Search Results - "NAURECKAS, Edward T"

Associations between fungal and bacterial microbiota of airways and asthma endotypes by Sharma, Anukriti, Laxman, Bharathi, Naureckas, Edward T., Hogarth, D. Kyle, Sperling, Anne I., Solway, Julian, Ober, Carole, Gilbert, Jack A., White, Steven R.

“…The relationship between asthma, atopy, and underlying type 2 (T2) airway inflammation is complex. Although the bacterial airway microbiota is known to differ…”
Get full text

Corticosteroid therapy and airflow obstruction influence the bronchial microbiome, which is distinct from that of bronchoalveolar lavage in asthmatic airways by Denner, Darcy R., PhD, Sangwan, Naseer, PhD, Becker, Julia B., MD, Hogarth, D. Kyle, MD, Oldham, Justin, MD, Castillo, Jamee, MD, Sperling, Anne I., PhD, Solway, Julian, MD, Naureckas, Edward T., MD, Gilbert, Jack A., PhD, White, Steven R., MD

“…Background The lung has a diverse microbiome that is modest in biomass. This microbiome differs in asthmatic patients compared with control subjects, but the…”
Get full text

Airway Inflammation after Bronchial Thermoplasty for Severe Asthma by Denner, Darcy R, Doeing, Diana C, Hogarth, D Kyle, Dugan, Karen, Naureckas, Edward T, White, Steven R

“…Bronchial thermoplasty is an alternative treatment for patients with severe, uncontrolled asthma in which the airway smooth muscle is eliminated using…”
Get full text

Discerning asthma endotypes through comorbidity mapping by Jia, Gengjie, Zhong, Xue, Im, Hae Kyung, Schoettler, Nathan, Pividori, Milton, Hogarth, D. Kyle, Sperling, Anne I., White, Steven R., Naureckas, Edward T., Lyttle, Christopher S., Terao, Chikashi, Kamatani, Yoichiro, Akiyama, Masato, Matsuda, Koichi, Kubo, Michiaki, Cox, Nancy J., Ober, Carole, Rzhetsky, Andrey, Solway, Julian

“…Asthma is a heterogeneous, complex syndrome, and identifying asthma endotypes has been challenging. We hypothesize that distinct endotypes of asthma arise in…”
Get full text

Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region by Aneas, Ivy, Decker, Donna C., Howard, Chanie L., Sobreira, Débora R., Sakabe, Noboru J., Blaine, Kelly M., Stein, Michelle M., Hrusch, Cara L., Montefiori, Lindsey E., Tena, Juan, Magnaye, Kevin M., Clay, Selene M., Gern, James E., Jackson, Daniel J., Altman, Matthew C., Naureckas, Edward T., Hogarth, Douglas K., White, Steven R., Gomez-Skarmeta, Jose Luis, Schoetler, Nathan, Ober, Carole, Sperling, Anne I., Nóbrega, Marcelo A.

“…Genome-wide association studies (GWAS) have implicated the IL33 locus in asthma, but the underlying mechanisms remain unclear. Here, we identify a 5 kb region…”
Get full text

Evidence for an IL-6–high asthma phenotype in asthmatic patients of African ancestry by White, Steven R., Laxman, Bharathi, Naureckas, Edward T., Hogarth, D. Kyle, Solway, Julian, Sperling, Anne I., Ober, Carole

“…Importantly, the cohorts had a racial balance that was majority white (62% and 66%), with relatively few African Americans (11% and 23%). Because African…”
Get full text

The Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Diagnosis Codes for Identifying Patients Hospitalized for COPD Exacerbations by Stein, Brian D., MD, Bautista, Adriana, MD, Schumock, Glen T., PharmD, Lee, Todd A., PharmD, PhD, Charbeneau, Jeffery T., MS, Lauderdale, Diane S., PhD, Naureckas, Edward T., MD, FCCP, Meltzer, David O., MD, PhD, Krishnan, Jerry A., MD, PhD, FCCP

“…Background Acute exacerbations of COPD (AE-COPD) are a leading cause of hospitalizations in the United States. To estimate the burden of disease (eg,…”
Get full text

Elevated levels of soluble humanleukocyte antigen-G in the airways are a marker for a low-inflammatory endotype of asthma by White, Steven R., MD, Nicodemus-Johnson, Jessie, PhD, Laxman, Bharathi, PhD, Denner, Darcy R., PhD, Naureckas, Edward T., MD, Hogarth, D. Kyle, MD, Stern, Randi, MS, Minc, Alexa, BA, Solway, Julian, MD, Sperling, Anne, PhD, Ober, Carole, PhD

“…Previous studies have suggested that markers of TH2-associated inflammation in asthma predict clinical responsiveness or resistance to corticosteroid…”
Get full text

Maternal asthma and microRNA regulation of soluble HLA-G in the airway by Nicodemus-Johnson, Jessie, PhD, Laxman, Bharathi, PhD, Stern, Randi K., BS, Sudi, Jyotsna, MS, Tierney, Courtney N., MPH, Norwick, Lourdes, RN, Hogarth, Douglas K., MD, McConville, John F., MD, Naureckas, Edward T., MD, Sperling, Anne I., PhD, Solway, Julian, MD, Krishnan, Jerry A., MD, PhD, Nicolae, Dan L., PhD, White, Steven R., MD, Ober, Carole, PhD

“…Background We previously reported an interaction between maternal asthma and the child's HLA-G genotype on the child's subsequent risk for asthma. The…”
Get full text

Genetic-Epigenetic Interactions in Asthma Revealed by a Genome-Wide Gene-Centric Search by Kogan, Vladimir, Millstein, Joshua, London, Stephanie J, Ober, Carole, White, Steven R, Naureckas, Edward T, Gauderman, W James, Jackson, Daniel J, Barraza-Villarreal, Albino, Romieu, Isabelle, Raby, Benjamin A, Breton, Carrie V

“…There is evidence to suggest that asthma pathogenesis is affected by both genetic and epigenetic variation independently, and there is some evidence to suggest…”
Get more information

An Umbrella Review: Corticosteroid Therapy for Adults with Acute Asthma by Krishnan, Jerry A., MD, PhD, Davis, Steven Q., MD, MS, Naureckas, Edward T., MD, Gibson, Peter, MBBS, Rowe, Brian H., MD, MSc

“…Abstract The objective of this “umbrella” review is to synthesize the evidence and provide clinicians a single report that summarizes the state of knowledge…”
Get full text

Non―Cystic Fibrosis Bronchiectasis by MCSHANE, Pamela J, NAURECKAS, Edward T, TINO, Gregory, STREK, Mary E

“…There is renewed interest in non-cystic fibrosis bronchiectasis, which is a cause of significant morbidity in adults and can be diagnosed by high-resolution…”
Get full text

The metabolic footprint of the airway bacterial community in cystic fibrosis by Narayanamurthy, Vaishnavi, Sweetnam, John M, Denner, Darcy R, Chen, Lena W, Naureckas, Edward T, Laxman, Bharathi, White, Steven R

“…Progressive, chronic bacterial infection of the airways is a leading cause of death in cystic fibrosis (CF). Culture-independent methods based on sequencing of…”
Get full text

High frequency chest wall oscillation for asthma and chronic obstructive pulmonary disease exacerbations: a randomized sham-controlled clinical trial by Mahajan, Amit K, Diette, Gregory B, Hatipoğlu, Umur, Bilderback, Andrew, Ridge, Alana, Harris, Vanessa Walker, Dalapathi, Vijay, Badlani, Sameer, Lewis, Stephanie, Charbeneau, Jeff T, Naureckas, Edward T, Krishnan, Jerry A

“…High frequency chest wall oscillation (HFCWO) is used for airway mucus clearance. The objective of this study was to evaluate the use of HFCWO early in the…”
Get full text

Confirmatory spirometry for adults hospitalized with a diagnosis of asthma or chronic obstructive pulmonary disease exacerbation by Prieto Centurion, Valentin, Huang, Frank, Naureckas, Edward T, Camargo, Jr, Carlos A, Charbeneau, Jeffrey, Joo, Min J, Press, Valerie G, Krishnan, Jerry A

“…Objective measurement of airflow obstruction by spirometry is an essential part of the diagnosis of asthma or COPD. During exacerbations, the feasibility and…”
Get full text

Cystic Fibrosis Pulmonary Guidelines: Chronic Medications for Maintenance of Lung Health by MOGAYZEL, Peter J, NAURECKAS, Edward T, ROBINSON, Karen A, MUELLER, Gary, HADJILIADIS, Denis, HOAG, Jeffrey B, LUBSCH, Lisa, HAZLE, Leslie, SABADOSA, Kathy, MARSHALL, Bruce

“…Cystic fibrosis (CF) is an autosomal recessive disease characterized by abnormal airways secretions, chronic endobronchial infection, and progressive airway…”
Get full text

Embedding research recruitment in a community resource e-prescribing system: lessons from an implementation study on Chicago's South Side by Feldmeth, Gillian, Naureckas, Edward T, Solway, Julian, Lindau, Stacy Tessler

“…The study sought to implement and assess the CommunityRx e-prescribing system to recruit research participants from a predominantly non-Hispanic Black…”
Get full text

Bronchiectasis in a Diverse US Population: Effects of Ethnicity on Etiology and Sputum Culture by MCSHANE, Pamela J, NAURECKAS, Edward T, STREK, Mary E

“…Previous studies of patients with bronchiectasis have found that the cause is idiopathic in the majority of cases, but these studies were done in homogeneous…”
Get full text

A-to-I editing of miR-200b-3p in airway cells is associated with moderate-to-severe asthma by Magnaye, Kevin M, Naughton, Katherine A, Huffman, Janel, Hogarth, D Kyle, Naureckas, Edward T, White, Steven R, Ober, Carole

“…Asthma is a chronic lung disease characterised by persistent airway inflammation. Altered microRNA (miRNA)-mediated gene silencing in bronchial epithelial…”
Get full text

Teaching the Use of Respiratory Inhalers to Hospitalized Patients with Asthma or COPD: a Randomized Trial by Press, Valerie G., Arora, Vineet M., Shah, Lisa M., Lewis, Stephanie L., Charbeneau, Jeffery, Naureckas, Edward T., Krishnan, Jerry A.

“…ABSTRACT BACKGROUND Hospitalized patients frequently misuse their respiratory inhalers, yet it is unclear what the most effective hospital-based educational…”
Get full text