Search Results - "NEAL, S"

Aplastic Anemia by Young, Neal S

“…Once a uniformly fatal disease, aplastic anemia is now curable with allogeneic transplantation in 80% of children and 40% of adults, and immunosuppression with…”
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Somatic Mutations in “Benign” Disease by Mustjoki, Satu, Young, Neal S

“…DNA mutations occur in nearly every tissue throughout the human life span and accumulate at various rates in different tissues according to intrinsic and…”
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VEXAS syndrome by Grayson, Peter C., Patel, Bhavisha A., Young, Neal S.

“…VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is a monogenic disease of adulthood caused by somatic mutations in UBA1 in…”
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How I treat acquired aplastic anemia by Scheinberg, Phillip, Young, Neal S.

“…Survival in severe aplastic anemia (SAA) has markedly improved in the past 4 decades because of advances in hematopoietic stem cell transplantation,…”
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Current concepts in the pathophysiology and treatment of aplastic anemia by Young, Neal S

“…Historically viewed in isolation as an odd, rare, and invariably fatal blood disease, aplastic anemia is now of substantial interest for its immune…”
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Human Parvoviruses by Qiu, Jianming, Söderlund-Venermo, Maria, Young, Neal S

“…Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large Parvoviridae family, are human pathogens responsible for a variety of diseases. For…”
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Comment Regarding “Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn’s Disease: A Pragmatic Randomized Trial” by LeLeiko, Neal S.

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Edge to Edge Mitral Valve Repair After Transcatheter Valve Implantation: Jumping the Gun or Doing What Needs to Be Done? by Kleiman, Neal S

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The Biology of Aging and Frailty by Fedarko, Neal S., PhD

“…In developing and validating the concept of frailty as a geriatric syndrome, it has been necessary to distinguish the clinical expression of frailty from…”
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Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses by Chiappinelli, Katherine B., Strissel, Pamela L., Desrichard, Alexis, Li, Huili, Henke, Christine, Akman, Benjamin, Hein, Alexander, Rote, Neal S., Cope, Leslie M., Snyder, Alexandra, Makarov, Vladimir, Buhu, Sadna, Slamon, Dennis J., Wolchok, Jedd D., Pardoll, Drew M., Beckmann, Matthias W., Zahnow, Cynthia A., Merghoub, Taha, Chan, Timothy A., Baylin, Stephen B., Strick, Reiner

“…We show that DNA methyltransferase inhibitors (DNMTis) upregulate immune signaling in cancer through the viral defense pathway. In ovarian cancer (OC), DNMTis…”
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Assuring Success?: Selecting Patients With Bicuspid Aortic Valves for TAVR by Kleiman, Neal S.

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Inflammation, Autoimmunity, Infection, and Stroke: Epidemiology and Lessons From Therapeutic Intervention by Parikh, Neal S., Merkler, Alexander E., Iadecola, Costantino

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Bone marrow failure and the telomeropathies by Townsley, Danielle M., Dumitriu, Bogdan, Young, Neal S.

“…Our understanding of the pathophysiology of aplastic anemia is undergoing significant revision, with implications for diagnosis and treatment. Constitutional…”
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Single-cell genomics in acquired bone marrow failure syndromes by Wu, Zhijie, Young, Neal S.

“…[Display omitted] Mechanistic studies of immune bone marrow failure are difficult because of the scarcity of residual cells, the involvement of multiple cell…”
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Mendelian randomization elucidates links between nonalcoholic fatty liver disease and stroke by Parikh, Neal S.

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Getting it Right: Aortic Valve Replacement and the SYNTAX Score by Kleiman, Neal S

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A new paradigm for pediatric behavioral health care by LeLeiko, Neal S., Antosy, Alexandra, Geller, Allison

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Clonality in context: hematopoietic clones in their marrow environment by Cooper, James N., Young, Neal S.

“…Clonal hematopoiesis occurs normally, especially with aging, and in the setting of disease, not only in myeloid cancers but in bone marrow failure as well. In…”
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Monster Under the Bed?: Coronary Access After TAVR by Kleiman, Neal S.

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Delayed Coronary Obstruction After TAVR: A Call for Vigilance by Kleiman, Neal S.

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