Search Results - "NAVARRO, H. A"

Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse by Raleigh, M D, Peterson, S J, Laudenbach, M, Baruffaldi, F, Carroll, F I, Comer, S D, Navarro, H A, Langston, T L, Runyon, S P, Winston, S, Pravetoni, M, Pentel, P R

“…Among vaccines aimed at treating substance use disorders, those targeting opioids present several unique medication development challenges. 1) Opioid overdose…”
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Patterns of significant seismic quiescence on the Mexican Pacific coast by Muñoz-Diosdado, A., Rudolf-Navarro, A.H., Angulo-Brown, F., Barrera-Ferrer, A.G.

“…•Actualization of the Schreider algorithm.•In the last decades main earthquakes on the Mexican Pacific coast were preceded by seismic quiescence.•A new color…”
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Some Common Features Between a Spring-Block Self-Organized Critical Model, Stick–Slip Experiments with Sandpapers and Actual Seismicity by Perez-Oregon, J., Muñoz-Diosdado, A., Rudolf-Navarro, A. H., Angulo-Brown, F.

“…In this article we stand out that actual seismicity, stick–slip experiments with sandpapers and a self-organized critical (SOC) model (Olami et al. Phys Rev…”
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Novel strategies for the discovery of plant-derived anticancer agents by Kinghorn, A. D., Farnsworth, Norman R., Soejarto, D. D., Cordell, G. A., Pezzuto, J. M., Udeani, G. O., Wani, M. C., Wall, M. E., Navarro, H. A., Kramer, R. A., Menendez, A. T., Fairchild, Craig R., Lane, K. E., Forenza, Salvatore, Vyas, D. M., Lam, K. S., Shu, Y.-Z.

“…Abstract…”
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Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2-exo-2-(2‘-Substituted 5‘-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Epibatidine Analogues by Carroll, F. Ivy, Liang, Feng, Navarro, Hernán A, Brieaddy, Lawrence E, Abraham, Philip, Damaj, M. I, Martin, Billy R

“…A convenient, high-yield synthesis of 7-tert-butoxycarbonyl-7-azabicyclo[2.2.1]hept-2-ene (5), which involved the addition of tributyltin hydride to…”
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On the possible correlation between the Gutenberg-Richter parameters of the frequency-magnitude relationship by Perez-Oregon, J., Muñoz-Diosdado, A., Rudolf-Navarro, A. H., Guzmán-Sáenz, A., Angulo-Brown, F.

“…The study of the Gutenberg-Richter (GR) parameters a and b has been very important to describe and characterize the seismicity over the different seismic…”
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Synthesis and Nicotinic Acetylcholine Receptor Binding Properties of exo-2-(2‘-Fluoro-5‘-pyridinyl)-7-azabicyclo- [2.2.1]heptane:  A New Positron Emission Tomography Ligand for Nicotinic Receptors by Liang, Feng, Navarro, Hernán A, Abraham, Philip, Kotian, Pravin, Ding, Yu-Shin, Fowler, Joanna, Volkow, Nora, Kuhar, Michael J, Carroll, F. Ivy

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Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. Evidence for cholinergic trophic influences in developing brain by Navarro, H A, Seidler, F J, Eylers, J P, Baker, F E, Dobbins, S S, Lappi, S E, Slotkin, T A

“…The development of cholinergic systems in brain regions was evaluated biochemically in developing control rats and rats whose mothers received nicotine via…”
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Macharistol, a New Cytotoxic Cinnamylphenol from the Stems of Machaerium aristulatum by SEO, Eun-Kyoung, KIM, Nam-Cheol, MI, Qiuwen, CHAI, Heebyung, WALL, Monroe E., WANI, Mansukh C., NAVARRO, Hernán A., BURGESS, Jason P., GRAHAM, James G., CABIESES, Fernando, TAN, Ghee T., FARNSWORTH, Norman R., PEZZUTO, John M., KINGHORN, A. Douglas

“…A new cinnamylphenol, macharistol (1), along with a known pterocarpan, (+)-medicarpin (2), were isolated as cytotoxic constituents from the stems of Machaerium…”
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Synthesis, Nicotinic Acetylcholine Receptor Binding, and Antinociceptive Properties of 2-exo-2-(2‘-Substituted-3‘-phenyl-5‘-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel Nicotinic Antagonist by Carroll, F. Ivy, Lee, Jeffrey R, Navarro, Hernán A, Brieaddy, Lawrence E, Abraham, Philip, Damaj, M. I, Martin, Billy R

“…A series of 2‘-substituted-3‘-phenyl epibatidine analogues were synthesized and evaluated for inhibition of binding at nicotine acetylcholine receptors and for…”
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In vitro and in vivo characterization of [125I]iodomethyllycaconitine in the rat by Navarro, H.A., Xu, H., Zhong, D., Abraham, P., Carroll, F.I.

“…The in vitro and in vivo binding characteristics of [125I]iodomethyllycaconitine ([125I]iodoMLA) were determined in the rat. [125I]iodoMLA binding to rat…”
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Prenatal exposure to nicotine via maternal infusions: effects on development of catecholamine systems by Navarro, H A, Seidler, F J, Whitmore, W L, Slotkin, T A

“…The effects of a continuous 16-day gestational exposure to nicotine on development of central and peripheral catecholaminergic pathways were examined in the…”
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Prenatal exposure to nicotine impairs nervous system development at a dose which does not affect viability or growth by Navarro, H A, Seidler, F J, Schwartz, R D, Baker, F E, Dobbins, S S, Slotkin, T A

“…Prenatal exposure to high doses of nicotine (greater than 6 mg/kg/day) via maternal infusions has been shown to impair nervous system development and to…”
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Gestational nicotine exposure alone or in combination with ethanol down-modulates offspring immune function by Basta, P.V, Basham, K.B, Ross, W.P, Brust, M.E, Navarro, H.A

“…Prenatal nicotine exposure has been shown to disrupt the development of a number of peripheral organs. In the current study, we examined the effects of…”
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Phosphatidic acid phosphatase in neonatal rat lung: effects of prenatal dexamethasone or terbutaline treatment on basal activity and on responsiveness to beta adrenergic stimulation by Kudlacz, E M, Navarro, H A, Slotkin, T A

“…Phosphatidic acid phosphatase (PAPase) is a key enzyme in the synthesis of lung surfactant. This study compares the effects of prenatal exposure (gestational…”
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Fetal nicotine exposure produces postnatal up-regulation of adenylate cyclase activity in peripheral tissues by Slotkin, T A, Navarro, H A, McCook, E C, Seidler, F J

“…Gestational exposure to nicotine has been shown to affect development of noradrenergic activity in both the central and peripheral nervous systems. In the…”
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Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect? by Navarro, H.A, Basta, P.V, Seidler, F.J, Slotkin, T.A

“…Neural input plays a key role in the establishment of immune function, and environmental agents or drugs that interfere with the development of the nervous…”
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Prenatal exposure to propranolol via continuous maternal infusion: effects on physiological and biochemical processes mediated by beta adrenergic receptors in fetal and neonatal rat lung by Kudlacz, E M, Navarro, H A, Eylers, J P, Slotkin, T A

“…During lung development, beta adrenergic receptors undergo transient coupling to enzymes and physiological processes which govern respiratory function and…”
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Amplitude–frequency relationship obtained using Hamiltonian approach for oscillators with sum of non-integer order nonlinearities by Navarro, H.A., Cveticanin, L.

“…In this paper the Hamiltonian approximate analytical approach is extended for solving vibrations of conservative oscillators with the sum of integer and/or…”
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Prenatal nicotine exposure impairs beta-adrenergic function: persistent chronotropic subsensitivity despite recovery from deficits in receptor binding by Navarro, H A, Mills, E, Seidler, F J, Baker, F E, Lappi, S E, Tayyeb, M I, Spencer, J R, Slotkin, T A

“…Gestational exposure to nicotine has been shown to interfere with biochemical markers of development of central and peripheral noradrenergic activity. The…”
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