Search Results - "NATHANSON, Jason L"

Differential L1 regulation in pluripotent stem cells of humans and apes by Marchetto, Maria C. N., Narvaiza, Iñigo, Denli, Ahmet M., Benner, Christopher, Lazzarini, Thomas A., Nathanson, Jason L., Paquola, Apuã C. M., Desai, Keval N., Herai, Roberto H., Weitzman, Matthew D., Yeo, Gene W., Muotri, Alysson R., Gage, Fred H.

“…Induced pluripotent stem-cell characterization reveals phenotypical differences between humans and non-human primates (NHPs): gene expression analysis shows…”
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High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells by D'Antonio, Matteo, Woodruff, Grace, Nathanson, Jason L., D'Antonio-Chronowska, Agnieszka, Arias, Angelo, Matsui, Hiroko, Williams, Roy, Herrera, Cheryl, Reyna, Sol M., Yeo, Gene W., Goldstein, Lawrence S.B., Panopoulos, Athanasia D., Frazer, Kelly A.

“…Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in…”
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Two-photon imaging of calcium in virally transfected striate cortical neurons of behaving monkey by Heider, Barbara, Nathanson, Jason L, Isacoff, Ehud Y, Callaway, Edward M, Siegel, Ralph M

“…Two-photon scanning microscopy has advanced our understanding of neural signaling in non-mammalian species and mammals. Various developments are needed to…”
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LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates Splicing Factor Abundance by Wilbert, Melissa L., Huelga, Stephanie C., Kapeli, Katannya, Stark, Thomas J., Liang, Tiffany Y., Chen, Stella X., Yan, Bernice Y., Nathanson, Jason L., Hutt, Kasey R., Lovci, Michael T., Kazan, Hilal, Vu, Anthony Q., Massirer, Katlin B., Morris, Quaid, Hoon, Shawn, Yeo, Gene W.

“…LIN28 is a conserved RNA-binding protein implicated in pluripotency, reprogramming, and oncogenesis. It was previously shown to act primarily by blocking let-7…”
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Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types by Nathanson, Jason L, Jappelli, Roberto, Scheeff, Eric D, Manning, Gerard, Obata, Kunihiko, Brenner, Sydney, Callaway, Edward M

“…Short cell-type specific promoter sequences are important for targeted gene therapy and studies of brain circuitry. We report on the ability of short promoter…”
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Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome by DE SOUSA ANDRADE, Luciana Nogueira, NATHANSON, Jason L, YEO, Gene W, MENCK, Carlos Frederico Martins, RENATO MUOTRI, Alysson

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Large-scale tethered function assays identify factors that regulate mRNA stability and translation by Luo, En-Ching, Nathanson, Jason L., Tan, Frederick E., Schwartz, Joshua L., Schmok, Jonathan C., Shankar, Archana, Markmiller, Sebastian, Yee, Brian A., Sathe, Shashank, Pratt, Gabriel A., Scaletta, Duy B., Ha, Yuanchi, Hill, David E., Aigner, Stefan, Yeo, Gene W.

“…The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting a major bottleneck to a full understanding of gene…”
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MicroRNA-101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks by Lippi, Giordano, Fernandes, Catarina C., Ewell, Laura A., John, Danielle, Romoli, Benedetto, Curia, Giulia, Taylor, Seth R., Frady, E. Paxon, Jensen, Anne B., Liu, Jerry C., Chaabane, Melanie M., Belal, Cherine, Nathanson, Jason L., Zoli, Michele, Leutgeb, Jill K., Biagini, Giuseppe, Yeo, Gene W., Berg, Darwin K.

“…A critical feature of neural networks is that they balance excitation and inhibition to prevent pathological dysfunction. How this is achieved is largely…”
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Evidence for premature aging due to oxidative stress in iPSCs from Cockayne syndrome by Andrade, Luciana Nogueira de Sousa, Nathanson, Jason L, Yeo, Gene W, Menck, Carlos Frederico Martins, Muotri, Alysson Renato

“…Cockayne syndrome (CS) is a human premature aging disorder associated with neurological and developmental abnormalities, caused by mutations mainly in the CS…”
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High-Throughput and Cost-Effective Characterization of Induced Pluripotent Stem Cells by D'Antonio, Matteo, Woodruff, Grace, Nathanson, Jason L, D'Antonio-Chronowska, Agnieszka, Arias, Angelo, Matsui, Hiroko, Williams, Roy, Herrera, Cheryl, Reyna, Sol M, Yeo, Gene W, Goldstein, Lawrence S B, Panopoulos, Athanasia D, Frazer, Kelly A

“…Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) offers the possibility of studying the molecular mechanisms underlying human diseases in…”
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Differential LINE-1 regulation in pluripotent stem cells of humans and other great apes by Marchetto, Maria C. N., Narvaiza, Iñigo, Denli, Ahmet M., Benner, Christopher, Lazzarini, Thomas A., Nathanson, Jason L., Paquola, Apuã C. M., Desai, Keval N., Herai, Roberto H., Weitzman, Matthew D., Yeo, Gene W., Muotri, Alysson R., Gage, Fred H.

“…Identifying cellular and molecular differences between human and non-human primates (NHPs) is essential to the basic understanding of the evolution and…”
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Preferential labeling of inhibitory and excitatory cortical neurons by endogenous tropism of AAV and lentiviral vectors by Nathanson, Jason L, Yanagawa, Yuchio, Obata, Kunihiko, Callaway, Edward M

“…Despite increasingly widespread use of recombinant adeno-associated virus (AAV) and lentiviral (LV) vectors for transduction of neurons in a wide range of…”
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