Search Results - "NAUME, Bjørn"

Circulating Tumor Cells in Breast Cancer Patients Treated by Neoadjuvant Chemotherapy: A Meta-analysis by Bidard, François-Clément, Michiels, Stefan, Riethdorf, Sabine, Mueller, Volkmar, Esserman, Laura J, Lucci, Anthony, Naume, Bjørn, Horiguchi, Jun, Gisbert-Criado, Rafael, Sleijfer, Stefan, Toi, Masakazu, Garcia-Saenz, Jose A, Hartkopf, Andreas, Generali, Daniele, Rothé, Françoise, Smerage, Jeffrey, Muinelo-Romay, Laura, Stebbing, Justin, Viens, Patrice, Magbanua, Mark Jesus M, Hall, Carolyn S, Engebraaten, Olav, Takata, Daisuke, Vidal-Martínez, José, Onstenk, Wendy, Fujisawa, Noriyoshi, Diaz-Rubio, Eduardo, Taran, Florin-Andrei, Cappelletti, Maria Rosa, Ignatiadis, Michail, Proudhon, Charlotte, Wolf, Denise M, Bauldry, Jessica B, Borgen, Elin, Nagaoka, Rin, Carañana, Vicente, Kraan, Jaco, Maestro, Marisa, Brucker, Sara Yvonne, Weber, Karsten, Reyal, Fabien, Amara, Dominic, Karhade, Mandar G, Mathiesen, Randi R, Tokiniwa, Hideaki, Llombart-Cussac, Antonio, Meddis, Alessandra, Blanche, Paul, d'Hollander, Koenraad, Cottu, Paul, Park, John W, Loibl, Sibylle, Latouche, Aurélien, Pierga, Jean-Yves, Pantel, Klaus

“…Abstract Background We conducted a meta-analysis in nonmetastatic breast cancer patients treated by neoadjuvant chemotherapy (NCT) to assess the clinical…”
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Allele-specific copy number analysis of tumors by Van Loo, Peter, Nordgard, Silje H., Lingjærde, Ole Christian, Russnes, Hege G., Rye, Inga H., Sun, Wei, Weigman, Victor J., Marynen, Peter, Zetterberg, Anders, Naume, Bjørn, Perou, Charles M., Børresen-Dale, Anne-Lise, Kristensen, Vessela N.

“…We present an allele-specific copy number analysis of the in vivo breast cancer genome. We describe a unique bioinformatics approach, ASCAT (allele-specific…”
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An independent poor-prognosis subtype of breast cancer defined by a distinct tumor immune microenvironment by Tekpli, Xavier, Lien, Tonje, Røssevold, Andreas Hagen, Nebdal, Daniel, Borgen, Elin, Ohnstad, Hege Oma, Kyte, Jon Amund, Vallon-Christersson, Johan, Fongaard, Marie, Due, Eldri Undlien, Svartdal, Lisa Gregusson, Sveli, My Anh Tu, Garred, Øystein, Frigessi, Arnoldo, Sahlberg, Kristine Kleivi, Sørlie, Therese, Russnes, Hege G., Naume, Bjørn, Kristensen, Vessela N.

“…How mixtures of immune cells associate with cancer cell phenotype and affect pathogenesis is still unclear. In 15 breast cancer gene expression datasets, we…”
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Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome by Aure, Miriam Ragle, Vitelli, Valeria, Jernström, Sandra, Kumar, Surendra, Krohn, Marit, Due, Eldri U, Haukaas, Tonje Husby, Leivonen, Suvi-Katri, Vollan, Hans Kristian Moen, Lüders, Torben, Rødland, Einar, Vaske, Charles J, Zhao, Wei, Møller, Elen K, Nord, Silje, Giskeødegård, Guro F, Bathen, Tone Frost, Caldas, Carlos, Tramm, Trine, Alsner, Jan, Overgaard, Jens, Geisler, Jürgen, Bukholm, Ida R K, Naume, Bjørn, Schlichting, Ellen, Sauer, Torill, Mills, Gordon B, Kåresen, Rolf, Mælandsmo, Gunhild M, Lingjærde, Ole Christian, Frigessi, Arnoldo, Kristensen, Vessela N, Børresen-Dale, Anne-Lise, Sahlberg, Kristine K

“…Breast cancer is a heterogeneous disease at the clinical and molecular level. In this study we integrate classifications extracted from five different…”
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miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors by Enerly, Espen, Steinfeld, Israel, Kleivi, Kristine, Leivonen, Suvi-Katri, Aure, Miriam R, Russnes, Hege G, Rønneberg, Jo Anders, Johnsen, Hilde, Navon, Roy, Rødland, Einar, Mäkelä, Rami, Naume, Bjørn, Perälä, Merja, Kallioniemi, Olli, Kristensen, Vessela N, Yakhini, Zohar, Børresen-Dale, Anne-Lise

“…Few studies have performed expression profiling of both miRNA and mRNA from the same primary breast carcinomas. In this study we present and analyze data…”
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Breast cancer quantitative proteome and proteogenomic landscape by Johansson, Henrik J., Socciarelli, Fabio, Vacanti, Nathaniel M., Haugen, Mads H., Zhu, Yafeng, Siavelis, Ioannis, Fernandez-Woodbridge, Alejandro, Aure, Miriam R., Sennblad, Bengt, Vesterlund, Mattias, Branca, Rui M., Orre, Lukas M., Huss, Mikael, Fredlund, Erik, Beraki, Elsa, Garred, Øystein, Boekel, Jorrit, Sauer, Torill, Zhao, Wei, Nord, Silje, Höglander, Elen K., Jans, Daniel C., Brismar, Hjalmar, Haukaas, Tonje H., Bathen, Tone F., Schlichting, Ellen, Naume, Bjørn, Luders, Torben, Borgen, Elin, Kristensen, Vessela N., Russnes, Hege G., Lingjærde, Ole Christian, Mills, Gordon B., Sahlberg, Kristine K., Børresen-Dale, Anne-Lise, Lehtiö, Janne

“…In the preceding decades, molecular characterization has revolutionized breast cancer (BC) research and therapeutic approaches. Presented herein, an unbiased…”
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Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing by Demeulemeester, Jonas, Kumar, Parveen, Møller, Elen K, Nord, Silje, Wedge, David C, Peterson, April, Mathiesen, Randi R, Fjelldal, Renathe, Zamani Esteki, Masoud, Theunis, Koen, Fernandez Gallardo, Elia, Grundstad, A Jason, Borgen, Elin, Baumbusch, Lars O, Børresen-Dale, Anne-Lise, White, Kevin P, Kristensen, Vessela N, Van Loo, Peter, Voet, Thierry, Naume, Bjørn

“…Single-cell micro-metastases of solid tumors often occur in the bone marrow. These disseminated tumor cells (DTCs) may resist therapy and lay dormant or…”
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A Pooled Analysis of Bone Marrow Micrometastasis in Breast Cancer by Braun, Stephan, Vogl, Florian D, Naume, Bjørn, Janni, Wolfgang, Osborne, Michael P, Coombes, R. Charles, Schlimok, Günter, Diel, Ingo J, Gerber, Bernd, Gebauer, Gerhard, Pierga, Jean-Yves, Marth, Christian, Oruzio, Daniel, Wiedswang, Gro, Solomayer, Erich-Franz, Kundt, Günther, Strobl, Barbara, Fehm, Tanja, Wong, George Y.C, Bliss, Judith, Vincent-Salomon, Anne, Pantel, Klaus

“…In a pooled analysis of nine clinical trials involving almost 5000 women with breast cancer who underwent examination of the bone marrow for metastatic cancer…”
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DNA methylation at enhancers identifies distinct breast cancer lineages by Fleischer, Thomas, Tekpli, Xavier, Mathelier, Anthony, Wang, Shixiong, Nebdal, Daniel, Dhakal, Hari P., Sahlberg, Kristine Kleivi, Schlichting, Ellen, Børresen-Dale, Anne-Lise, Borgen, Elin, Naume, Bjørn, Eskeland, Ragnhild, Frigessi, Arnoldo, Tost, Jörg, Hurtado, Antoni, Kristensen, Vessela N.

“…Breast cancers exhibit genome-wide aberrant DNA methylation patterns. To investigate how these affect the transcriptome and which changes are linked to…”
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The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer by Silwal-Pandit, Laxmi, Nord, Silje, von der Lippe Gythfeldt, Hedda, Møller, Elen K, Fleischer, Thomas, Rødland, Einar, Krohn, Marit, Borgen, Elin, Garred, Øystein, Olsen, Tone, Vu, Phuong, Skjerven, Helle, Fangberget, Anne, Holmen, Marit M, Schlitchting, Ellen, Wille, Elisabeth, Nordberg Stokke, Mette, Moen Vollan, Hans Kristian, Kristensen, Vessela, Langerød, Anita, Lundgren, Steinar, Wist, Erik, Naume, Bjørn, Lingjærde, Ole Christian, Børresen-Dale, Anne-Lise, Engebraaten, Olav

“…Chemotherapy-induced alterations to gene expression are due to transcriptional reprogramming of tumor cells or subclonal adaptations to treatment. The effect…”
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Disseminated tumour cells from the bone marrow of early breast cancer patients: Results from an international pooled analysis by Hartkopf, Andreas D., Brucker, Sara Y., Taran, Florin-Andrei, Harbeck, Nadia, von Au, Alexandra, Naume, Bjørn, Pierga, Jean-Yves, Hoffmann, Oliver, Beckmann, Matthias W., Rydén, Lisa, Fehm, Tanja, Aft, Rebecca, Solà, Montserrat, Walter, Vincent, Rack, Brigitte, Schuetz, Florian, Borgen, Elin, Ta, Minh-Hanh, Bittner, Ann-Kathrin, Fasching, Peter A., Fernö, Mårten, Krawczyk, Natalia, Weilbaecher, Katherine, Margelí, Mireia, Hahn, Markus, Jueckstock, Julia, Domschke, Christoph, Bidard, Francois-Clement, Kasimir-Bauer, Sabine, Schoenfisch, Birgitt, Kurt, Ayse G., Wallwiener, Markus, Gebauer, Gerhard, Klein, Christoph A., Wallwiener, Diethelm, Janni, Wolfgang, Pantel, Klaus

“…Presence of disseminated tumour cells (DTCs) in the bone marrow (BM) has been described as a surrogate of residual disease in patients with early breast cancer…”
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Noninvasive profiling of serum cytokines in breast cancer patients and clinicopathological characteristics by Jabeen, Shakila, Espinoza, Jaime A., Torland, Lilly Anne, Zucknick, Manuela, Kumar, Surendra, Haakensen, Vilde D., Lüders, Torben, Engebraaten, Olav, Børresen-Dale, Anne-Lise, Kyte, Jon Amund, Gromov, Pavel, Naume, Bjørn, Kristensen, Vessela, Gromova, Irina, Tekpli, Xavier

“…Cancers elicit an immune response by modifying the microenvironment. The immune system plays a pivotal role in cancer recognition and eradication. While the…”
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RNA sequencing-based single sample predictors of molecular subtype and risk of recurrence for clinical assessment of early-stage breast cancer by Staaf, Johan, Häkkinen, Jari, Hegardt, Cecilia, Saal, Lao H., Kimbung, Siker, Hedenfalk, Ingrid, Lien, Tonje, Sørlie, Therese, Naume, Bjørn, Russnes, Hege, Marcone, Rachel, Ayyanan, Ayyakkannu, Brisken, Cathrin, Malterling, Rebecka R., Asking, Bengt, Olofsson, Helena, Lindman, Henrik, Bendahl, Pär-Ola, Ehinger, Anna, Larsson, Christer, Loman, Niklas, Rydén, Lisa, Malmberg, Martin, Borg, Åke, Vallon-Christersson, Johan

“…Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop…”
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Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer by Lesurf, Robert, Aure, Miriam Ragle, Mørk, Hanne Håberg, Vitelli, Valeria, Sauer, Torill, Geisler, Jürgen, Hofvind, Solveig, Borgen, Elin, Børresen-Dale, Anne-Lise, Engebråten, Olav, Fodstad, Øystein, Garred, Øystein, Geitvik, Gry Aarum, Kåresen, Rolf, Naume, Bjørn, Mælandsmo, Gunhild Mari, Russnes, Hege G., Schlichting, Ellen, Sørlie, Therese, Lingjærde, Ole Christian, Kristensen, Vessela, Sahlberg, Kristine Kleivi, Skjerven, Helle Kristine, Fritzman, Britt, Lundgren, Steinar, Børresen-Dale, Anne-Lise, Kristensen, Vessela, Wärnberg, Fredrik, Hallett, Michael, Sørlie, Therese

“…Breast cancer consists of at least five main molecular “intrinsic” subtypes that are reflected in both pre-invasive and invasive disease. Although previous…”
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LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer by Sas‐Chen, Aldema, Aure, Miriam R, Leibovich, Limor, Carvalho, Silvia, Enuka, Yehoshua, Körner, Cindy, Polycarpou‐Schwarz, Maria, Lavi, Sara, Nevo, Nava, Kuznetsov, Yuri, Yuan, Justin, Azuaje, Francisco, Ulitsky, Igor, Diederichs, Sven, Wiemann, Stefan, Yakhini, Zohar, Kristensen, Vessela N, Børresen‐Dale, Anne‐Lise, Yarden, Yosef, Sauer, Torill, Geisler, Jürgen, Hofvind, Solveig, Bathen, Tone F, Borgen, Elin, Engebråten, Olav, Fodstad, Øystein, Garred, Øystein, Geitvik, Gry Aarum, Kåresen, Rolf, Naume, Bjørn, Mælandsmo, Gunhild Mari, Russnes, Hege G, Schlichting, Ellen, Sørlie, Therese, Lingjærde, Ole Christian, Sahlberg, Kristine Kleivi, Skjerven, Helle Kristine, Fritzman, Britt

“…Long noncoding RNAs (lncRNAs) are emerging as regulators of gene expression in pathogenesis, including cancer. Recently, lncRNAs have been implicated in…”
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The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers by Knutsen, Erik, Lellahi, Seyed Mohammad, Aure, Miriam Ragle, Nord, Silje, Fismen, Silje, Larsen, Kenneth Bowitz, Gabriel, Marta Tellez, Hedberg, Annica, Bjørklund, Sunniva Stordal, Bofin, Anna Mary, Mælandsmo, Gunhild Mari, Sørlie, Therese, Mortensen, Elin Synnøve, Perander, Maria

“…The long non-coding RNA NEAT1 locus is transcribed into two overlapping isoforms, NEAT1_1 and NEAT1_2 , of which the latter is essential for the assembly of…”
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Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations by Höglander, Elen Kristine, Nord, Silje, Wedge, David C, Lingjærde, Ole Christian, Silwal-Pandit, Laxmi, Gythfeldt, Hedda vdL, Vollan, Hans Kristian Moen, Fleischer, Thomas, Krohn, Marit, Schlitchting, Ellen, Borgen, Elin, Garred, Øystein, Holmen, Marit M, Wist, Erik, Naume, Bjørn, Van Loo, Peter, Børresen-Dale, Anne-Lise, Engebraaten, Olav, Kristensen, Vessela

“…Chemotherapeutic agents such as anthracyclines and taxanes are commonly used in the neoadjuvant setting. Bevacizumab is an antibody which binds to vascular…”
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Novel patterns of genome rearrangement and their association with survival in breast cancer by Hicks, James, Krasnitz, Alexander, Lakshmi, B, Navin, Nicholas E, Riggs, Michael, Leibu, Evan, Esposito, Diane, Alexander, Joan, Troge, Jen, Grubor, Vladimir, Yoon, Seungtai, Wigler, Michael, Ye, Kenny, Børresen-Dale, Anne-Lise, Naume, Bjørn, Schlicting, Ellen, Norton, Larry, Hägerström, Torsten, Skoog, Lambert, Auer, Gert, Månér, Susanne, Lundin, Pär, Zetterberg, Anders

“…Representational Oligonucleotide Microarray Analysis (ROMA) detects genomic amplifications and deletions with boundaries defined at a resolution of…”
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Genomic architecture characterizes tumor progression paths and fate in breast cancer patients by Russnes, Hege G, Vollan, Hans Kristian Moen, Lingjærde, Ole Christian, Krasnitz, Alexander, Lundin, Pär, Naume, Bjørn, Sørlie, Therese, Borgen, Elin, Rye, Inga H, Langerød, Anita, Chin, Suet-Feung, Teschendorff, Andrew E, Stephens, Philip J, Månér, Susanne, Schlichting, Ellen, Baumbusch, Lars O, Kåresen, Rolf, Stratton, Michael P, Wigler, Michael, Caldas, Carlos, Zetterberg, Anders, Hicks, James, Børresen-Dale, Anne-Lise

“…Distinct molecular subtypes of breast carcinomas have been identified, but translation into clinical use has been limited. We have developed two…”
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Deep learning for automated scoring of immunohistochemically stained tumour tissue sections – Validation across tumour types based on patient outcomes by Kildal, Wanja, Cyll, Karolina, Kalsnes, Joakim, Islam, Rakibul, Julbø, Frida M., Pradhan, Manohar, Ersvær, Elin, Shepherd, Neil, Vlatkovic, Ljiljana, Tekpli, Xavier, Garred, Øystein, Kristensen, Gunnar B., Askautrud, Hanne A., Hveem, Tarjei S., Danielsen, Håvard E., Bathen, Tone F., Borgen, Elin, Børresen-Dale, Anne-Lise, Engebråten, Olav, Fritzman, Britt, Hartman-Johnsen, Olaf Johan, Garred, Øystein, Geisler, Jürgen, Geitvik, Gry Aarum, Hofvind, Solveig, Kåresen, Rolf, Langerød, Anita, Lingjærde, Ole Christian, Mælandsmo, Gunhild M., Naume, Bjørn, Russnes, Hege G., Sahlberg, Kristine Kleivi, Sauer, Torill, Skjerven, Helle Kristine, Schlichting, Ellen, Sørlie, Therese

“…We aimed to develop deep learning (DL) models to detect protein expression in immunohistochemically (IHC) stained tissue-sections, and to compare their…”
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