Search Results - "NATTEL, STANLEY"
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Molecular and Cellular Mechanisms of Atrial Fibrosis in Atrial Fibrillation
Published in JACC. Clinical electrophysiology (01-05-2017)“…Abstract Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Atrial fibrosis has emerged as an important pathophysiological…”
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Electrical coupling between cardiomyocytes and fibroblasts: experimental testing of a challenging and important concept
Published in Cardiovascular research (01-03-2018)Get full text
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The role of cellular senescence in cardiac disease: basic biology and clinical relevance
Published in Nature reviews cardiology (01-04-2022)“…Cellular senescence, classically defined as stable cell cycle arrest, is implicated in biological processes such as embryogenesis, wound healing and ageing…”
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Role of Inflammation in Atrial Fibrillation Pathophysiology and Management
Published in Circulation Journal (2015)“…Atrial fibrillation (AF) is the most common clinically relevant arrhythmia, but the methods available for treating AF and its complications (of which the most…”
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Atrial Fibrosis: Mechanisms and Clinical Relevance in Atrial Fibrillation
Published in Journal of the American College of Cardiology (26-02-2008)“…Atrial Fibrosis Mechanisms and Clinical Relevance in Atrial Fibrillation Brett Burstein, Stanley Nattel Atrial fibrillation (AF) is the most common arrhythmia…”
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Postoperative atrial fibrillation: mechanisms, manifestations and management
Published in Nature reviews cardiology (01-07-2019)“…Postoperative atrial fibrillation (POAF) complicates 20–40% of cardiac surgical procedures and 10–20% of non-cardiac thoracic operations. Typical features…”
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7
Atrial Remodeling and Atrial Fibrillation
Published in Journal of the American College of Cardiology (10-06-2014)“…Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. AF and its complications are responsible for important population…”
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Cellular and Molecular Electrophysiology of Atrial Fibrillation Initiation, Maintenance, and Progression
Published in Circulation research (25-04-2014)“…Atrial fibrillation (AF) is the most common clinically relevant arrhythmia and is associated with increased morbidity and mortality. The incidence of AF is…”
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Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
Published in Nature reviews cardiology (01-10-2016)“…Key Points Paroxysmal atrial fibrillation (pAF) has discrete clinical features from persistent forms, including greater relative pathophysiological importance…”
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New antiarrhythmic drugs for treatment of atrial fibrillation
Published in The Lancet (British edition) (03-04-2010)“…Summary Inadequacies in current therapies for atrial fibrillation have made new drug development crucial. Conventional antiarrhythmic drugs increase the risk…”
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Modifiable Risk Factors and Atrial Fibrillation
Published in Circulation (New York, N.Y.) (08-08-2017)“…There has been increasing focus on the rising burden of atrial fibrillation (AF) since the turn of the millennium. The AF epidemic is projected not only to…”
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Translational Challenges in Atrial Fibrillation
Published in Circulation research (02-03-2018)“…Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated with substantial morbidity and mortality. Current treatment…”
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13
Finding a new job: glutamate signaling acts in atrial cardiomyocytes
Published in Cell research (01-09-2021)Get full text
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14
New ideas about atrial fibrillation 50 years on
Published in Nature (London) (10-01-2002)“…Atrial fibrillation is a condition in which control of heart rhythm is taken away from the normal sinus node pacemaker by rapid activity in different areas…”
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15
Dronedarone in Atrial Fibrillation — Jekyll and Hyde?
Published in The New England journal of medicine (15-12-2011)“…Atrial fibrillation, the most common type of sustained cardiac arrhythmia, is associated with increased morbidity and mortality and is often therapeutically…”
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Recent advances in the molecular pathophysiology of atrial fibrillation
Published in The Journal of clinical investigation (01-08-2011)“…Atrial fibrillation (AF) is an extremely common cardiac rhythm disorder that causes substantial morbidity and contributes to mortality. The mechanisms…”
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Metabolic Considerations in Atrial Fibrillation ― Mechanistic Insights and Therapeutic Opportunities
Published in Circulation Journal (2017)“…Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice and is associated with morbidity and mortality. Over the past 2 decades,…”
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MicroRNAs and atrial fibrillation: mechanisms and translational potential
Published in Nature reviews cardiology (01-02-2015)“…Key Points MicroRNAs are gene regulators with important pathophysiological roles in various cardiac conditions, including in atrial fibrillation (AF) Patients…”
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Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation
Published in Circulation research (25-09-2020)“…Postoperative atrial fibrillation (POAF) is a common and troublesome complication of cardiac surgery. POAF is generally believed to occur when postoperative…”
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Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation
Published in Circulation (New York, N.Y.) (13-11-2018)“…BACKGROUND:Atrial fibrillation (AF) is frequently associated with enhanced inflammatory response. The NLRP3 (NACHT, LRR, and PYD domain containing protein 3)…”
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