Search Results - "NAYAL, Narendra"

An Improved Small-Molecule Inhibitor of FtsZ with Superior In Vitro Potency, Drug-Like Properties, and In Vivo Efficacy by STOKES, Neil R, BAKER, Nicola, MITCHELL, Jeffrey P, NAYAL, Narendra, YADAV, Anju, SRIVASTAVA, Anil, HAYDON, David J, BENNETT, James M, BERRY, Joanne, COLLINS, Ian, CZAPLEWSKI, Lloyd G, LOGAN, Alastair, MACDONALD, Rebecca, MACLEOD, Leanne, PEASLEY, Hilary

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Design, synthesis and structure-activity relationships of substituted oxazole-benzamide antibacterial inhibitors of FtsZ by Stokes, Neil R, Baker, Nicola, Bennett, James M, Chauhan, Pramod K, Collins, Ian, Davies, David T, Gavade, Maruti, Kumar, Dushyant, Lancett, Paul, Macdonald, Rebecca, Macleod, Leanne, Mahajan, Anu, Mitchell, Jeffrey P, Nayal, Narendra, Nayal, Yashodanand Nandan, Pitt, Gary R W, Singh, Mahipal, Yadav, Anju, Srivastava, Anil, Czaplewski, Lloyd G, Haydon, David J

“…The design, synthesis and structure-activity relationships of a series of oxazole-benzamide inhibitors of the essential bacterial cell division protein FtsZ…”
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Creating an Antibacterial with in Vivo Efficacy: Synthesis and Characterization of Potent Inhibitors of the Bacterial Cell Division Protein FtsZ with Improved Pharmaceutical Properties by Haydon, David J, Bennett, James M, Brown, David, Collins, Ian, Galbraith, Greta, Lancett, Paul, Macdonald, Rebecca, Stokes, Neil R, Chauhan, Pramod K, Sutariya, Jignesh K, Nayal, Narendra, Srivastava, Anil, Beanland, Joy, Hall, Robin, Henstock, Vincent, Noula, Caterina, Rockley, Chris, Czaplewski, Lloyd

“…3-Methoxybenzamide (1) is a weak inhibitor of the essential bacterial cell division protein FtsZ. Alkyl derivatives of 1 are potent antistaphylococcal…”
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Design, synthesis and structure-activity relationships of substituted oxazoleabenzamide antibacterial inhibitors of FtsZ by Stokes, Neil, Baker, Nicola, Bennett, James, Chauhan, Pramod, Collins, Ian, Davies, David, Gavade, Maruti, Kumar, Dushyant, Lancett, Paul, Macdonald, Rebecca, MacLeod, Leanne, Mahajan, Anu, Mitchell, Jeffrey, Nayal, Narendra, Nayal, Yashodanand, Pitt, Gary, Singh, Mahipal, Yadav, Anju, Srivastava, Anil, Czaplewski, Lloyd, Haydon, David

“…The design, synthesis and structure-activity relationships of a series of oxazoleabenzamide inhibitors of the essential bacterial cell division protein FtsZ…”
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