Search Results - "NAYLOR, Tara L"

MicroRNAs Exhibit High Frequency Genomic Alterations in Human Cancer by Zhang, Lin, Huang, Jia, Yang, Nuo, Greshock, Joel, Megraw, Molly S., Giannakakis, Antonis, Liang, Shun, Naylor, Tara L., Barchetti, Andrea, Ward, Michelle R., Yao, George, Medina, Angelica, O'Brien-Jenkins, Ann, Katsaros, Dionyssios, Hatzigeorgiou, Artemis, Gimotty, Phyllis A., Weber, Barbara L., Coukos, George

“…MicroRNAs (miRNAs) are endogenous noncoding RNAs, which negatively regulate gene expression. To determine genomewide miRNA DNA copy number abnormalities in…”
Get full text

Protein Kinase C Inhibitor Sotrastaurin Selectively Inhibits the Growth of CD79 Mutant Diffuse Large B-Cell Lymphomas by NAYLOR, Tara L, HUAPING TANG, YAO, Yung-Mae, WARMUTH, Markus, LENZ, Georg, STEGMEIER, Frank, RATSCH, Boris A, ENNS, Andreas, LOO, Alice, LIQING CHEN, LENZ, Peter, WATERS, Nigel J, SCHULER, Walter, DÖRKEN, Bernd

“…The activated B-cell-like (ABC) subtype of diffuse large B-cell lymphoma (DLBCL) correlates with poor prognosis. The ABC subtype of DLBCL is associated with…”
Get full text

High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization by Naylor, Tara L, Greshock, Joel, Wang, Yan, Colligon, Theresa, Yu, Q C, Clemmer, Virginia, Zaks, Tal Z, Weber, Barbara L

“…Genomic aberrations in the form of subchromosomal DNA copy number changes are a hallmark of epithelial cancers, including breast cancer. The goal of the…”
Get full text

Characterization CSMD1 in a large set of primary lung, head and neck, breast and skin cancer tissues by Ma, Changqing, Quesnelle, Kelly M., Sparano, Anthony, Rao, Shilpa, Park, Min S., Cohen, Marc A., Wang, Yan, Samanta, Minu, Kumar, Madhu S., Aziz, M. Usman, Naylor, Tara L., Weber, Barbara, Fakharzadeh, Steven S., Weinstein, Gregory S., Vachani, Anil, D. Feldman, Michael, Brose, Marcia S.

“…The Cub and Sushi Multiple Domains-1 (CSMD1) is a tumor suppressor gene on 8p23.2, where allelic loss is both frequent and associated with poor prognosis in…”
Get full text

Estrogen Receptor Status Could Modulate the Genomic Pattern in Familial and Sporadic Breast Cancer by MELCHOR, Lorenzo, HONRADO, Emiliano, CIGUDOSA, Juan C, RAHMAN, Nazneen, NATHANSON, Katherine L, BENITEZ, Javier, JIA HUANG, ALVAREZ, Sara, NAYLOR, Tara L, GARCIA, Maria J, OSORIO, Ana, BLESA, David, STRATTON, Michael R, WEBER, Barbara L

“…Purpose: Familial breast cancer represents 5% to 10% of all breast tumors. Mutations in the two known major breast cancer susceptibility genes, BRCA1 and BRCA2…”
Get full text

Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization by JÖNSSON, Goran, NAYLOR, Tara L, STRATTON, Michael, RINGNER, Markus, BORG, Ake, WEBER, Barbara L, VALLON-CHRISTERSSON, Johan, STAAF, Johan, JIA HUANG, WARD, M. Renee, GRESHOCK, Joel D, LUTS, Lena, OLSSON, Hakan, RAHMAN, Nazneen

“…Mutations in BRCA1 and BRCA2 account for a significant proportion of hereditary breast cancers. Earlier studies have shown that inherited and sporadic tumors…”
Get full text

1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis by Greshock, Joel, Naylor, Tara L, Margolin, Adam, Diskin, Sharon, Cleaver, Stephen H, Futreal, P Andrew, deJong, Pieter J, Zhao, Shaying, Liebman, Michael, Weber, Barbara L

“…Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology…”
Get full text

CGHAnalyzer: a stand-alone software package for cancer genome analysis using array-based DNA copy number data by Margolin, Adam A., Greshock, Joel, Naylor, Tara L., Mosse, Yael, Maris, John M., Bignell, Graham, Saeed, Alexander I., Quackenbush, John, Weber, Barbara L.

“…This synopsis provides an overview of array-based comparative genomic hybridization data display, abstraction and analysis using CGHAnalyzer, a software suite,…”
Get full text

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response by Gao, Hui, Korn, Joshua M, Ferretti, Stéphane, Monahan, John E, Wang, Youzhen, Singh, Mallika, Zhang, Chao, Schnell, Christian, Yang, Guizhi, Zhang, Yun, Balbin, O Alejandro, Barbe, Stéphanie, Cai, Hongbo, Casey, Fergal, Chatterjee, Susmita, Chiang, Derek Y, Chuai, Shannon, Cogan, Shawn M, Collins, Scott D, Dammassa, Ernesta, Ebel, Nicolas, Embry, Millicent, Green, John, Kauffmann, Audrey, Kowal, Colleen, Leary, Rebecca J, Lehar, Joseph, Liang, Ying, Loo, Alice, Lorenzana, Edward, Robert McDonald, E, McLaughlin, Margaret E, Merkin, Jason, Meyer, Ronald, Naylor, Tara L, Patawaran, Montesa, Reddy, Anupama, Röelli, Claudia, Ruddy, David A, Salangsang, Fernando, Santacroce, Francesca, Singh, Angad P, Tang, Yan, Tinetto, Walter, Tobler, Sonja, Velazquez, Roberto, Venkatesan, Kavitha, Von Arx, Fabian, Wang, Hui Qin, Wang, Zongyao, Wiesmann, Marion, Wyss, Daniel, Xu, Fiona, Bitter, Hans, Atadja, Peter, Lees, Emma, Hofmann, Francesco, Li, En, Keen, Nicholas, Cozens, Robert, Jensen, Michael Rugaard, Pryer, Nancy K, Williams, Juliet A, Sellers, William R

“…The authors implement a collection of patient-derived xenograft tumors to test cancer drug responses. Profiling candidate therapeutics with limited cancer…”
Get full text

O25: Analysis of the genetic similarity of 10 cancer types using genome copy number data by Greshock, Joel, Mosse, Yael, Naylor, Tara L., Brose, Marsha, Huang, Jia, Fakharzadeh, Steve, Martin, Anne Marie, Athenasiadis, Galene, Ward, Renee, Medina, Angelica, Diskin, Sharon, Zaks, Tal Z., Brown, James, Maris, John M., Weber, Barbara L.

Get full text