Search Results - "NEEL, J V"

The "Thrifty Genotype" in 1998 by Neel, James V.

“…Neel compares and contrasts facts concerning the genetic bases for obesity, hypertension and type II diabetes or non-insulin-dependent diabetes mellitus…”
Get full text

Allelic disequilibrium and allele frequency distribution as a function of social and demographic history by THOMPSON, E. A, NEEL, J. V

“…Allelic disequilibrium between closely linked genes is a common observation in human populations and often gives rise to speculation concerning the role of…”
Get full text

Hypothesis: "Rogue Cell"-Type Chromosomal Damage in Lymphocytes is Associated with Infection with the JC Human Polyoma Virus and has Implications for Oncopenesis by Neel, J. V., Major, E. O., Awa, A. A., Glover, T., Burgess, A., Traub, R., Curfman, B., Satoh, C.

“…The hemagglutination inhibition antibody titers against the JC and BK polyoma viruses (JCV and BKV, respectively) are significantly elevated in individuals…”
Get full text

The costs of human inbreeding and their implications for variations at the DNA level by Bittles, Alan H, Neel, James V

“…An analysis of the world literature on the children of first cousin marriages reveals that the depression of survival in offspring followed from birth…”
Get full text

Mitochondrial DNA "Clock" for the Amerinds and Its Implications for Timing their Entry into North America by Torroni, Antonio, Neel, James V., Barrantes, Ramiro, Schurr, Theodore G., Wallace, Douglas C.

“…Students of the time of entry of the ancestors of the Amerinds into the New World are divided into two camps, one favoring an "early" entry [more than…”
Get full text

Endemic Human T Cell Lymphotropic Virus Type II Infection among Isolated Brazilian Amerindians by Maloney, Elizabeth M., Biggar, Robert J., Neel, James V., Taylor, Maria E., Hahn, Beatrice H., Shaw, George M., Blattner, William A.

“…Evidence for human T celllymphotropic viruses (HTLV) was sought in sera and cells collected from adults in 13 isolated South and Central American Indian…”
Get full text

Virologic and Genetic Studies Relate Amerind Origins to the Indigenous People of the Mongolia/Manchuria/Southeastern Siberia Region by Neel, James V., Biggar, Robert J., Sukernik, Rem I.

“…A commonly held theory is that the first wave of migrants into the New World was derivative from the ethnic groups then inhabiting eastern Siberia. However,…”
Get full text

The children of parents exposed to atomic bombs : estimates of the genetic doubling dose of radiation for humans by NEEL, J. V, SCHULL, W. J, AWA, A. A, SATOH, C, KATO, H, OTAKE, M, YOSHIMOTO, Y

“…The data collected in Hiroshima and Nagasaki during the past 40 years on the children of survivors of the atomic bombings and on the children of a suitable…”
Get full text

An Association, in Adult Japanese, between the Occurrence of Rogue Cells among Cultured Lymphocytes (JC Virus Activity) and the Frequency of “Simple” Chromosomal Damage among the Lymphocytes of Persons Exhibiting These Rogue Cells by Neel, James V.

“…Data from a previous study of the cytogenetic effects, in cultured lymphocytes, of exposure to the atomic bomb in Hiroshima have been reanalyzed to determine…”
Get full text

Population amalgamation and genetic variation: observations on artificially agglomerated tribal populations of central and South America by RANAJIT CHAKRABORTY, SMOUSE, P. E, NEEL, J. V

“…The interpretation of data on genetic variation with regard to the relative roles of different evolutionary factors that produce and maintain genetic variation…”
Get full text

The Yanomamo and the 1960s Measles Epidemic by Neel, James V., Hill, Kim, Katz, Samuel L., Mann, Charles C.

Get full text

High titers of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes by Lazutka, J.R., Neel, J.V., Major, E.O., Dedonyt≐, V., Mierauskin≐, J., Slapšyt≐, G., Kesminien≐, A.

“…Associations of antibody titers to the JC and BK human polyoma viruses and the frequency of chromosome aberrations (CA) in human peripheral blood lymphocytes…”
Get full text

Malignant tumors during the first 2 decades of life in the offspring of atomic bomb survivors by YOSHIMOTO, Y, NEEL, J. V, SCHULL, W. J, KATO, H, SODA, M, ETO, M, MABUCHI, K

“…The risk of cancer (incidence) prior to age 20 years has been determined for children born to atomic bomb survivors and to a suitable comparison group. Tumor…”
Get full text

A Methylated Human 9-kb Repetitive Sequence on Acrocentric Chromosomes is Homologous to a Subtelomeric Repeat in Chimpanzees by Thoraval, D., Asakawa, J., Kodaira, M., Chang, C., Radany, E., Kuick, R., Lamb, B., Richardson, B., Neel, J. V., Glover, T., Hanash, S.

“…We have implemented an approach for the detection of DNA alterations in cancer by means of computerized analysis of end-labeled genomic fragments, separated in…”
Get full text

Congenital Malformations, Stillbirths, and Early Mortality among the Children of Atomic Bomb Survivors: A Reanalysis by Otake, Masanori, Schull, William J., Neel, James V.

“…Of all the data sets pertinent to the estimation of the genetic risks to humans following exposure to ionizing radiation, potentially the most informative is…”
Get full text

The newly characterized colicin Y provides evidence of positive selection in pore-former colicin diversification by Riley, M. A, Cadavid, Luis, Collett, Marc S, Neely, Melody N, Adams, Mark D, Phillips, Cheryl M, Neel, James V, Friedman, David

“…Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06511, USA 1 The Institute for Genomic Research, 9712 Medical Center Dr.,…”
Get full text

Search for mutations altering protein charge and/or function in children of atomic bomb survivors: final report by NEEL, J. V, SATOH, C, GORIKI, K, ASAKAWA, J.-I, FUJITA, M, TAKAHASHI, N, KAGEOKA, T, HAZAMA, R

“…A sample of (1) children whose parents had been proximally exposed (i.e., less than 2,000 m from the hypocenter) at the time of the atomic bombings of…”
Get full text

Analysis of Human Peripheral Blood T Cells and Single-Cell-Derived T Cell Clones Uncovers Extensive Clonal CpG Island Methylation Heterogeneity throughout the Genome by Zhu, Xiaoxiang, Deng, Chun, Kuick, Rork, Yung, Raymond, Lamb, Barbara, Neel, James V., Richardson, Bruce, Hanash, Samir

“…Methylation of cytosine residues in CpG dinucleotides is generally associated with silencing of gene expression. DNA methylation, as a somatic event, has the…”
Get full text

New approaches to evaluating the genetic effects of the atomic bombs by Neel, J V

“…In the aftermath of the atomic bombings of Hiroshima and Nagasaki 50 years ago, one of the compelling biomedical questions that arose concerned the genetic…”
Get full text

Studies of the Inheritance of Human Ribosomal DNA Variants Detected in Two-Dimensional Separations of Genomic Restriction Fragments by Kuick, R, Asakawa, J. I, Neel, J. V, Kodaira, M, Satoh, C, Thoraval, D, Gonzalez, I. L, Hanash, S. M

“…We have investigated the variation in human ribosomal DNA repeat units as revealed in two-dimensional electrophoretic separates of genomic restriction…”
Get full text