia from the cupula in three experimental models of cupulolithiasis. Three experimental…”
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