Search Results - "NDAO, Momar"
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Will Auranofin Become a Golden New Treatment Against COVID-19?
Published in Frontiers in immunology (22-09-2021)“…Auranofin is an FDA-approved disease-modifying anti-rheumatic drug that has been used for decades for treatment of rheumatoid arthritis. This gold(I) compound…”
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Promising Technologies in the Field of Helminth Vaccines
Published in Frontiers in immunology (19-08-2021)“…Helminths contribute a larger global burden of disease than both malaria and tuberculosis. These eukaryotes have caused human infections since before our…”
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Aptamer-Based Technologies for Parasite Detection
Published in Sensors (Basel, Switzerland) (01-01-2023)“…Centuries of scientific breakthroughs have brought us closer to understanding and managing the spread of parasitic diseases. Despite ongoing technological…”
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Cutaneous leishmaniasis in the 21st century: from the laboratory to the bedside
Published in Current opinion in infectious diseases (01-10-2019)“…PURPOSE OF REVIEWDespite modern advances in molecular diagnostic tools and a better understanding of its complex pathophysiology, cutaneous leishmaniasis, a…”
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Usefulness of polymerase chain reaction tests in Chagas disease studies
Published in Frontiers in parasitology (13-02-2024)“…The Polymerase Chain Reaction (PCR) test is a highly sensitive, specific, and rapid diagnostic tool for Chagas disease. Chagas disease is caused by the…”
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Cysteine proteases in protozoan parasites
Published in PLoS neglected tropical diseases (01-08-2018)“…Cysteine proteases (CPs) play key roles in the pathogenesis of protozoan parasites, including cell/tissue penetration, hydrolysis of host or parasite proteins,…”
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Multiplexed Real-Time PCR Assay for Discrimination of Plasmodium Species with Improved Sensitivity for Mixed Infections
Published in Journal of Clinical Microbiology (01-04-2009)“…The implementation of real-time PCR for the diagnosis of malaria has been hampered by poor sensitivity for the detection of mixed infections. We have optimized…”
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Laboratory Features of Trichinellosis and Eosinophilia Threshold for Testing, Nunavik, Quebec, Canada, 2009-2019
Published in Emerging infectious diseases (01-12-2022)“…Prolonged eosinophilia is characteristic of trichinellosis. To determine the optimal eosinophil threshold for reflex Trichinella testing, we examined all 43…”
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The Diverse Applications of Recombinant BCG-Based Vaccines to Target Infectious Diseases Other Than Tuberculosis: An Overview
Published in Frontiers in microbiology (21-10-2021)“…Live attenuated Bacillus Calmette-Guérin (BCG) is the world's most widely used vaccine which is mainly administered for its protection against tuberculosis…”
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Trypanosoma cruzi Infection and Host Lipid Metabolism
Published in Mediators of Inflammation (01-01-2014)“…Trypanosoma cruzi is the causative agent of Chagas disease. Approximately 8 million people are thought to be affected worldwide. Several players in host lipid…”
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Reversible Cysteine Protease Inhibitors Show Promise for a Chagas Disease Cure
Published in Antimicrobial Agents and Chemotherapy (01-02-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Recent Advances in the Development of Adenovirus-Vectored Vaccines for Parasitic Infections
Published in Pharmaceuticals (Basel, Switzerland) (22-02-2023)“…Vaccines against parasites have lagged centuries behind those against viral and bacterial infections, despite the devastating morbidity and widespread effects…”
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Characterization and Diagnostic Application of Trypanosoma cruzi Trypomastigote Excreted-Secreted Antigens Shed in Extracellular Vesicles Released from Infected Mammalian Cells
Published in Journal of clinical microbiology (01-03-2017)“…Chagas disease, caused by , although endemic in many parts of Central and South America, is emerging as a global health threat through the potential…”
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Serological and molecular detection of Toxoplasma gondii in terrestrial and marine wildlife harvested for food in Nunavik, Canada
Published in Parasites & vectors (03-04-2019)“…Toxoplasma gondii, a zoonotic protozoan parasite, infects mammals and birds worldwide. Infection in humans is often asymptomatic, though illnesses can occur in…”
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Vaccination against the digestive enzyme Cathepsin B using a YS1646 Salmonella enterica Typhimurium vector provides almost complete protection against Schistosoma mansoni challenge in a mouse model
Published in PLoS neglected tropical diseases (01-12-2019)“…Schistosoma mansoni threatens hundreds of millions of people in >50 countries. Schistosomulae migrate through the lung and adult worms reside in blood vessels…”
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The diagnosis of human fascioliasis by enzyme-linked immunosorbent assay (ELISA) using recombinant cathepsin L protease
Published in PLoS neglected tropical diseases (01-09-2013)“…Fascioliasis is a worldwide parasitic disease of domestic animals caused by helminths of the genus Fasciola. In many parts of the world, particularly in poor…”
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Adjuvanted Schistosoma mansoni -Cathepsin B With Sulfated Lactosyl Archaeol Archaeosomes or AddaVax™ Provides Protection in a Pre-Clinical Schistosomiasis Model
Published in Frontiers in immunology (16-11-2020)“…Schistosomiasis threatens 800 million people worldwide. Chronic pathology manifests as hepatosplenomegaly, and intestinal schistosomiasis caused by can lead to…”
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Canadian contributions to research on neglected tropical diseases
Published in PLoS neglected tropical diseases (01-07-2021)“…Background The World Health Organization's (WHO) Neglected Tropical Disease (NTD) Road Map for 2021-2030 was recently endorsed by all member states at the…”
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Identification of Candidate Serum Biomarkers for Schistosoma mansoni Infected Mice Using Multiple Proteomic Platforms
Published in PloS one (03-05-2016)“…Schistosomiasis is an important helminth infection of humans. There are few reliable diagnostic biomarkers for early infection, for recurrent infection or to…”
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